Results 61 to 70 of about 4,026 (142)

Chronic hepatitis B and hematological malignancies

Клиническая онкогематология, 2013
The active usage of monoclonal antibodies in therapy for hematology malignancies made reactivation of hepatitis B virus (HBV) infection one of the major health problems. Monoclonal antibodies are also used in solid tumors, rheumatic, gastroenterological,
A. O. Buyeverov, P. O. Bogomolov
doaj   +1 more source

Machine Learning and Structural Analysis for Generation‐Wise Selection of Perylene Diimide Dendrimers Based on Topological Compatibility With Drug Molecules

ChemistryOpen, Volume 15, Issue 11, November 2026.
Machine learning and graph‐theoretic descriptors are integrated to evaluate topology‐based compatibility between perylene diimide‐core dendrimer generations and antiviral, antioxidant, and imaging agents. Standardized structural similarity reveals generation‐dependent compatibility patterns, while Gaussian process regression uncovers key structure ...
Zainab Bibi, Jabbar Ali, Sana Irshad, Muhammad Saad Ghafar, Yasir Ali, Yilun Shang   +5 more
wiley   +1 more source

Sequential therapy using lamivudine in entecavir-treated patients with undetectable HBV DNA–results at 48 weeks

, 2009
Background: The aim of this study was to determine the efficacyof entecavir-lamivudine sequential therapy in patients withundetectable viral load and normal ALT after initial entecavirtreatment.
Fung, JYY, Cheng, CTK, Yuen, RMF, Lai, CL, Yuen, JCH, Wu, CH   +5 more
core   +1 more source

Switching to Tenofovir Therapy Versus Continuation of Entecavir for Patients With Hepatitis B Virus Infection: A Systematic Review and Meta‐Analysis

JGH Open
Background Hepatitis B virus (HBV) infection causes liver disease, including hepatocellular carcinoma. Controlling viral activity is crucial to reducing complications.
Muhammad Shahzil, Ammad Javaid Chaudhary, Talha Kashif, Ali Akram Qureshi, Anza Muhammad, Faiza Khan, Muhammad Saad Faisal, Muhammad Ali Khaqan, Hassam Ali, Yara Dababneh, Dilip Moonka   +10 more
doaj   +1 more source

HBV-INFECTION DE NOVO AFTER ORTHOTOPIC LIVER TRANSPLANTATION: CLINICAL AND VIROLOGICAL CHARACTERISTICS, ASSESSMENT OF ANTIVIRUS THERAPY EFFECTIVENESS

Вестник трансплантологии и искусственных органов, 2012
We studied 11 cases of HBV-infection de novo in patients after orthotopic liver transplantation performed because of non-viral cirrhosis. Serum НBeAg, was revedled in all patients. In most cases clinical course of HBV-infection was benign. Treatment with
O. I. Malomuzh, E. V. Chekletsova, X. M. Кhizroyev, V. A. Pets, S. V. Fokin, V. A. Taranov, O. M. Tsirulniкova, S. V. Gautier   +7 more
doaj   +1 more source

Transplantation of Hepatitis B Surface Antigen Positive or Viremic Kidneys: A Systematic Review and Meta‐Analysis

Clinical Transplantation, Volume 40, Issue 11, November 2026.
ABSTRACT Purpose This systematic review and meta‐analysis examines the evidence related to the use of HBV positive kidneys into non‐viremic kidney transplant recipients (KTRs). Methods We searched PubMed and Embase through November 2025 and identified studies of recipients of hepatitis B surface antigen positive (HBsAg+) or viremic kidneys.
Dhruv Ahuja, Beatrice P. Concepcion, Yuhong Yuan, Rachel Forbes, James L. Rogers, Helen S. Te, Yvonne El Kassis   +6 more
wiley   +1 more source

LIVER TRANSPLANTATION AND HBV INFECTION

Вестник трансплантологии и искусственных органов, 2009
The paper describes the modern approaches in treatment of hepatitis B virus (HBV)-infected patients who underwent liver transplantation. The patients with HBV liver cirrhosis and waiting for orthotopic liver transplantation (OLT) have to receive long ...
O. I. Andreytseva, A. V. Kozlova, V. E. Sutkin   +2 more
doaj   +1 more source

Safety, Tolerability and Antiviral Activity of GST‐HG131 in Chronic Hepatitis B: A Randomized, Double‐Blind Phase IIa Study

Liver International, Volume 46, Issue 11, November 2026.
ABSTRACT Background and Aims Chronic hepatitis B (CHB) remains a major global health burden. Current therapies rarely achieve a functional cure due to low rates of HBsAg clearance, the persistence of the viral replication template—covalently closed circular DNA (cccDNA)—and the need for lifelong treatment.
Yuming Guo, Zhe Xu, Yuanyuan Li, John Mao, Tianxiang Zhang, Yonggang Li, Fanping Meng, Junliang Fu, Dong Ji, Yingjie Ji, Yongqian Cheng, Min Zhang, Xin Zhang, Ying Sun, Zuxiong Huang, Dachuan Cai, Wenqiang Wu, Wenhao Yan, Xiuping Yan, Guoping Li, Jinlin Hou, George Zhang, Fu‐Sheng Wang   +22 more
wiley   +1 more source

Update on entecavir in the management of severe forms of Hepatitis B

, 2012
Rodolfo SaccoDepartment of Gastroenterology, Pisa University Hospital, Pisa, ItalyAbstract: Despite the effective management of most cases of hepatitis B virus (HBV) infection, there is still much room for improvement in the treatment of more severe ...
Sacco R
core  

Medicinal Chemistry Aspects of Thiazole and Thiazolidine Derivatives as Fundamental Building Blocks to Design New NNRTIs Against HIV‐1 Reverse Transcriptase

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
HIV‐1 reverse transcriptase (HIV‐1 RT) is a polymerase enzyme and a key target in HIV‐1 therapy. The discovery of selective HIV‐1 RT inhibitors has highlighted thiazole scaffolds and their derivatives, thiazolidine‐2‐one and thiazolidine‐2,4‐dione, as promising structures for the rational design of novel non‐nucleoside reverse transcriptase inhibitors (
José Arion da Silva Moura, Matheus Vinicius Guimarães de Melo, Diane Regis Santos do Nascimento, Thaynara Paula Warren Bezerra, Mathieu Métifiot, Patricia Recordon‐Pinson, Maira Galdino da Rocha Pitta, Marina Galdino da Rocha Pitta, Michelly Cristiny Pereira, Marie‐Line Andreola   +9 more
wiley   +1 more source