Results 11 to 20 of about 9,100 (154)

Liver Transplantation for HBV-Related Disease in France: NUC Type Before LT Is Associated With Patient Survival. [PDF]

Liver Int
ABSTRACT Background & Aims Liver transplantation (LT) is indicated for liver complications related to hepatitis B virus (HBV) infection: acute liver failure (ALF), decompensated cirrhosis or hepatocellular carcinoma (HCC). The present study aimed to describe and evaluate patient survival after LT for HBV‐related disease in France and identify the ...
Bienvenue I, Roux O, Coilly A, Abergel A, Antonini T, Artzner T, Boillot O, Chermak F, Conti F, Dharancy S, Duvoux C, Elkrief L, Farrugia M, Francoz C, Giguet B, Hardwigsen J, Houssel-Debry P, Hilleret MN, Kamar N, Latournerie M, Meszaros M, Radenne S, Roche B, Salamé E, Verhoeven-Weil D, Samuel D, Zoulim F, Dumortier J, Villeret F.   +28 more
europepmc   +2 more sources

Impact of tenofovir vs. entecavir treatment on progression of chronic hepatitis B: A nationwide cohort study [PDF]

JHEP Reports
Background & Aims: Conflicting evidence exists on hepatocellular carcinoma (HCC) risk in patients with chronic hepatitis B (CHB) receiving tenofovir vs. entecavir.
Wan-Jung Wu, Wen-Jie Liu, Chih-Lin Lin, Chun-Jen Liu, Yi-Wen Huang, Jui-Ting Hu, Ming-Whei Yu   +6 more
doaj   +2 more sources

Comparative analysis of tenofovir alafenamide and entecavir on renal function and serum lipids in liver transplant recipients: a controlled retrospective cohort study [PDF]

BMC Gastroenterology
Background Antiviral treatments can impact serum lipids as well as kidney function. We conducted a retrospective observational study with a 48-month follow-up period, involving liver transplant recipients receiving either entecavir or tenofovir ...
Hüseyin Döngelli, Nilay Danış, Tarkan Ünek, Tufan Egeli, Cihan Ağalar, Mücahit Özbilgin, Hülya Ellidokuz, Mesut Akarsu   +7 more
doaj   +2 more sources

Treatment with the Immunomodulator AIC649 in Combination with Entecavir Produces Antiviral Efficacy in the Woodchuck Model of Chronic Hepatitis B

Viruses, 2021
As current interventions for chronic hepatitis B (CHB) rarely induce cure, more effective drugs are needed. Short-term treatment of woodchucks with the novel immunomodulator AIC649, a parapoxvirus-based stimulator of toll-like receptor 9 dependent and ...
Kyle E. Korolowicz, Manasa Suresh, Bin Li, Xu Huang, Changsuek Yon, Xuebing Leng, Bhaskar V. Kallakury, Robin D. Tucker, Stephan Menne   +8 more
doaj   +1 more source

“Black box warning” rash with entecavir - case report

BMC Gastroenterology, 2020
Background Hepatitis B infection is a significant worldwide health issue, predispose to the development of liver cirrhosis and hepatocellular carcinoma.
Xiong Khee Cheong, Zhiqin Wong, Norazirah Md Nor, Bang Rom Lee   +3 more
doaj   +1 more source

Impact of HBcrAg levels on HBsAg seroconversion after HBV rebound: a case report

Journal of Pharmaceutical Health Care and Sciences, 2023
Background Nucleoside analogues (NAs) such as entecavir are required for at least 12 months when patients with resolved hepatitis B virus (HBV) infection develop HBV reactivation.
Maki Ohkubo, Kuniaki Fukuda, Shigeru Chiba, Masato Homma   +3 more
doaj   +1 more source

Analysis of minimum target prices for production of entecavir to treat hepatitis B in high- and low-income countries

Journal of Virus Eradication, 2015
Background: In 2013, an estimated 686,000 people died from hepatitis B virus (HBV) infection worldwide. Mass treatment programmes for hepatitis B will require very low drug costs.
Andrew Hill, Dzintars Gotham, Graham Cooke, Sanjay Bhagani, Isabelle Andrieux-Meyer, Jennifer Cohn, Joseph Fortunak   +6 more
doaj   +1 more source

Total Synthesis of Entecavir [PDF]

The Journal of Organic Chemistry, 2013
Entecavir (BMS-200475) was synthesized from 4-trimethylsilyl-3-butyn-2-one and acrolein. The key features of its preparation are: (i) a stereoselective boron-aldol reaction to afford the acyclic carbon skeleton of the methylenecylopentane moiety; (ii) its cyclization by a Cp2TiCl-catalyzed intramolecular radical addition of an epoxide to an alkyne; and
Velasco Turbau, Javier, Ariza Piquer, Xavier, Badía, Laura, Bartra Sanmartí, Martí, Berenguer, Ramon, Farràs i Soler, Jaume, Gallardo, Joan, García Gómez, Jordi, Gasanz, Yolanda   +8 more
openaire   +3 more sources

The Comparative Efficacy and Safety of Entecavir and Lamivudine in Patients with HBV-Associated Acute-on-Chronic Liver Failure: A Systematic Review and Meta-Analysis

Gastroenterology Research and Practice, 2016
Background. Currently, both of entecavir and lamivudine are effective for patients with HBV-associated acute-on-chronic liver failure (ACLF). However, there is no consensus on the efficacy of entecavir versus lamivudine for patients with HBV-associated ...
Jiao Yang, Hang Sun, Qi Liu
doaj   +1 more source

Comparison of first-year results of tenofovir and entecavir treatments of nucleos(t)ide-naive chronic hepatitis B patients with hepatosteatosis

The Saudi Journal of Gastroenterology, 2015
Background/Aim: Hepatic steatosis may influence the response to antivirals in chronic hepatitis B patients. This study aimed to compare the efficacy of entecavir and tenofovir in nucleos(t) ide-naive chronic hepatitis B patients with hepatosteatosis ...
Zeynal Dogan, Levent Filik, Bilal Ergül, Murat Sarikaya   +3 more
doaj   +1 more source