Results 161 to 170 of about 2,166 (197)

In vitro phase I metabolism of the depsipeptide enniatin B

Analytical and Bioanalytical Chemistry, 2011
The enniatins are a group of more than 20 cyclic depsipeptides from fungi with numerous biological effects. Enniatin B is commonly one of the principal analogues in species of the genus Fusarium, known to have ionophoric, antibiotic and insecticidal activity. In the present study, enniatin B was incubated with rat, dog and human liver microsomes.
Lada, Ivanova, Christiane Kruse, Faeste, Silvio, Uhlig   +2 more
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A molecular orbital study on the conformation of enniatin B

Biochemical and Biophysical Research Communications, 1973
Abstract Molecular orbital calculations using the PCILO method are performed on the conformation of the symmetrical form of enniatin B. The values of the Φ and ψ angles found for the preferred conformation agree closely with the results of X-ray study of the K + complex of enniatin B.
B, Maigret, B, Pullman
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Antifungal effects of the bioactive compounds enniatins A, A1, B, B1

Toxicon, 2010
To produce enniatin (ENs), Fusarium tricinctum CECT 20150 was grown in a liquid medium of potato (PDB), being mycotoxin purified by high performance liquid chromatography (HPLC) with a reverse phase semipreparative column using a mobile phase of acetonitrile/water using gradient condition. The purity of the ENs fractions was verified by analytical HPLC
Meca G., Soriano J. M., Gaspari A., RITIENI, ALBERTO, Moretti A., Mañes J.   +5 more
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Interaction effects of enniatin B, deoxinivalenol and alternariol in Caco-2 cells

Toxicology Letters, 2016
Enniatin B (ENN B), deoxinivalenol (DON) and alternariol (AOH) are secondary metabolites of filamentous fungi. These mycotoxins are contaminants of vegetables and cereals. They are cytotoxic and their effects are enhanced by their mixtures. The objectives of this study were to compare the cytotoxicity of ENN B, DON and AOH alone or in combination in ...
Celia, Fernández-Blanco, Guillermina, Font, Maria-Jose, Ruiz   +2 more
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Topochemical Approach in Studies of the Structure–Activity Relation: Enantio-enniatin B

Nature, 1967
THE interaction of a biologically active substance with a selective receptor (for instance, substrate and enzyme) to cause a certain physiological effect is chemically complex, requiring not only a certain minimum of steric congruity of the molecules but also a given electron density distribution in the interacting functional centres.
M M, Shenyakin, Y A, Ovchinnikov, V T, Ivanov, A V, Evstratov   +3 more
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Enniatin B and Valinomycin as Ion Carriers: An Empirical Force Field Analysis

Journal of Biomolecular Structure and Dynamics, 1984
The alkali-ion binding properties of two natural depsipeptide ion carriers, enniatin B (EnB) and valinomycin (VM), are examined and compared by the empirical force field method. While VM has been shown to bind preferentially K+, Rb+, and Cs+ over Na+ in most solvents, EnB is considerably less specific.
S, Lifson, C E, Felder, A, Shanzer
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Production of type A trichothecenes and enniatin B byFusarium sambucinum Fuckel sensu lato

Mycopathologia, 1995
Twenty-nine Fusarium isolates, representing three new taxa originated by Nirenberg from F. sambucinum Fuckel sensu lato, namely: F. sambucinum Fuckel sensu stricto, F. venenotum Nirenb., and F. torulosum (Berk. & Curt.) Nirenb., were tested for in vitro production of toxic secondary metabolites on autoclaved corn kernels. F.
C Altomare, A Logrieco, A Bottalico, G Mulé, A Moretti, A Evidente   +5 more
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Enniatin B-induced cell death and inflammatory responses in RAW 267.4 murine macrophages

Toxicology and Applied Pharmacology, 2012
The mycotoxin enniatin B (EnnB) is predominantly produced by species of the Fusarium genera, and often found in grain. The cytotoxic effect of EnnB has been suggested to be related to its ability to form ionophores in cell membranes. The present study examines the effects of EnnB on cell death, differentiation, proliferation and pro-inflammatory ...
Gammelsrud, A., Solhaug, A., Dendelé, Béatrice, Sandberg, W. J., Ivanova, L., Kocbach Bølling, A., Lagadic-Gossmann, Dominique, Refsnes, M., Becher, R., Eriksen, G., Holme, J. A.   +10 more
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Welkstoffe und Antibiotika. 8. Mitteilung. Über die Konstitution von Enniatin B

Helvetica Chimica Acta, 1948
AbstractDie Konstitution von Enniatin B (C22H38O6N2), eines aus Fusariam Stamm ETH 4363 und Stamm ETH 1674 isolierten Antibiotikums, wurde aufgeklärt. Die same Hydrolyse liefert 2 Mol N‐Methyl‐( + )‐valin (111) und 2 Mo1 D‐α‐Oxy‐isovaleriansäure (11), wäihrend bei der alkalischen Hydrolyse das D‐α‐Oxy‐isovaleryl‐N‐methyl‐(+)‐valin (IV) neben dem ...
Pl. A. Plattner, U. Nager
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Cytotoxicity of enniatins A, A1, B, B1, B2 and B3 from Fusarium avenaceum

Toxicon, 2006
The enniatins A, A1, B, B1, B2 and B3 were purified from hexane-extracts of Fusarium avenaceum rice cultures, using semi-preparative HPLC, after precipitation of lipids. Their toxicity, as well as the toxicity of the related fungal metabolite beauvericin (Bea) and the trichothecenes deoxynivalenol (DON) and T-2 toxin, was tested in two cell lines of ...
Lada, Ivanova, Eystein, Skjerve, Gunnar S, Eriksen, Silvio, Uhlig   +3 more
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