Results 41 to 50 of about 4,026 (142)

Auxiliary Liver Graft Can Be Protected From HBV Infection in HBsAg Positive Blood Circulation

Frontiers in Medicine, 2021
Auxiliary grafts have a high risk of Hepatitis B virus (HBV) infection in patients with chronic HBV-related diseases. Hepatitis B virus-related auxiliary partial orthotopic liver transplantation (APOLT) cases were reviewed to show the results of current ...
Lin Wei, Lin Wei, Lin Wei, Hai-Ming Zhang, Hai-Ming Zhang, Hai-Ming Zhang, Chi-Dan Wan, Wei Qu, Wei Qu, Wei Qu, Zhi-Gui Zeng, Zhi-Gui Zeng, Zhi-Gui Zeng, Ying Liu, Ying Liu, Ying Liu, Jun Xiong, Li-Ying Sun, Li-Ying Sun, Li-Ying Sun, Zhi-Jun Zhu, Zhi-Jun Zhu, Zhi-Jun Zhu   +22 more
doaj   +1 more source

Recompensation of Cirrhosis: A New Treatment‐Related Disease State

Portal Hypertension &Cirrhosis, EarlyView.
This perspective article conceptualizes recompensation of cirrhosis as a distinct treatment‐related disease state rather than mere transient clinical improvement after etiology‐directed therapy, and further proposes a four‐state classification including compensated cirrhosis, stable recompensation, unstable recompensation, and persistent decompensation
Wentao Tan, Zhiying He, Shuai Xia, Luqi Tang, Hong You, Bingqiong Wang   +5 more
wiley   +1 more source

A case of gynecomastia due to entecavir.

, 2010
Hepatitis B is an important health problem all over the world as well as in our country. Entecavir is a nucleoside analog used in the treatment of chronic hepatitis B.
Dabak, Resat, Emel AHISHALI, Ahishali, Emel, Oya Uygur BAYRAMICLI, Oznur AK, Resat DABAK, Can DOLAPCIOGLU, AK, ÖZNUR, Dolapcioglu, Can, Bayramicli, Oya Uygur   +9 more
core   +1 more source

The Emerging Role of China in the Innovation, Individualization, and Translation of Antiviral Therapeutics for Chronic Hepatitis B

Portal Hypertension &Cirrhosis, EarlyView.
This perspective outlines China's contributions toward functional‐cure‐oriented antiviral therapies for chronic hepatitis B, summarizing key clinical data on bepirovirsen and domestic drug pipelines with balanced coverage of both promising and disappointing trial results.
Dandan Weng, Zhujun Cao, Qing Xie
wiley   +1 more source

Release mechanism and pharmacodynamics of entecavir micro spheres

Pakistan Journal of Pharmaceutical Sciences
Entecavir, an effective anti-hepatitis B drug with low resistance rate, was designed as sustained-release micro spheres in our previous study. Here, we aimed to reveal the drug-release mechanism by observing the drug distribution and degradation behavior
Chunyan Zhang, Liuxiang Chu, Keke Li, Maocai Yan   +3 more
doaj   +1 more source

Effectiveness and Safety of Vunakizumab Over 12 Weeks in Chinese Patients With Plaque Psoriasis: A Prospective, Real‐World Cohort Study

The Journal of Dermatology, EarlyView.
ABSTRACT Vunakizumab is a humanized anti‐IL‐17A monoclonal antibody approved in China for moderate‐to‐severe plaque psoriasis. Real‐world data on its effectiveness and predictors of response remain scarce. This prospective, single‐center, observational study enrolled 34 adults receiving vunakizumab (240 mg subcutaneously at weeks 0, 2, and 4, then ...
Tong Wu, Esmeraldito Ferreira, Guang‐Yu Peng, Zi‐Yi Fu, Yong‐Feng Chen   +4 more
wiley   +1 more source

Stepwise process for the development of entecavir resistance in a chronic hepatitis B virus infected patient.: Mechanism of entecavir resistance

, 2007
International audienceBACKGROUND/AIMS: Complex mutants may be selected under sequential anti-VHB pressures. We analyzed the genotypic and phenotypic evolution of the viral quasi-species of a patient who developed resistance to entecavir following ...
Christian Trépo, Ollivet, Aurélie, Luc Barraud, Zoulim, Fabien, Christian Pichoud, Stéphanie Villet, Villet, Stéphanie, Villeneuve, Jean-Pierre, Pichoud, Christian, Barraud, Luc, Jean-Pierre Villeneuve, Fabien Zoulim, Trépo, Christian, Aurélie Ollivet   +13 more
core   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Baseline hepatitis B surface antigen quantitation can predict virologic response in entecavir-treated chronic hepatitis B patients

Journal of the Formosan Medical Association, 2014
Several anti-viral drugs are approved for the treatment of hepatitis B virus (HBV) infection. However, whether quantitative hepatitis B surface antigen (qHBsAg) can predict the therapeutic response during long-term entecavir treatment remains unclear ...
Chia-Chi Wang, Tai-Chung Tseng, Pin-Chao Wang, Hans Hsienhong Lin, Jia-Horng Kao   +4 more
doaj   +1 more source

Carriage of the Laboratory of Genetics and Physiology Protein 2 Q425R Variant Reduces Liver Disease Severity in European Patients With Chronic Hepatitis Delta

Alimentary Pharmacology &Therapeutics, EarlyView.
In patients with chronic hepatitis Delta, the LGP2 Q425R variant (rs2074158 CC/CT genotypes), associated with an enhanced interferon response in vitro, becomes progressively less frequent as liver disease advances from no cirrhosis to cirrhosis, and to cirrhosis with progressive increase of portal hypertension evaluated by thrombocytopenia.
Sara Cmet, Elisabetta Degasperi, Annarosa Cussigh, Elisabetta Fontanini, Maria Paola Anolli, Floriana Facchetti, Riccardo Perbellini, Dana Sambarino, Sara Colonia Uceda Renteria, Annapaola Callegaro, Davide Bitetto, Elisa Fumolo, Ezio Fornasiere, Elena Garlatti Costa, Edmondo Falleti, Pietro Lampertico, Pierluigi Toniutto   +16 more
wiley   +1 more source