Results 61 to 70 of about 3,316 (159)

Endotheliopathy is associated with slower liberation from mechanical ventilation: a cohort study

Critical Care, 2022
Background Endotheliopathy is suggested as pivotal pathophysiology of sepsis and trauma-associated organ failure, but its role in acute respiratory failure is not yet determined.
Martin Schønemann-Lund, Theis S. Itenov, Johan E. Larsson, Birgitte Lindegaard, Pär I. Johansson, Morten H. Bestle   +5 more
doaj   +1 more source

Where Do We Stand for Nerve Regeneration and Functional Recovery After Vascularized Composite Allotransplantation?

Microsurgery, Volume 46, Issue 2, February 2026.
ABSTRACT Introduction Vascularized composite allotransplantation (VCA) offers a reconstructive solution for patients with severe limb and facial defects by transplanting multiple tissue types—including skin, muscle, bone, and nerves—as a single unit.
Olivier Mathieu, Leonard Knoedler, Thomas Schaschinger, Jakob Fenske, Felix J. Klimitz, Maxime Jeljeli, Curtis L. Cetrulo Jr., Alexandre G. Lellouch   +7 more
wiley   +1 more source

Experimental Models of Endotheliopathy: Impact of Shock Severity

Shock, 2018
ABSTRACT Background: Hemorrhagic shock (HS) followed by resuscitation is often associated with sympathoadrenal activation (SAA) and endothelial damage (ED). Objective: We aimed to evaluate the impact of HS alone on the magnitude of SAA and consecutive ED, and to ...
Nikolaus, Hofmann, Johannes, Zipperle, Mohammad, Jafarmadar, Mostafa, Ashmwe, Claudia, Keibl, Carina, Penzenstadler, Martin, Ponschab, Behnaz, Jafarmadar, Heinz, Redl, Soheyl, Bahrami, Herbert, Schöchl   +10 more
openaire   +3 more sources

Remote Pancreatic Response to Severe Polytrauma Correlates With Clinical Outcome

United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background Acute pancreatic injury can result from blunt or sharp force trauma, often leading to serious complications. While direct pancreatic trauma is associated with high rates of infection, organ failure, and mortality, little is known about the pancreas as a potential secondary target and remote trauma organ and thereby as a booster of ...
Rebecca Halbgebauer, Lisa Wohlgemuth, Jonas Wrba, Sonja Braumüller, Enes Kumral, Ludmila Lupu, Clara Morgenstern, Lucas Bettac, Sebastian Wiese, Benjamin Mayer, Paolo Cinelli, Daniel Rittirsch, Hans‐Christoph Pape, Francesco Roselli, Thomas Seufferlein, Alexander Kleger, Markus Breunig, Markus Huber‐Lang   +17 more
wiley   +1 more source

Disseminated intravascular coagulation: new identity as endotheliopathy-associated vascular microthrombotic disease based on in vivo hemostasis and endothelial molecular pathogenesis

Thrombosis Journal, 2020
Disseminated intravascular coagulation (DIC) can be correctly redefined as disseminated intravascular microthrombosis based on “two-path unifying theory” of in vivo hemostasis.
Jae C. Chang
doaj   +1 more source

A 14‐Year‐Old Male With Susac Syndrome: A Case Report

Case Reports in Neurological Medicine, Volume 2026, Issue 1, 2026.
Introduction and Importance Susac syndrome (SuS) is a rare autoimmune microangiopathy involving the brain, retina, and inner ear. It is uncommon in children, and early diagnosis is essential to prevent irreversible deficits. Case Presentation A 14‐year‐old boy presented with decreased consciousness following 18 days of excessive sleepiness, vomiting ...
M-Jaber Kojak, Mouhammed Sleiay, Bilal Sleiay, Abdulrahman Dokhan, Ghassan Hamzeh, Hasan Alsmoudi, Bara’a Merie Alghadi, Suraiya Saleem   +7 more
wiley   +1 more source

Detecting Endothelial Compromise Objectively through Dynamic EASIX scoring (DECODE) - predictive utility of EASIX and modified EASIX scores for endothelial complications post hematopoietic cell transplant

Frontiers in Oncology
IntroductionEndothelial injury is a major contributor to morbidity and mortality in pediatric patients undergoing hematopoietic cell transplantation (HCT).
Saad Ghafoor, Saad Ghafoor, Kimberly Uchida, Kimberly Uchida, Kimberly Uchida, Jennifer McArthur, Jennifer McArthur, Yvonne Avent, Chia-Wei Hsu, Haitao Pan, Lama Elbahlawan   +10 more
doaj   +1 more source

Characterization of sympathicotonia in post‐covid condition (long covid) and healthy controls using long‐term electrodermal activity (EDA) follow‐up

Clinical Physiology and Functional Imaging, Volume 45, Issue 6, November 2025.
Abstract Purpose After SARS‐CoV‐2 infection, some patients develop post‐COVID condition (PCC), often associated with sympathicotonia. This study aimed to characterize sympathicotonia in PCC patients using a novel long‐term electrodermal activity (EDA) analysis via a smart ring and evaluate its clinical applicability. Methods Seventeen PCC patients were
Timo Mustonen, Pasi Kytölä, Hanna Lantto, Erika Lager, Velina Vangelova‐Korpinen, Hélène Virrantaus, Aleksandra Sulg, Sanna Stålnacke, Tatiana Posharina, Ritva Luukkonen, Arja Uusitalo, Päivi Piirilä, Mari Kanerva   +12 more
wiley   +1 more source

Revisiting the monocrotaline‐treated rat as a model of inflammatory lung disease: COVID‐19 and future pandemic threats?

Animal Models and Experimental Medicine, Volume 8, Issue 10, Page 1785-1793, October 2025.
In this review, the pathological, molecular, and cellular changes observed in the COVID‐19 lung are compared to those in the laboratory rat treated with monocrotaline (MCT). Similarities that reflect common changes associated with inflammation and endothelial cell dysfunction are observed in both states, leading to a lung pathology characterized by ...
Luke P. Kris, Dani‐Louise Dixon, Shailesh Bihari, Jillian M. Carr   +3 more
wiley   +1 more source

Systematic analysis of molecules regulating nitric oxide (NO) metabolism and vascular endothelium condition

Фармакоэкономика
Background. Nitric monooxide (NO) is a signaling molecule that plays an important role in many physiological processes, including the regulation of vascular tone, neurotransmission, immunity, mitochondrial respiration, and skeletal muscle contractility ...
I. Yu. Torshin, A. G. Chuchalin, O. A. Gromova   +2 more
doaj   +1 more source