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The Intestinal Lymphatic System: Functions and Metabolic ImplicationsSummary [PDF]

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2019
The lymphatic system of the gut plays important roles in the transport of dietary lipids, as well as in immunosurveillance and removal of interstitial fluid.
Vincenza Cifarelli, Anne Eichmann
doaj   +3 more sources

T Cell Migration from Inflamed Skin to Draining Lymph Nodes Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1 Interactions [PDF]

open access: yesCell Reports, 2017
T cells are the most abundant cell type found in afferent lymph, but their migration through lymphatic vessels (LVs) remains poorly understood. Performing intravital microscopy in the murine skin, we imaged T cell migration through afferent LVs in vivo ...
Alvaro Teijeira   +10 more
doaj   +5 more sources

Transcription Factor Control of Lymphatic Quiescence and Maturation of Lymphatic Neovessels in Development and Physiology

open access: yesFrontiers in Physiology, 2021
The lymphatic system is a vascular system comprising modified lymphatic endothelial cells, lymph nodes and other lymphoid organs. The system has diverse, but critical functions in both physiology and pathology, and forms an interface between the blood ...
Zarah B. Tabrizi   +4 more
doaj   +1 more source

Lymphatic Clearance of Immune Cells in Cardiovascular Disease

open access: yesCells, 2021
Recent advances in our understanding of the lymphatic system, its function, development, and role in pathophysiology have changed our views on its importance. Historically thought to be solely involved in the transport of tissue fluid, lipids, and immune
Christophe Ravaud   +4 more
doaj   +1 more source

Visualization of Endothelial Actin Cytoskeleton in the Mouse Retina [PDF]

open access: yes, 2012
Angiogenesis requires coordinated changes in cell shape of endothelial cells (ECs), orchestrated by the actin cytoskeleton. The mechanisms that regulate this rearrangement in vivo are poorly understood - largely because of the difficulty to visualize ...
Alessia Fraccaroli   +10 more
core   +11 more sources

KSHV infection of endothelial precursor cells with lymphatic characteristics as a novel model for translational Kaposi's sarcoma studies.

open access: yesPLoS Pathogens, 2023
Kaposi's sarcoma herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma (KS), a hyperplasia consisting of enlarged malformed vasculature and spindle-shaped cells, the main proliferative component of KS.
Krista Tuohinto   +7 more
doaj   +1 more source

Is It All about Endothelial Dysfunction? Focusing on the Alteration in Endothelial Integrity as a Key Determinant of Different Pathological Mechanisms

open access: yesBiomedicines, 2022
The endothelium is composed of a monolayer of endothelial cells (ECs) covering the inner side of arterial, venous and lymphatic vessels [...]
Pasquale Ambrosino   +3 more
doaj   +1 more source

Coagulation in Lymphatic System

open access: yesFrontiers in Cardiovascular Medicine, 2021
The lymphatic system maintains homeostasis of the internal environment between the cells in tissues and the blood circulation. The coagulation state of lymph is determined by conditions of coagulation factors and lymphatic vessels. Internal obliteration,
Wendi Zhang   +8 more
doaj   +1 more source

Endothelial Dysfunction: From a Pathophysiological Mechanism to a Potential Therapeutic Target

open access: yesBiomedicines, 2021
The endothelium is considered the largest organ of the body, composed of a monolayer of endothelial cells (ECs) lining the interior surface of blood and lymphatic vessels [...]
Pasquale Ambrosino   +2 more
doaj   +1 more source

Plasticity of blood- and lymphatic endothelial cells and marker identification. [PDF]

open access: yesPLoS ONE, 2013
The distinction between lymphatic and blood vessels is biologically fundamental. Here we wanted to rigorously analyze the universal applicability of vascular markers and characteristics of the two widely used vascular model systems human microvascular ...
Johannes Keuschnigg   +8 more
doaj   +1 more source

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