Results 21 to 30 of about 33,942 (331)

Anti-Inflammatory Effect of Homo- and Heterodimers of Natural Enkephalinase Inhibitors in Experimental Colitis in Mice

open access: yesMolecules, 2020
Background: the pharmacological treatment and/or maintenance of remission in inflammatory bowel diseases (IBDs) is currently one of the biggest challenges in the field of gastroenterology.
Małgorzata Sobocińska   +3 more
doaj   +1 more source

Exposure to exogenous enkephalins disrupts reproductive development in the Eastern lubber grasshopper, Romalea microptera (Insecta: Orthoptera). [PDF]

open access: yesPLoS ONE, 2012
Enkephalins play a major role in reproductive physiology in crustaceans; however their role in reproductive development in insects is largely unknown. We investigated the effect of exposure to exogenous leucine-enkephalin (Leu-Enk), methionine-enkephalin
Sandeep Kumar   +4 more
doaj   +1 more source

Cellular Profiles of Prodynorphin and Preproenkephalin mRNA-Expressing Neurons in the Anterior Olfactory Tubercle of Mice

open access: yesFrontiers in Neural Circuits, 2022
The olfactory tubercle (OT) is a striatal region that receives olfactory inputs. mRNAs of prodynorphin (Pdyn) and preproenkephalin (Penk), precursors of dynorphins and enkephalins, respectively, are strongly expressed in the striatum. Both produce opioid
Ayako Maegawa   +9 more
doaj   +1 more source

‘Acetaldehyde‐enkephalins’: elucidation of the structure of the acetaldehyde adducts of methionine‐enkephalin and leucine‐enkephalin [PDF]

open access: yesFEBS Letters, 1980
The two major endogenous opioid pentapeptides, methionine-enkephalin and leucine-enkephalin [ 1,2] rapidly react with acetaldehyde, under very mild conditions, to give an ‘acetaldehyde-enkephalin’ adduct, referred to as ‘acetaldehyde-enkephalin [Met’] and ‘acetaldehyde-enkephalin [Leu”], respectively 231.
Summers, Michael C.   +2 more
openaire   +4 more sources

The effect of ethanol consumption on the carboxypeptidase E activity on different age rats posterity

open access: yesИзвестия высших учебных заведений. Поволжский регион: Естественные науки, 2022
Background. The consumption of ethanol by dams strongly effects the offspring’s body, its health both at birth and throughout life. This effect has a particularly strong effect on the functioning of various regulatory systems, in particular ...
A.N. Vernigora, N.V. Volkova
doaj   +1 more source

Delta opioid receptors on nociceptive sensory neurons mediate peripheral endogenous analgesia in colitis

open access: yesJournal of Neuroinflammation, 2022
Background Inflammatory visceral pain is endogenously controlled by enkephalins locally released by mucosal CD4+ T lymphocytes in mice. The present study aimed at identifying opioid receptor(s) expressed on nociceptive sensory nerves involved in this ...
Xavier Mas-Orea   +5 more
doaj   +1 more source

Opioid Receptors in Immune and Glial Cells-Implications for Pain Control [PDF]

open access: yes, 2020
Opioid receptors comprise μ (MOP), δ (DOP), κ (KOP), and nociceptin/orphanin FQ (NOP) receptors. Opioids are agonists of MOP, DOP, and KOP receptors, whereas nociceptin/orphanin FQ (N/OFQ) is an agonist of NOP receptors.
Celik, Melih Ö., Machelska, Halina
core   +1 more source

Neuroplasticity and Healthy Lifestyle: How Can We Understand This Relationship? [PDF]

open access: yes, 2017
Our brain has this extraordinary ability to experience functional and structural changes before environmental stimuli, cognitive demand, or our experience itself. Exercise, diet, an appropriate sleep pattern, and reading habits are among those activities
Begega, Azucena   +4 more
core   +3 more sources

Enkephalins in hematopoiesis

open access: yesBiomedicine & Pharmacotherapy, 1997
Recent data support the view that neuropeptide mediators, in particular opioid peptides, participate in the control of hematopoiesis. The main arguments are: neuropeptides modulate the functions of lymphoid cells, macrophages and mature granulocytes; they control cell proliferation and differentiation in many tissues, particularly during embryogenesis;
Jelka Gabrilovac   +4 more
openaire   +4 more sources

Opioids and Ocular Surface Pathology: A Literature Review of New Treatments Horizons [PDF]

open access: yes, 2022
This review discusses the role of opioids in the corneal surface and the different pathways and therapeutic methods of management. A literature review was performed using PubMed database.
García López, Celia   +4 more
core   +4 more sources

Home - About - Disclaimer - Privacy