Results 151 to 160 of about 208,585 (381)

Three apparent receptor subtypes for the endothelin/sarafotoxin family [PDF]

open access: bronze, 1989
Yoel Kloog   +3 more
openalex   +1 more source

Diffuse Melanosis Cutis Under Immuno‐ and Targeted Therapy

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT In patients with highly advanced melanoma, rarely a diffuse melanosis cutis (DMC) can be noticed. Even though the condition is generally harmless itself, it can have a significant impact on the patient's well‐being as an obvious mark of the disease. DMC causes a grey or brown discoloration of the skin and mucous membranes. We report on a young
Christiane Cussigh   +3 more
wiley   +1 more source

Kinetics of endothelin-1 and effect selective ETA antagonism on ETB activation: a mathematical modeling analysis

open access: yesFrontiers in Pharmacology
IntroductionEndothelin-1 (ET-1) regulates renal and vascular function, but the clinical utility of selective ETA receptor antagonists has been limited due to associated fluid retention.
K. Melissa Hallow   +5 more
doaj   +1 more source

Spontaneous Enlargement in Balloon Pulmonary Angioplasty With Undersized Balloon for Chronic Thromboembolic Pulmonary Hypertension

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Background Balloon pulmonary angioplasty (BPA) has emerged as an effective treatment for chronic thromboembolic pulmonary hypertension (CTEPH). Recent studies have reported progressive improvements in hemodynamic and clinical parameters during follow‐up, even without additional interventions.
Wenjie Dong   +8 more
wiley   +1 more source

Angiogenesis as a Therapeutic Target of (Poly)phenols: Tackling Cancer and Vascular‐Related Complications

open access: yesMolecular Nutrition &Food Research, EarlyView.
(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez   +5 more
wiley   +1 more source

Novel Treatment Paradigms: Primary IgA Nephropathy

open access: yesKidney International Reports
IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. Approximately 30% to 45% of patients progress to kidney failure (KF) within 20 to 25 years of diagnosis, and there has long been a lack of effective treatments.
Haresh Selvaskandan   +2 more
doaj  

History of pre‐eclampsia negatively impacts stroke severity postpartum in rats

open access: yesNeuroprotection, EarlyView.
Diagrammatic representation of the effect of pre‐eclampsia on postpartum stroke severity. e7, gestational day 7; ePE, experimental pre‐eclampsia; NormP, normal pregnancy; PP, postpartum; tMCAO, transient middle cerebral artery occlusion. Made in Biorender.
Ari Kropf   +4 more
wiley   +1 more source

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