Results 41 to 50 of about 308,220 (199)
Enhancement of Polio-RNA Infectivity by Dimethylsulfoxide
Experimental Biology and Medicine, 1966 SummaryDimethylsulfoxide (DMSO) has been shown to enhance infection by polio-RNA. This enhancement was present for all concentrations of DMSO from 5% to 80%. The enhancement was optimal at 40% DMSO with a 20-minute absorption period at room temperature.
M S, Amstey, P D, Parkman
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IntaRNA 2.0: enhanced and customizable prediction of RNA–RNA interactions [PDF]
Nucleic Acids Research, 2017 The IntaRNA algorithm enables fast and accurate prediction of RNA-RNA hybrids by incorporating seed constraints and interaction site accessibility. Here, we introduce IntaRNAv2, which enables enhanced parameterization as well as fully customizable control over the prediction modes and output formats.
Martin Mann +2 more
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Early-life undernutrition induces enhancer RNA remodeling in mice liver
Epigenetics & Chromatin, 2021 Background Maternal protein restriction diet (PRD) increases the risk of metabolic dysfunction in adulthood, the mechanisms during the early life of offspring are still poorly understood.
Yinyu Wang +9 more
doaj +1 more source
Research and Reports in Urology, 2021 Koichi Nishimura,1,2,* Jinichi Mori,1– 3,* Takahiro Sawada,1,2 Shuhei Nomura,1,4 Alexander Kouzmenko,1 Kaori Yamashita,5 Yoshiaki Kanemoto,1,2 Tomohiro Kurokawa,1,2 Akira Hayakawa,1 Suguru Tokiwa,5 Michihisa Ochi,5 Hiroaki Shimmura,5 Shigeaki ...
Nishimura K +12 more
doaj
Enhancer RNAs: mechanisms in transcriptional regulation and functions in diseases
Cell Communication and Signaling, 2023 In recent years, increasingly more non-coding RNAs have been detected with the development of high-throughput sequencing technology, including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), small nucleolar RNAs (snoRNAs ...
Qianhui Li +5 more
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Minor Loops in Major Folds: Enhancer-Promoter Looping, Chromatin Restructuring, and Their Association with Transcriptional Regulation and Disease. [PDF]
, 2015 The organization and folding of chromatin within the nucleus can determine the outcome of gene expression. Recent technological advancements have enabled us to study chromatin interactions in a genome-wide manner at high resolution.
Ahituv, Nadav, Matharu, Navneet
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A Perspective on the Enhancer Dependent Bacterial RNA Polymerase [PDF]
Biomolecules, 2015 Here we review recent findings and offer a perspective on how the major variant RNA polymerase of bacteria, which contains the sigma54 factor, functions for regulated gene expression. We consider what gaps exist in our understanding of its genetic, biochemical and biophysical functioning and how they might be addressed.
Zhang, N, Buck, M
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LSD1 Controls Timely MyoD Expression via MyoD Core Enhancer Transcription
Cell Reports, 2017 MyoD is a master regulator of myogenesis. Chromatin modifications required to trigger MyoD expression are still poorly described. Here, we demonstrate that the histone demethylase LSD1/KDM1a is recruited on the MyoD core enhancer upon muscle ...
Isabella Scionti +14 more
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MEF2C regulates outflow tract alignment and transcriptional control of Tdgf1 [PDF]
, 2016 Congenital heart defects are the most common birth defects in humans, and those that affect the proper alignment of the outflow tracts and septation of the ventricles are a highly significant cause of morbidity and mortality in infants.
Barnes, Ralston M. +9 more
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KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function [PDF]
, 2018 Estrogen receptor alpha (ER alpha) is a ligand-activated nuclear receptor that directs proliferation and differentiation in selected cancer cell types including mammary-derived carcinomas.
Abdel-Wahab, Omar +13 more
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