Results 21 to 30 of about 4,026 (142)
Impact of HBcrAg levels on HBsAg seroconversion after HBV rebound: a case report
Journal of Pharmaceutical Health Care and Sciences, 2023 Background Nucleoside analogues (NAs) such as entecavir are required for at least 12 months when patients with resolved hepatitis B virus (HBV) infection develop HBV reactivation.
Maki Ohkubo +3 more
doaj +1 more source
Journal of Virus Eradication, 2015 Background: In 2013, an estimated 686,000 people died from hepatitis B virus (HBV) infection worldwide. Mass treatment programmes for hepatitis B will require very low drug costs.
Andrew Hill +6 more
doaj +1 more source
Total Synthesis of Entecavir [PDF]
The Journal of Organic Chemistry, 2013 Entecavir (BMS-200475) was synthesized from 4-trimethylsilyl-3-butyn-2-one and acrolein. The key features of its preparation are: (i) a stereoselective boron-aldol reaction to afford the acyclic carbon skeleton of the methylenecylopentane moiety; (ii) its cyclization by a Cp2TiCl-catalyzed intramolecular radical addition of an epoxide to an alkyne; and
Velasco Turbau, Javier +8 more
openaire +3 more sources
Gastroenterology Research and Practice, 2016 Background. Currently, both of entecavir and lamivudine are effective for patients with HBV-associated acute-on-chronic liver failure (ACLF). However, there is no consensus on the efficacy of entecavir versus lamivudine for patients with HBV-associated ...
Jiao Yang, Hang Sun, Qi Liu
doaj +1 more source
The Saudi Journal of Gastroenterology, 2015 Background/Aim: Hepatic steatosis may influence the response to antivirals in chronic hepatitis B patients. This study aimed to compare the efficacy of entecavir and tenofovir in nucleos(t) ide-naive chronic hepatitis B patients with hepatosteatosis ...
Zeynal Dogan +3 more
doaj +1 more source
Frontiers in Oncology, 2023 ObjectiveIn this study, we aimed to perform a network meta-analysis to compare the effectiveness of NAs in decreasing the reactivation of HBV, reducing chemotherapy disruption, and improving survival in oncology patients.MethodsRelevant randomized ...
Yuqing Zhao +12 more
doaj +1 more source
Molecules, 2023 Bentysrepinine (Y101) is a novel phenylalanine dipeptide for the treatment of hepatitis B virus. Renal excretion played an important role in the elimination of Y101 and its metabolites, M8 and M9, in healthy Chinese subjects, although the molecular ...
Aijie Zhang +13 more
doaj +1 more source
A novel estimation of the relative economic value in terms of different chronic hepatitis B treatment options. [PDF]
PLoS ONE, 2013 BACKGROUND: Prescribers, payors and healthcare decision-makers are increasingly examining the value of treatments. This study aims at analyzing economic value of chronic hepatitis B (CHB) treatment options, which are available in Korea.
Jun Yong Park +8 more
doaj +1 more source
Beni-Suef University Journal of Basic and Applied Sciences, 2022 Background A meta-analysis was made to assess the impact of entecavir comparison with tenofovir disoproxil fumarate as nucleos(t)ide analogue on hepatic cellular carcinoma (HCC). The study had subjects with chronic hepatitis B virus (HBV).
Sara M. Tony +3 more
doaj +1 more source
Revisiting HBV resistance to entecavir with a phenotypic approach
, 2020 International audienceTreatment adaptation after hepatitis B virus (HBV) treatment failure relies on genotypic resistance testing. However, the results of such tests are not always consistent with treatment response.
Lefeuvre, Sandrine +13 more
core +1 more source