Results 111 to 120 of about 47,074 (275)

LC‐MS Analysis and Antimicrobial Activity of Different Extracts of Spondias purpurea L

open access: yesChemistrySelect, Volume 10, Issue 34, September 8, 2025.
The present research showed that the extracts tested alone do not present significant antibacterial or antifungal activities at low concentrations against the tested strains. However, they demonstrated potentiating effect of already standardized drugs. Abstract Spondias purpurea L.
Maria Elenilda Paulino da Silva   +15 more
wiley   +1 more source

Contributions of synaptic energetic dysfunction by microtubule dynamics and microtubule‐based mitochondrial transport disorder to morphine tolerance

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 17, Page 4058-4079, September 2025.
Abstract Background and Purpose Morphine is among the most powerful analgesic, but its long‐term use can cause tolerance. Synaptic ATP supply is critical for maintaining synaptic transmission. Microtubule‐based mitochondrial transport ensures synaptic energy supply.
Zheng Li   +9 more
wiley   +1 more source

Double labelling immunohistochemical characterization of autonomic sympathetic neurons innervating the sow retractor clitoridis muscle [PDF]

open access: yes, 2008
Retrograde neuronal tracing and immunohistochemical methods were used to define the neurochemical content of sympathetic neurons projecting to the sow retractor clitoridis muscle (RCM). Differently from the other smooth muscles of genital organs, the RCM
Acone, Franca   +6 more
core  

Multi-physics Extension of OpenFMO Framework

open access: yes, 2007
OpenFMO framework, an open-source software (OSS) platform for Fragment Molecular Orbital (FMO) method, is extended to multi-physics simulations (MPS). After reviewing the several FMO implementations on distributed computer environments, the subsequent ...
George Maroulis   +11 more
core   +1 more source

GPCR‐G protein signalling and its mutational landscape in cancer—Driver or passenger

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 17, Page 3975-3989, September 2025.
G protein‐coupled receptors (GPCRs) play a crucial role in cellular signalling, regulating various physiological processes. Abnormal expression and mutations of GPCRs have been implicated in several types of cancer, influencing tumour initiation, progression and immune response.
Chenlin Feng   +3 more
wiley   +1 more source

Isolation and amino acid sequence analysis of a 4,000-dalton dynorphin from porcine pituitary [PDF]

open access: yes, 1982
A 4,000-dalton dynorphin was isolated from porcine pituitary. It has 32 amino acids (Mr = 3,986), with the previously described heptadecapeptide (now called dynorphin A) at its amino terminus and a related tridecapeptide, dynorphin B, at its carboxyl ...
Fischli, Walter   +3 more
core  

Replica-exchange multicanonical algorithm and multicanonical replica-exchange method for simulating systems with rough energy landscape

open access: yes, 2000
We propose two efficient algorithms for configurational sampling of systems with rough energy landscape. The first one is a new method for the determination of the multicanonical weight factor.
Bartels   +29 more
core   +1 more source

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