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Endothelins and liver cirrhosis
Endothelins are a family of 21‐amino acid oligopeptides, called endothelin‐1 (ET‐1), endothelin‐2 (ET‐2), and endothelin 3 (ET‐3). Endothelins act on hepatocytes, liver endothelial cells, and Kupffer cells in a paracrine or autocrine manner through two G
Necati Örmeci
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Anti-Graying Effects of External and Internal Treatments with Luteolin on Hair in Model Mice [PDF]
Little is known about the anti-graying effects of antioxidants on hair. The anti-graying effects of three antioxidants (luteolin, hesperetin, and diosmetin) on hair were investigated according to the sequential processes of hair graying that were ...
Machiko Iida +7 more
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Vasoplegia is a condition characterized by persistent low systemic vascular resistance despite a normal or high cardiac index, resulting in profound and uncontrolled vasodilation. Vasoplegia may occur due to various conditions, including cardiac failure,
Iqbal Ratnani +3 more
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Role of Vasoactive Hormone-Induced Signal Transduction in Cardiac Hypertrophy and Heart Failure [PDF]
Heart failure is the common concluding pathway for a majority of cardiovascular diseases and is associated with cardiac dysfunction. Since heart failure is invariably preceded by adaptive or maladaptive cardiac hypertrophy, several biochemical mechanisms
Naranjan S. Dhalla +5 more
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Endothelin Signaling Mediates Biliary-Endothelial Crosstalk in Primary Sclerosing Cholangitis. [PDF]
Yin C.
europepmc +3 more sources
Glaucoma is a chronic and progressive eye disease, commonly associated with elevated intraocular pressure (IOP) and characterized by optic nerve degeneration, cupping of the optic disc, and loss of retinal ganglion cells (RGCs).
Bindu Kodati +18 more
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The present study deals with the molecular modeling studies of the endothelins (ETs), a multi-functional 21 amino acid (AA) peptides, with sub-types ET-I, II, and III to find the structure property relationship (SPR) of different fragments naturally ...
Khan Riaz A., Khan Azra J.
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Endothelins as mediators in the modulation of cardiac performance [PDF]
The role of endothelin in cardiovascular physiology and pathophysiology has been undeniable ever since its discovery. Endothelins in the heart are important for the development, growth and remodeling, as well as for the control of contractility and ...
Smiljić Sonja +4 more
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The Role of Endothelins, IL-18, and NGAL in Kidney Hypothermic Machine Perfusion
Ischemia-reperfusion injury (IRI) occurring after renal transplantation is a complex biochemical process that can be monitored by specific biomarkers. The roles of those are not yet fully elucidated.
Karol Tejchman +7 more
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Endothelins and Sarafotoxins: Peptides of Similar Structure and Different Function
Endothelins are endogenous vasoactive peptides that are considered among the most potent vasoconstrictor substances known. In addition to their vascular effects, endothelins and their receptors have been shown to be present in many organs and share ...
Jiří Patočka +3 more
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