Results 61 to 70 of about 1,268,330 (308)

Dual Melatonin Enhances Coordination Between Carbon and Nitrogen Assimilation in Soybean

Agriculture
Soybean production is currently insufficient to meet global demand, highlighting the need for strategies to enhance growth. Melatonin (MT) has emerged as a promising solution due to its growth-promoting properties.
Yanhong Wang, Xijun Jin, Yuxian Zhang
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Cb1 Enhanced Osteogenic Differentiation Of Bmscs By Rescue Mitochondrial Metabolism

International Dental Journal
Aim or purpose: CB1 is the main effector of endogenous cannabinoid system, and our previous study verified CB1 enhanced the osteo/dentinogenic differentiation of dental mesenchymal stem cells (MSCs), which might be a target for alveolar bone regeneration.
Wanhao Yan
doaj   +1 more source

Enhanced 2,4-D Metabolism in Two Resistant Papaver rhoeas Populations from Spain

Frontiers in Plant Science, 2017
Corn poppy (Papaver rhoeas), the most problematic broadleaf weed in winter cereals in Southern Europe, has developed resistance to the widely-used herbicide, 2,4-D.
Joel Torra, Antonia M. Rojano-Delgado, Jordi Rey-Caballero, Aritz Royo-Esnal, Maria L. Salas, Rafael De Prado   +5 more
doaj   +1 more source

Major ginsenosides from Panax ginseng promote aerobic cellular respiration and SIRT1-mediated mitochondrial biosynthesis in cardiomyocytes and neurons

Journal of Ginseng Research, 2022
Background: Aerobic cellular respiration provides chemical energy, adenosine triphosphate (ATP), to maintain multiple cellular functions. Sirtuin 1 (SIRT1) can deacetylate peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α) to ...
Qingxia Huang, Tingting Lou, Jing Lu, Manying Wang, Xuenan Chen, Linyuan Xue, Xiaolei Tang, Wenxiu Qi, Zepeng Zhang, Hang Su, Wenqi Jin, Chenxu Jing, Daqing Zhao, Liwei Sun, Xiangyan Li   +14 more
doaj   +1 more source

Local generation of hydrogen for enhanced photothermal therapy. [PDF]

, 2018
By delivering the concept of clean hydrogen energy and green catalysis to the biomedical field, engineering of hydrogen-generating nanomaterials for treatment of major diseases holds great promise.
Chen, Danyang, Chen, Qian, Gu, Zhen, He, Qianjun, Jin, Zhaokui, Lu, Xifeng, Meng, Jin, Yang, Tian, Zhao, Penghe   +8 more
core   +2 more sources

Targeting NAD+ Metabolism to Enhance Radiation Therapy Responses [PDF]

Seminars in Radiation Oncology, 2019
Nicotinamide adenine dinucleotide (NAD+) metabolism is integrally connected with the mechanisms of action of radiation therapy and is altered in many radiation-resistant tumors. This makes NAD+ metabolism an ideal target for therapies that increase radiation sensitivity and improve patient outcomes.
Lewis, Joshua E., Singh, Naveen, Holmila, Reetta J., Sumer, Baran D., Williams, Noelle S., Furdui, Cristina M., Kemp, Melissa L., Boothman, David A.   +7 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tilting Plant Metabolism for Improved Metabolite Biosynthesis and Enhanced Human Benefit

Molecules, 2015
The immense chemical diversity of plant-derived secondary metabolites coupled with their vast array of biological functions has seen this group of compounds attract considerable research interest across a range of research disciplines.
Bhekumthetho Ncube, Johannes Van Staden
doaj   +1 more source

Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer. [PDF]

, 2016
Renal cell carcinoma (RCC) is increasing in incidence, and a complete cure remains elusive. While immune-checkpoint antibodies are promising, interferon-based immunotherapy has been disappointing.
Abu Aboud, Omran, Anderson, Katie, Berryhill, Grace, Chen, Ching-Hsien, Graef, Ashley, Hovey, Russell C, Kim, Jeffrey, Modiano, Jaime F, Sarver, Aaron L, Stewart, Benjamin, Trott, Josephine F, Uzal, Francisco, Weiss, Robert H, Wettersten, Hiromi   +13 more
core   +2 more sources