Results 11 to 20 of about 44,150 (281)
Hematopoietic stem cells contribute to lymphatic endothelium.
BackgroundAlthough the lymphatic system arises as an extension of venous vessels in the embryo, little is known about the role of circulating progenitors in the maintenance or development of lymphatic endothelium.
Shuguang Jiang +6 more
doaj +3 more sources
Lymphatic endothelium in health and disease [PDF]
The lymphatic vascular system has an important role in the maintenance of tissue fluid pressure homeostasis, in the mediation of the afferent immune response via recruitment of antigen-presenting cells toward draining lymph nodes, and in the intestinal ...
Detmar, Michael, Jurisic, Giorgia
core +5 more sources
Immunomodulatory properties of the lymphatic endothelium in the tumor microenvironment
The tumor microenvironment (TME) is an intricate complex and dynamic structure composed of various cell types, including tumor, stromal and immune cells.
Cristina Viúdez-Pareja +5 more
doaj +3 more sources
Pannexin1 deletion in lymphatic endothelium affects lymphatic function in a sex‐dependent manner
The lymphatic network of capillaries and collecting vessels ensures tissue fluid homeostasis, absorption of dietary fats and trafficking of immune cells.
Avigail Ehrlich +5 more
doaj +4 more sources
Connexin-45 is expressed in mouse lymphatic endothelium and required for lymphatic valve function
The expression and functional relevance of the gap junction molecule connexin-45 (Cx45; GJC1) in lymphatic endothelium were not previously known. We found that Cx45 was expressed widely in the endothelium of murine lymphatics, in both valve and nonvalve ...
Michael J. Davis +6 more
doaj +3 more sources
The lymphatic microvasculature is uniquely adapted for the continuous removal of interstitial fluid and proteins, and is an important point of entry for leukocytes and tumor cells. The traditional view that lymphatic capillaries are passive participants in these tasks is currently being challenged.
Michael S. Pepper, Mihaela Skobe
openaire +3 more sources
Dendritic Cell Interactions with Lymphatic Endothelium [PDF]
Afferent lymphatic vessels fulfill essential immune functions by transporting leukocytes and lymph-borne antigen to draining lymph nodes (dLNs). An important cell type migrating through lymphatic vessels are dendritic cells (DCs). DCs reside in peripheral tissues like the skin, where they take up antigen and transport it via the lymphatic vascular ...
Russo Erica +2 more
openaire +3 more sources
The inflammatory response of lymphatic endothelium [PDF]
ISSN:1573 ...
Aebischer David +2 more
openaire +5 more sources
Culturing Purifies Murine Lymph Node Lymphatic Endothelium [PDF]
Lymph node (LN) lymphatic sinuses transport lymph, cells, and antigens from the periphery through the LN. The lymphatic endothelium lining these sinuses appears to be an important contributor to the lymph node immune response. It has been challenging to obtain sufficient LN lymphatic endothelial cells for investigation of their functions, as they are ...
Kimberly L, Jordan-Williams +1 more
openaire +2 more sources
Calcium and electrical dynamics in lymphatic endothelium [PDF]
Key points Endothelial cell function in resistance arteries integrates Ca2+ signalling with hyperpolarization to promote relaxation of smooth muscle cells and increase tissue blood flow. Whether complementary signalling occurs in lymphatic endothelium is unknown.
Erik J. Behringer +7 more
openaire +2 more sources

