Results 51 to 60 of about 12,769 (228)

Lyotropy as a Design Consideration for Ultra‐Small Protein Nanoparticles via Electrohydrodynamic Jetting

open access: yesMacromolecular Rapid Communications, EarlyView.
Lyotropic Ion‐Specific Effects Drive the Synthesis of Ultra‐Small Protein Nanoparticles via Electrohydrodynamic Jetting. ABSTRACT Protein‐based nanoparticles offer tailored bioactivity and biodegradability that are distinct from their synthetic polymeric counterparts.
Muhammad Haseeb Iqbal   +4 more
wiley   +1 more source

Influence of Mutations of Conserved Arginines on Neuropeptide Binding in the DPP III Active Site

open access: yesMolecules, 2023
Dipeptidyl peptidase III (DPP III), a zinc exopeptidase, is involved in the final steps of intercellular protein degradation and has a marked affinity for opioid peptides such as enkephalins and endomorphins.
Antonija Tomić   +2 more
doaj   +1 more source

Recent Advancements in the Characterization of D‐Amino Acid and Isoaspartate Post‐Translational Modifications

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT One of the great triumphs of mass spectrometry‐based peptide and protein characterization is the characterization of their modifications as most modifications have a characteristic mass shift. What happens when the modification does not change the mass of the peptide?
Samuel Okyem, Jonathan V. Sweedler
wiley   +1 more source

Anesthetic Mechanism of Myeloacupuncture in Joints аnd Spine Pathology

open access: yesBolʹ, Sustavy, Pozvonočnik, 2015
The article presents a literature review on the application of such method of reflexotherapy acupuncture as myeloacupuncture used in the pathology of the peri­pheral joints and spine.
V.V. Yakovlenko   +2 more
doaj   +1 more source

A drug delivery strategy: binding enkephalin to asialoglycoprotein receptor by enzymatic galactosylation. [PDF]

open access: yesPLoS ONE, 2014
Glycosylation of biopharmaceuticals can mediate cell specific delivery by targeting carbohydrate receptors. Additionally, glycosylation can improve the physico-chemical (drug-like) properties of peptide based drug candidates.
Michelle P Christie   +8 more
doaj   +1 more source

Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Huntington's disease (HD) is characterized by early, selective, progressive vulnerability of striatal medium spiny neurons (MSNs). Proenkephalin (PENK), a precursor of opioid peptides abundantly expressed in MSNs, is a promising biomarker of striatal integrity, but region‐specific associations and its potential for early‐stage ...
Mena Farag   +14 more
wiley   +1 more source

Enkephalins: Endogenous Analgesics with an Emerging Role in Stress Resilience

open access: yesNeural Plasticity, 2017
Psychological stress is a state of mental or emotional strain or tension that results from adverse or demanding circumstances. Chronic stress is well known to induce anxiety disorders and major depression; it is also considered a risk factor for ...
Mathilde S. Henry   +3 more
doaj   +1 more source

Expression of the Antimicrobial Peptide Piscidin 1 and Neuropeptides in Fish Gill and Skin: A Potential Participation in Neuro-Immune Interaction

open access: yesMarine Drugs, 2022
Antimicrobial peptides (AMPs) are found widespread in nature and possess antimicrobial and immunomodulatory activities. Due to their multifunctional properties, these peptides are a focus of growing body of interest and have been characterized in several
Giacomo Zaccone   +15 more
doaj   +1 more source

N‐Geranylated Amino Acid Surfactants with Low Critical Micelle Concentrations from Abundant, Naturally Derived Starting Materials

open access: yesChemistryOpen, EarlyView.
Cleaning Up Surfactants: Realising critical micelle concentrations lower than sodium dodecyl sulfate with sustainable surfactants prepared from amino acids and naturally occurring aldehydes. In this work, a simple method for the preparation of N‐alkylated amino acid surfactants in 1–2 steps is reported.
Brett L. Pollard   +3 more
wiley   +1 more source

Quality Control Strategies for Differentiation of Kalanchoe Species

open access: yesPhytochemical Analysis, EarlyView.
ABSTRACT Kalanchoe species products are commercially available in local markets and by internationally accessible online retailers and may exhibit quality issues because of misidentification from similar common names and anatomical similarities among related species used as feedstock. This study proposes an approach using UPLC‐MS/MSE and HPTLC, coupled
Evelyn A. de Andrade   +8 more
wiley   +1 more source

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