Results 61 to 70 of about 1,265,582 (308)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Dual Melatonin Enhances Coordination Between Carbon and Nitrogen Assimilation in Soybean

Agriculture
Soybean production is currently insufficient to meet global demand, highlighting the need for strategies to enhance growth. Melatonin (MT) has emerged as a promising solution due to its growth-promoting properties.
Yanhong Wang, Xijun Jin, Yuxian Zhang
doaj   +1 more source

Enhanced 2,4-D Metabolism in Two Resistant Papaver rhoeas Populations from Spain

Frontiers in Plant Science, 2017
Corn poppy (Papaver rhoeas), the most problematic broadleaf weed in winter cereals in Southern Europe, has developed resistance to the widely-used herbicide, 2,4-D.
Joel Torra, Antonia M. Rojano-Delgado, Jordi Rey-Caballero, Aritz Royo-Esnal, Maria L. Salas, Rafael De Prado   +5 more
doaj   +1 more source

Major ginsenosides from Panax ginseng promote aerobic cellular respiration and SIRT1-mediated mitochondrial biosynthesis in cardiomyocytes and neurons

Journal of Ginseng Research, 2022
Background: Aerobic cellular respiration provides chemical energy, adenosine triphosphate (ATP), to maintain multiple cellular functions. Sirtuin 1 (SIRT1) can deacetylate peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α) to ...
Qingxia Huang, Tingting Lou, Jing Lu, Manying Wang, Xuenan Chen, Linyuan Xue, Xiaolei Tang, Wenxiu Qi, Zepeng Zhang, Hang Su, Wenqi Jin, Chenxu Jing, Daqing Zhao, Liwei Sun, Xiangyan Li   +14 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Cb1 Enhanced Osteogenic Differentiation Of Bmscs By Rescue Mitochondrial Metabolism

International Dental Journal
Aim or purpose: CB1 is the main effector of endogenous cannabinoid system, and our previous study verified CB1 enhanced the osteo/dentinogenic differentiation of dental mesenchymal stem cells (MSCs), which might be a target for alveolar bone regeneration.
Wanhao Yan
doaj   +1 more source

Tilting Plant Metabolism for Improved Metabolite Biosynthesis and Enhanced Human Benefit

Molecules, 2015
The immense chemical diversity of plant-derived secondary metabolites coupled with their vast array of biological functions has seen this group of compounds attract considerable research interest across a range of research disciplines.
Bhekumthetho Ncube, Johannes Van Staden
doaj   +1 more source

Physiological and Proteomic Responses of Pitaya to PEG-Induced Drought Stress

Agriculture, 2021
Pitaya (Hylocereus polyrhizus L.) is highly tolerant to drought stress. Elucidating the response mechanism of pitaya to drought will substantially contribute to improving crop drought tolerance.
Aihua Wang, Chao Ma, Hongye Ma, Zhilang Qiu, Xiaopeng Wen   +4 more
doaj   +1 more source

Targeting NAD+ Metabolism to Enhance Radiation Therapy Responses [PDF]

Seminars in Radiation Oncology, 2019
Nicotinamide adenine dinucleotide (NAD+) metabolism is integrally connected with the mechanisms of action of radiation therapy and is altered in many radiation-resistant tumors. This makes NAD+ metabolism an ideal target for therapies that increase radiation sensitivity and improve patient outcomes.
Lewis, Joshua E., Singh, Naveen, Holmila, Reetta J., Sumer, Baran D., Williams, Noelle S., Furdui, Cristina M., Kemp, Melissa L., Boothman, David A.   +7 more
openaire   +2 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source