Results 11 to 20 of about 1,271,424 (340)

Caspases and p38 MAPK regulate endothelial cell adhesiveness for mesenchymal stem cells. [PDF]

open access: yesPLoS ONE, 2013
Mesenchymal stem cells natively circulating or delivered into the blood stream home to sites of injury. The mechanism of mesenchymal stem cell homing to sites of injury is poorly understood.
Irina A Potapova   +2 more
doaj   +1 more source

Mesenchymal Stem Cells & Endothelial Function [PDF]

open access: yesEBioMedicine, 2015
In this issue of EBioMedicine, Premer et al. report their study titled “Allogeneic Mesenchymal Stem Cells Restore Endothelial Function in Heart Failure by Stimulating Endothelial Progenitor Cells” (Premer et al., 2015). They recruited a cohort of heart failure patients from two ongoing clinical trials evaluating both autologous and allogeneic ...
Roger J. Hajjar, Kenneth Fish
openaire   +4 more sources

Endothelial origin of mesenchymal stem cells [PDF]

open access: yesCell Cycle, 2011
Mesenchymal stem/stromal cells (MSCs) are fibroblastoid cells capable of long-term expansion and skeletogenic differentiation. While MSCs are known to originate from neural crest and mesoderm, immediate mesodermal precursors that give rise to MSCs have not been characterized.
Maxim A. Vodyanik, Igor I. Slukvin
openaire   +3 more sources

Endothelial Differentiation of Embryonic Stem Cells [PDF]

open access: yesCurrent Protocols in Stem Cell Biology, 2008
AbstractVascular progenitor cells derived from stem cells could potentially lead to a variety of clinically relevant applications, including cell‐based therapies and tissue engineering. Here, we describe methods for isolating purified proliferating populations of vascular endothelial cells from mouse embryonic stem cells (mESC) using Flk‐1 positive ...
Kara E. McCloskey   +2 more
openaire   +3 more sources

Discovering the Potential of Dental Pulp Stem Cells for Corneal Endothelial Cell Production: A Proof of Concept

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Failure of corneal endothelium cell monolayer is the main cause leading to corneal transplantation. Autologous cell-based therapies are required to reconstruct in vitro the cell monolayer.
Begoña M. Bosch   +5 more
doaj   +1 more source

Wnt-mediated endothelial transformation into mesenchymal stem cell–like cells induces chemoresistance in glioblastoma

open access: yesScience Translational Medicine, 2020
Glioblastoma-associated endothelial cells transform into mesenchymal stem cell–like cells via Wnt/β-catenin, inducing tumor resistance to chemotherapy.
Menggui Huang   +15 more
semanticscholar   +1 more source

A Novel Molecular and Functional Stemness Signature Assessing Human Cord Blood-Derived Endothelial Progenitor Cell Immaturity. [PDF]

open access: yesPLoS ONE, 2016
Endothelial Colony Forming Cells (ECFCs), a distinct population of Endothelial Progenitor Cells (EPCs) progeny, display phenotypic and functional characteristics of endothelial cells while retaining features of stem/progenitor cells.
Oriane Guillevic   +5 more
doaj   +1 more source

Co-growth of Stem Cells With Target Tissue Culture as an Easy and Effective Method of Directed Differentiation

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
The long-term co-culture of mouse embryonic stem cells (mESC) with rat endothelial cells (EC) was tested for contact differentiation into the endothelial lineage.
Marina Valentinovna Kovina   +7 more
doaj   +1 more source

Gap Junction–Mediated Transport of Metabolites Between Stem Cells and Vascular Endothelial Cells

open access: yesCell Transplantation, 2022
We have previously demonstrated that small molecular transfer, such as glucose, between hematopoietic stem cells (HSCs) or mesenchymal stem cells (MSCs) and vascular endothelial cells via gap junctions constitutes an important mechanism of stem cell ...
Yuko Ogawa   +8 more
doaj   +1 more source

Placental growth factor expression is required for bone marrow endothelial cell support of primitive murine hematopoietic cells. [PDF]

open access: yesPLoS ONE, 2013
Two distinct microenvironmental niches that regulate hematopoietic stem/progenitor cell physiology in the adult bone marrow have been proposed; the endosteal and the vascular niche.
Xiaoying Zhou   +2 more
doaj   +1 more source

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