Results 61 to 70 of about 35,580 (228)

Mass Spectrometry Imaging Combined With Single‐Cell Transcriptional Profiling Reveals the Multidimensional Spatial Distributions and Biosynthetic Pathways of Medicinal Components in Andrographis paniculata

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT The synthesis and accumulation of active ingredients in medicinal plants are distributed in specific organs, tissues, and cell types, which are important for the exploitation of medicinal plants. However, the fine distribution of active ingredients is difficult to know. Here, the system of mass spectrometry imaging (MSI) integrated with single‐
HaiSheng Zeng   +14 more
wiley   +1 more source

Clinical significance of exercise‐induced hypoalgesia in individuals with temporomandibular disorders and neck pain: A clinical trial protocol

open access: yesExperimental Physiology, EarlyView.
Abstract Evidence reports positive effects of neck motor control and aerobic exercises (AEs) to improve pain in individuals with temporomandibular disorders (TMD) and neck pain. A single bout of exercise typically leads to an increase in pain thresholds up to 30 min post‐exercise, known as exercise‐induced hypoalgesia (EIH).
Luiz Felipe Tavares   +5 more
wiley   +1 more source

The effectiveness of aerobic exercise on pain and disability in individuals with neck pain: A systematic review and meta‐analysis

open access: yesExperimental Physiology, EarlyView.
Abstract The present review aimed to investigate the effectiveness of aerobic exercise (AE) compared to other interventions in decreasing pain intensity and reducing disability in individuals with neck pain. A systematic review (SR) of randomized controlled trials was conducted. This SR was registered in PROSPERO (CRD42021231231).
Ana lzabela Sobral de Oliveira‐Souza   +9 more
wiley   +1 more source

Flavin Biosynthesis Enhances Extracellular Electron Transfer in Bioengineered Escherichia coli

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
Microbial electronics are promising for energy, sensing, environmental, and synthesis applications. E. coli are engineered with extracellular electron transfer (EET) pathways from a microbe that naturally produces current to enable bioelectronics based on E. coli.
Mohammed Mouhib   +4 more
wiley   +1 more source

Functionalized Donor–π–Acceptor (D–π–A) Organic Linkers for Metal–Organic Frameworks with Extended Visible‐Light Absorption

open access: yesChemistry–Methods, Volume 6, Issue 1, January 2026.
Triphenylamine‐based dyes L0‐TA and L1‐TA are synthesized and electrochemically characterized to assess their suitability for photocatalytic hydrogen production via water splitting. Crystallographic simulations confirm their structural compatibility with the MIL‐125 framework, allowing incorporation without steric clashes.
Giorgia Salerno   +6 more
wiley   +1 more source

Recent Developments in Capillary and Microchip Electroseparations of Peptides (2023–mid 2025)

open access: yesELECTROPHORESIS, Volume 47, Issue 1, Page 106-136, January 2026.
ABSTRACT This review presents a comprehensive overview of the developments and applications of high‐performance capillary and microchip electromigration methods (zone electrophoresis in a free solution or in sieving media, isotachophoresis, isoelectric focusing, affinity electrophoresis, electrokinetic chromatography, and electrochromatography) for ...
Václav Kašička
wiley   +1 more source

The Opioid System in Temporal Lobe Epilepsy: Functional Role and Therapeutic Potential

open access: yesFrontiers in Molecular Neuroscience, 2017
Temporal lobe epilepsy is considered to be one of the most common and severe forms of focal epilepsies. Patients often develop cognitive deficits and emotional blunting along the progression of the disease.
Johannes Burtscher, Christoph Schwarzer
doaj   +1 more source

Lipidomic Comparison of Detergent‐Soluble and Detergent‐Resistant Lipid Domains Isolated From Rat Cerebellum and the Effect of Hypoxia–Ischemia Using UPLC‐HDMSE

open access: yesJournal of Mass Spectrometry, Volume 61, Issue 1, January 2026.
ABSTRACT Hypoxic ischemic encephalopathy (HIE) due to insufficient oxygen or blood flow to the brain can result in inflammation, impaired neurodevelopment, or death. Changes to microdomain lipid composition may contribute to altered structure and function of key regulatory processes; however, knowledge regarding changes to membrane lipid composition ...
Samuel A. Krug   +4 more
wiley   +1 more source

Effects of Restraint Stress on Circulating Corticosterone and Met Enkephalin in Chickens: Induction of Shifts in Insulin Secretion and Carbohydrate Metabolism

open access: yesAnimals
This study examined the effects of acute restraint stress in the presence or absence of naltrexone on the circulating concentrations of insulin, glucose, Met-enkephalin and corticosterone in 14-week-old chickens [design: 2 sex × 2 stress/non-stress × 2 +/
Colin G. Scanes   +2 more
doaj   +1 more source

Molecular basis of domain‐specific angiotensin I‐converting enzyme inhibition by the antihypertensive drugs enalaprilat, ramiprilat, trandolaprilat, quinaprilat and perindoprilat

open access: yesThe FEBS Journal, Volume 293, Issue 2, Page 475-491, January 2026.
Inhibition of angiotensin I‐converting enzyme is an effective strategy for the treatment of hypertension. However, the clinically available ACE inhibitors cause side effects due to nonselective inhibition of the two catalytic domains of ACE (nACE and cACE).
Kyle S. Gregory   +3 more
wiley   +1 more source

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