Results 101 to 110 of about 46,429 (222)

Anti‐Inflammatory and Antibacterial Properties of Curcuma longa Extract Against Helicobacter pylori

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 20, October 2025.
This study explored the effects of Curcuma longa extract (CLE) against H. pylori infection. CLE contained 18 chemical compounds and completely inhibited growth of H. pylori Sydney strain 1 (SS1) in vitro. In infected mice with H. pylori SS1, oral administration of CLE successfully eradicated H.
Jeongsook Kim   +7 more
wiley   +1 more source

Dendranthema oreastrum (Hance) Y.Ling Attenuates Oxidative Stress and Airway Inflammation in a Murine Model of Lipopolysaccharide‐Induced Acute Lung Injury

open access: yesEnvironmental Toxicology, Volume 40, Issue 10, Page 1220-1232, October 2025.
ABSTRACT We examined the antioxidant and anti‐inflammatory effects of the methanolic extract of Dendranthema oreastrum (Hance) Y.Ling, commonly known as “Gu‐Jeol‐Cho” in Korea and widely found across East Asia, using an LPS‐induced acute lung injury (ALI) mouse model and TNF‐α‐stimulated NCI‐H292 cells.
Ji‐Hye Ha   +11 more
wiley   +1 more source

Characterization and Identification of Potential Antioxidant, Antidiabetic, and Antihypertensive Peptides From Hydrolysates of Tenebrio molitor Flour and Its Protein Concentrate

open access: yesJournal of Food Science, Volume 90, Issue 10, October 2025.
ABSTRACT Insects are recognized as a potential alternative source of proteins and have been studied in recent years as a substrate for enzymatic hydrolysis to obtain bioactive peptides. This study aimed to evaluate the production of hydrolysates with antioxidant, antidiabetic, and antihypertensive properties from mealworm (Tenebrio molitor) flour and ...
Francielle Miranda de Matos   +1 more
wiley   +1 more source

Identification of MscS as a Key L‐Glutamate Exporter in Bacillus methanolicus

open access: yesMicrobial Biotechnology, Volume 18, Issue 10, October 2025.
l‐Glutamate export in the methylotrophic bacterium Bacillus methanolicus, driven by an MscS‐like mechanosensitive channel. Figure created with BioRender (https://BioRender.com/t99s28). ABSTRACT Small‐conductance mechanosensitive channels (MscS) are established l‐glutamate exporters in industrially relevant bacteria, yet their role in the methylotrophic
Luciana Fernandes Brito   +5 more
wiley   +1 more source

Differential Changes in Striatal Projection Neurons in R6/2 Transgenic Mice for Huntington's Disease

open access: yesNeurobiology of Disease, 2002
In early adult-onset Huntington's disease (HD), enkephalinergic striatopallidal projection neurons show preferential loss, reduced preproenkephalin (PPE) expression in surviving striatopallidal neurons, and loss of fibers in their projection target area.
Z. Sun   +4 more
doaj   +1 more source

Unfolding Hidden Barriers by Active Enhanced Sampling

open access: yes, 2017
Collective variable (CV) or order parameter based enhanced sampling algorithms have achieved great success due to their ability to efficiently explore the rough potential energy landscapes of complex systems.
Chen, Ming, Zhang, Jing
core   +1 more source

Bioprospecting Heavy‐Metal Rhizospheres for Novel Therapeutics Against High‐Priority Multi‐Drug‐Resistant Pseudomonas aeruginosa and Acinetobacter baumannii: A Case of Toxic to Treatment

open access: yesEnvironmental Microbiology Reports, Volume 17, Issue 5, October 2025.
Heavy metal stress induced the secretion of metabolites not secreted by non‐stressed microbiota. Heavy metal‐stressed microbiota secrete metabolites that inhibit XDR pathogens effectively. UPLC LC–MS tentatively identified novel metabolites, Tolyposamine and Gentiatibetine.
Kylah B. Millard   +4 more
wiley   +1 more source

Pain Perception and Modulation: Fundamental Neurobiology and Recent Advances

open access: yesEuropean Journal of Neuroscience, Volume 62, Issue 8, October 2025.
Chronic pain is a major burden with variable treatment responses reflecting complex biopsychosocial and neurobiological factors. This narrative review synthesizes evidence on neural structures, circuits, and mediators involved in pain perception and modulation.
Willem W. J. van Strien   +1 more
wiley   +1 more source

Double labelling immunohistochemical characterization of autonomic sympathetic neurons innervating the sow retractor clitoridis muscle [PDF]

open access: yes, 2008
Retrograde neuronal tracing and immunohistochemical methods were used to define the neurochemical content of sympathetic neurons projecting to the sow retractor clitoridis muscle (RCM). Differently from the other smooth muscles of genital organs, the RCM
Acone, Franca   +6 more
core  

The pharmacotherapeutic potential of neuropeptide Y for chronic pain

open access: yesJournal of Internal Medicine, Volume 298, Issue 4, Page 280-296, October 2025.
Abstract Chronic pain is a major medical problem that requires new therapeutic options. Discovered by Victor Mutt in 1982, neuropeptide Y (NPY) is rapidly emerging as a master regulator of pain relief. Genetic knockdown of NPY or pharmacological inhibition of its receptors demonstrates that NPY signaling tonically inhibits indices of chronic ...
Al A. Nie, Bradley K. Taylor
wiley   +1 more source

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