Results 61 to 70 of about 571,172 (234)

Endothelial Damage and the Microcirculation in Critical Illness

open access: yesBiomedicines, 2022
Endothelial integrity maintains microcirculatory flow and tissue oxygen delivery. The endothelial glycocalyx is involved in cell signalling, coagulation and inflammation.
Rachael Cusack   +3 more
doaj   +1 more source

Surface wave excitations and backflow effect over dense polymer brushes [PDF]

open access: yes, 2016
Polymer brushes are being increasingly used to tailor surface physicochemistry for diverse applications such as wetting, adhesion of biological objects, implantable devices and much more.
BIAGI, SOFIA   +3 more
core   +1 more source

Protectin conjugates in tissue regeneration 1 restores lipopolysaccharide-induced pulmonary endothelial glycocalyx loss via ALX/SIRT1/NF-kappa B axis

open access: yesRespiratory Research, 2021
Background Endothelial glycocalyx loss is integral to increased pulmonary vascular permeability in sepsis-related acute lung injury. Protectin conjugates in tissue regeneration 1 (PCTR1) is a novel macrophage-derived lipid mediator exhibiting potential ...
Xin-Yang Wang   +9 more
doaj   +1 more source

Protective Treatments against Endothelial Glycocalyx Degradation in Surgery: A Systematic Review and Meta-Analysis

open access: yesApplied Sciences, 2021
The aim was to explore the body of literature focusing on protective treatments against endothelial glycocalyx degradation in surgery. A comprehensive systematic review of relevant articles was conducted across databases.
Hasnain Q. R. B. Khan   +1 more
doaj   +1 more source

Alterations in heparan sulfate proteoglycan synthesis and sulfation and the impact on vascular endothelial function

open access: yesMatrix Biology Plus, 2022
The glycocalyx attached to the apical surface of vascular endothelial cells is a rich network of proteoglycans, glycosaminoglycans, and glycoproteins with instrumental roles in vascular homeostasis.
Danielle Pretorius   +4 more
doaj   +1 more source

Assessment of pulmonary edema: principles and practice [PDF]

open access: yes, 2018
Pulmonary edema increasingly is recognized as a perioperative complication affecting outcome. Several risk factors have been identified, including those of cardiogenic origin, such as heart failure or excessive fluid administration, and those related to ...
Assaad, Sherif   +4 more
core   +1 more source

Association of COVID‐19 with impaired endothelial glycocalyx, vascular function and myocardial deformation 4 months after infection

open access: yesEuropean Journal of Heart Failure, 2021
SARS‐CoV‐2 infection may lead to endothelial and vascular dysfunction. We investigated alterations of arterial stiffness, endothelial coronary and myocardial function markers 4 months after COVID‐19 infection.
V. Lambadiari   +17 more
semanticscholar   +1 more source

The Role of Plasma Transfusion in Massive Bleeding: Protecting the Endothelial Glycocalyx?

open access: yesFrontiers in Medicine, 2018
Massive hemorrhage is a leading cause of death worldwide. During the last decade several retrospective and some prospective clinical studies have suggested a beneficial effect of early plasma-based resuscitation on survival in trauma patients.
Stefano Barelli   +2 more
doaj   +1 more source

The glycocalyx as a permeability barrier: basic science and clinical evidence

open access: yesCritical Care, 2022
Preclinical studies in animals and human clinical trials question whether the endothelial glycocalyx layer is a clinically important permeability barrier. Glycocalyx breakdown products in plasma mostly originate from 99.6–99.8% of the endothelial surface
Randal O. Dull, Robert G. Hahn
doaj   +1 more source

Inflammatory stimuli induce shedding of heparan sulfate from arterial but not venous porcine endothelial cells leading to differential proinflammatory and procoagulant responses

open access: yesScientific Reports, 2023
Endothelial dysfunction is an early event of vascular injury defined by a proinflammatory and procoagulant endothelial cell (EC) phenotype. Although endothelial glycocalyx disruption is associated with vascular damage, how various inflammatory stimuli ...
Anastasia Milusev   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy