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Engineered cardiac tissues [PDF]
Current Opinion in Biotechnology, 2011 Cardiac tissue engineering offers the promise of creating functional tissue replacements for use in the failing heart or for in vitro drug screening. The last decade has seen a great deal of progress in this field with new advances in interdisciplinary areas such as developmental biology, genetic engineering, biomaterials, polymer science, bioreactor ...
Rohin K, Iyer +3 more
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Cardiac Tissue Engineering [PDF]
Journal of Cardiovascular Nursing, 2009 The first 2 reviews in this series have described the defining properties of stem cells, their possible sources, and some initial attempts at their clinical use for tissue regeneration and repair. This third and final article in the series describes bioengineering methods for building physical structures to contain and organize implanted cells.
Matthew W, Curtis, Brenda, Russell
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Cardiac Tissue Engineering [PDF]
Circulation Research, 2014 The engineering of 3-dimensional (3D) heart muscles has undergone exciting progress for the past decade. Profound advances in human stem cell biology and technology, tissue engineering and material sciences, as well as prevascularization and in vitro assay technologies make the first clinical application of engineered cardiac tissues a realistic option
George Eng +3 more
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Engineering virtual cardiac tissue [PDF]
Briefings in Bioinformatics, 2001 The kinetics of proteins involved in ion transfer, sequestration and binding in cardiac cells can be modelled to construct a model of the electrical activity of isolated cardiac cells as a system of ordinary differential equations. These cell models may be incorporated into tissue models, which, when combined with histology and anatomy, form virtual ...
Boyett, M. R., Holden, A. V., Zhang, H.
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Engineered Human Cardiac Tissue [PDF]
Pediatric Cardiology, 2011 The human heart is the first organ to develop during embryogenesis and is arguably the most essential organ for life. However, after birth, the heart has very little capacity to repair malformations such as congenital heart defects or to regenerate after an injury such as myocardial infarction.
Kareen L, Kreutziger, Charles E, Murry
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Transplant Immunology, 2002 Recent progress in implantations of differentiated cardiac and non-cardiac cells as well as adult stem cells into the heart suggests that the irreversible loss of viable cardiac myocytes that occurs during myocardial infarction can be at least partly substituted.
Eschenhagen, Thomas +4 more
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Functional Cardiac Tissue Engineering [PDF]
Regenerative Medicine, 2012 Heart attack remains the leading cause of death in both men and women worldwide. Stem cell-based therapies, including the use of engineered cardiac tissues, have the potential to treat the massive cell loss and pathological remodeling resulting from heart attack.
Brian, Liau +2 more
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Stem Cells International, 2020 Cardiac tissue engineering using hiPSC-derived cardiomyocytes is a promising avenue for cardiovascular regeneration, pharmaceutical drug development, cardiotoxicity evaluation, and disease modeling.
Cassady E. Rupert +3 more
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Engineering and Assessing Cardiac Tissue Complexity [PDF]
International Journal of Molecular Sciences, 2021 Cardiac tissue engineering is very much in a current focus of regenerative medicine research as it represents a promising strategy for cardiac disease modelling, cardiotoxicity testing and cardiovascular repair. Advances in this field over the last two decades have enabled the generation of human engineered cardiac tissue constructs with progressively ...
Karine Tadevosyan +4 more
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Some International Constitutional Aspects of the Palestine Case [PDF]
, 1968 Cardiac tissue engineering via the use of stem cells is the future for repairing impaired heart function that results from a myocardial infarction.
Gelmi, Amy +3 more
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