Kinetics of chymotrypsin- and papain-catalysed synthesis of [leucine]enkephalin and [methionine]enkephalin [PDF]
The proteinase-catalysed synthesis of [Leu]enkephalin and [Met]enkephalin was studied kinetically. N alpha-t-Butoxycarbonyl-amino acids and peptides or their ethyl esters served as acyl donors, and amino acid phenylhydrazides were used as acyl acceptors.
openaire +3 more sources
Dynamic Metabolic Footprinting Reveals the Key Components of Metabolic Network in Yeast Saccharomyces cerevisiae [PDF]
Metabolic footprinting offers a relatively easy approach to exploit the potentials of metabolomics for phenotypic characterization of microbial cells.
Chumnanpuen, Pramote+3 more
core +3 more sources
N‐ to C‐Peptide Synthesis, Arguably the Future for Sustainable Production
The advent of epimerization‐free methods for coupling in N‐ to C‐direction synthesis offers improved atom economy for sustainable peptide synthesis. ABSTRACT A revolution in peptide production arrived from the innovation of carboxylate to amine C‐ to N‐direction solid‐phase synthesis.
Kinshuk Ghosh, William D. Lubell
wiley +1 more source
Neuronal pathways in tendon healing and tendinopathy : update [PDF]
The regulatory mechanisms involved in tendon homeostasis and repair are not fully understood. Accumulating data, however, demonstrate that the nervous system, in addition to afferent (sensory) functions, through efferent neuronal pathways plays an active
Ackermann, Paul+5 more
core +1 more source
The study identified dysregulated fatty acid metabolism and inflammation as contributors to physio‐cognitive decline syndrome (PCDS). Sex‐specific metabolic disruptions were noted, with altered central carbon and tyrosine metabolism more pronounced in men and glutathione pathway perturbations more evident in women.
Yi‐Long Huang+7 more
wiley +1 more source
Application of Ion-Molecule Reactions to Structure Characterization and Thermochemical Property Measurements [PDF]
This thesis explores several novel applications of gas-phase ion-molecule reactions to solve analytical problems. In all cases, the application of an ion-molecule reaction to solve a specific challenge is based on a thorough understanding of the ...
Lin, Mingxiang
core
Catalytic Serine Labeling in Nonaqueous, Acidic Media
Serine‐targeting protein bioconjugation has been a formidable challenge because of the modest reactivity of the alkyl alcohol group in aqueous media. This work demonstrates a biomolecule‐compatible, nonaqueous approach to achieve alkyl alcohol‐selective labeling through acid‐catalyzed esterification reactions, which offers a unique advantage over the ...
Seiya Ishizawa+5 more
wiley +1 more source
Beef hydrolysis by Zyactinase™ enzymes : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy at Massey University, Auckland, New Zealand. [PDF]
Protein hydrolysis is the term that applies to all possible ways of splitting proteins to produce products with lower molecular weight. There is a continuous search for novel products derived from waste materials.
Ahmad, Noriza Binti
core
Rh‐Catalyzed Hydroamination of Allenes: Asymmetric N‐Allylation of Amino Acids and Peptides
A rhodium‐catalyzed, atom‐economic method for the branched‐selective hydroamination of terminal allenes with α‐amino acid esters is reported. High levels of enantio‐ and diastereoselectivity were achieved by using commercially available ligands, with complete catalyst control demonstrated in several products.
Edward Damer, Bernhard Breit
wiley +1 more source
Electron scattering from molecules and molecular aggregates of biological relevance [PDF]
In this Topical Review we survey the current state of the art in the study of low energy electron collisions with biologically relevant molecules and molecular clusters.
Allan M+33 more
core +1 more source