Results 21 to 30 of about 27,105 (199)

The role of endothelial glycocalyx in sepsis

Bali Journal of Anesthesiology, 2019
The surface of endothelial cells is filled with various membrane-bound molecules that form the glycocalyx. The endothelial glycocalyx is a surface layer mainly consisted of glycosaminoglycans that include heparan sulfate, chondroitin sulfate, and ...
I Nyoman Budi Hartawan, Made Wiryana
doaj   +1 more source

The Beneficial Effect of HES on Vascular Permeability and Its Relationship With Endothelial Glycocalyx and Intercellular Junction After Hemorrhagic Shock

Frontiers in Pharmacology, 2020
BackgroundVascular leakage is a common complication of hemorrhagic shock. Endothelial glycocalyx plays a crucial role in the protection of vascular endothelial barrier function.
Hongliang Zhao, Yu Zhu, Jie Zhang, Yue Wu, Xinming Xiang, Zisen Zhang, Tao Li, Liangming Liu   +7 more
doaj   +1 more source

The endothelial glycocalyx prefers albumin for evoking shear stress-induced, nitric oxide-mediated coronary dilatation [PDF]

, 2007
Background: Shear stress induces coronary dilatation via production of nitric oxide ( NO). This should involve the endothelial glycocalyx ( EG). A greater effect was expected of albumin versus hydroxyethyl starch ( HES) perfusion, because albumin seals ...
Bernhard F. Becker, Chang YS, Desjardins C, Dirk Bruegger, Gonzalez-Castillo C, Huxley VH, Joern O. Paul, Kuchan MJ, Leipert B, Markus Rehm, Matthias Jacob, Michael Loetsch, Mochizuki S, Mulivor AW, Peter Conzen, Platts SH, Pohl U, Pries AR, Risau W, Rubanyi GM, Siegel G, Ulrich Welsch, van Haaren P, Vink H, Vink H, Vink H   +25 more
core   +1 more source

Targeting repair of the vascular endothelium and glycocalyx after traumatic injury with plasma and platelet resuscitation

Matrix Biology Plus, 2022
Severely injured patients with hemorrhagic shock can develop endothelial dysfunction, systemic inflammation, and coagulation disturbances collectively known as the endotheliopathy of trauma (EOT). Shedding of the endothelial glycocalyx occurs early after
Mark Barry, Shibani Pati
doaj   +1 more source

Multiscale modelling of fluid and solute transport in soft tissues and microvessels [PDF]

, 2010
This study focuses on the movement of particles and extracellular fluid in soft tissues and microvessels. It analyzes modeling applications in biological and physiological fluids at a range of different length scales: from between a few tens to several ...
Lu, Yiling, Wang, Wen
core   +2 more sources

Pro-atherosclerotic disturbed flow disrupts caveolin-1 expression, localization, and function via glycocalyx degradation

Journal of Translational Medicine, 2018
Background Endothelial-dependent atherosclerosis develops in a non-random pattern in regions of vessel bending and bifurcations, where blood flow exhibits disturbed flow (DF) patterns.
Ian C. Harding, Ronodeep Mitra, Solomon A. Mensah, Ira M. Herman, Eno E. Ebong   +4 more
doaj   +1 more source

Perspectives in Microvascular Fluid Handling: Does the Distribution of Coagulation Factors in Human Myocardium Comply with Plasma Extravasation in Venular Coronary Segments? [PDF]

, 2010
Background: Heterogeneity of vascular permeability has been suggested for the coronary system. Whereas arteriolar and capillary segments are tight, plasma proteins pass readily into the interstitial space at venular sites.
Becker, Bernhard F., Bruegger, Dirk, Chappell, Daniel, Conzen, Peter, Jacob, Matthias, Kaczmarek, Ingo, Rehm, Markus, Stoeckelhuber, Mechthild, Welsch, Ulrich   +8 more
core   +1 more source

Sialic acids regulate microvessel permeability, revealed by novel in vivo studies of endothelial glycocalyx structure and function [PDF]

, 2017
The endothelial glycocalyx forms a continuous coat over the luminal surface of all vessels, and regulates multiple vascular functions. The contribution of individual components of the endothelial glycocalyx to one critical vascular function ...
Aamelfot, Adamson, Adamson, Adamson, Adamson, Adembri, Arkill, Bai, Baldwin, Barker, Bates, Bates, Bingaman, Born, Cai, Cassidy, Chappell, Cioffi, Cuniberti, Curry, Curry, Curry, Curry, Curry, Curry, Curry, Damiano, Dekan, Florian, Fu, Fu, Gao, Gelberg, Geyer, Gorog, Gretz, Haraldsson, Haraldsson, Hu, Huxley, Huxley, Jeansson, Jeansson, Jeansson, Kendall, Kumagai, Lee, Levick, Mason, Michel, Michel, Michel, Nassimizadeh, Oltean, Pahakis, Peti-Peterdi, Pries, Sakarya, Salmon, Salmon, Salmon, Schindelin, Singh, Squire, Tarbell, Tarbell, Tarbell, Tatsuzuki, Vargas, Varki, Weinbaum, Weinbaum, Yen, Zeng   +73 more
core   +3 more sources

Proteomics for prediction of disease progression and response to therapy in diabetic kidney disease [PDF]

, 2016
The past decade has resulted in multiple new findings of potential proteomic biomarkers of diabetic kidney disease (DKD). Many of these biomarkers reflect an important role in the (patho)physiology and biological processes of DKD.
Heerspink, Hiddo J.L., Mischak, Harald, Pena, Michelle J.   +2 more
core   +7 more sources

Fibroblast growth factor 10 attenuates chronic obstructive pulmonary disease by protecting against glycocalyx impairment and endothelial apoptosis

Respiratory Research, 2022
Highlights It is the first time to prove the confirm the endothelial glycocalyx impairment in COPD. FGF10 attenuates the development of emphysema and the shedding of glycocalyx induced by CSE in vivo.
Tian Jiang, Weiping Hu, Shaoyuan Zhang, Changhao Ren, Siyun Lin, Zhenyu Zhou, Hao Wu, Jun Yin, Lijie Tan   +8 more
doaj   +1 more source