Results 131 to 140 of about 28,778 (289)

Establishing the reference broth microdilution MIC method for cefepime-taniborbactam

Journal of Clinical Microbiology
The investigational β-lactam/β-lactamase inhibitor combination cefepime-taniborbactam is intended as therapy for serious infections caused by Gram-negative pathogens resistant to third-generation cephalosporins and carbapenems.
Adam Belley, Susan M. Cusick, Dan C. Pevear, Laura Koeth, Jeanna DiFranco-Fisher, Nimmi Kothari, Stephen Hawser, Greg Moeck   +7 more
doaj   +1 more source

Mortality Risk Factors and Prognostic Analysis of Patients with Multi-Drug Resistant Enterobacterales Infection

Infection and Drug Resistance, 2022
Xinchun Wang,1,* Qi Li,2,* Jianbang Kang,1 Donghong Yin,1 Xiaoxia Li,1 Shuyun Wang,1 Qian Guo,1 Yan Song,1 Jing Wang,1 Jinju Duan1 1Department of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, People’s Republic of China ...
Wang X, Li Q, Kang J, Yin D, Li X, Wang S, Guo Q, Song Y, Wang J, Duan J   +9 more
doaj  

The Role of Neonatal Ward Environment as a Reservoir for the Dissemination of Multidrug‐Resistant Klebsiella pneumoniae in Algeria

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Whole‐genome sequencing of multidrug‐resistant Klebsiella pneumoniae from a neonatal ward environment in Chlef revealed persistent resistance genes and the clonal spread of high‐risk ST13. These findings highlight the hospital environment as a potential reservoir for transmission of resistant K. pneumoniae.
Meriem Derkaoui, Martin Alexander Fischer, Mohammed Sebaihia, Rachida Namoune, Fatiha Bouheudjeur, Meryem Beloukarif, Bakhta Madaoui, Bruno Silvester Lopes   +7 more
wiley   +1 more source

In vitro antibacterial activity of tigecycline against multidrug-resistant bacteria isolated at the Sourô Sanou University teaching hospital in Bobo-Dioulasso, Burkina Faso

African Journal of Laboratory Medicine
Background: Tigecycline, an antibiotic effective against multidrug-resistant bacteria (MDRB), remains inaccessible in Burkina Faso’s hospitals for urgent care. Given the resulting therapeutic challenges and mortality in emergency services, evidence-based
Odilon D. Kaboré, Mélissa J. Gonfouli, Merci Muhigwa, Abdourahmane Sow, Fernand Michodigni, André Nagalo, Jacques Zoungrana, Arsène Hema, Augustin Konkobo, Hervé Kafando, Adama Ouattara, Armel Poda, Sylvain Godreuil, Abdoul-Salam Ouedraogo   +13 more
doaj   +1 more source

Pharmacokinetic Analysis of Intravenous Push Cefepime in Critically Ill Patients With Sepsis

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 6, June 2026.
ABSTRACT Background Intravenous push (IVP) administration of cefepime increases ease of preparation and limits the need for small volume parenterals. The data on IVP pharmacokinetic/pharmacodynamic (PK/PD) parameters are limited, but may be especially relevant in critically ill patients with altered PK/PD for time‐dependent antibiotics like cefepime ...
Susan E. Smith, Rehana Bagodiya, Phuong Luong, Sakshi Shinde, Christopher M. Bland, Christopher Barry, Michael G. Bartlett, Nicholas R. Fox, Trisha N. Branan   +8 more
wiley   +1 more source

Forces Shaping Diversity of Hydrogen Peroxide Detoxification Potential in Ocean Microbial Ecosystems

Environmental Microbiology, Volume 28, Issue 6, June 2026.
Marine microbes which lack catalases, like Prochlorococcus, depend on ‘helpers’, like catalase‐positive Alteromonas, for hydrogen peroxide detoxification. Our results indicate diverse and distinct distributions of catalases (katG, katE and manganese catalase) among community members.
Hannah Goldberg, Sonya T. Dyhrman, Michelle A. DeMers, Rogier Braakman, Gwenn M. M. Hennon   +4 more
wiley   +1 more source

Interplay of Diet, Heat Stress, and the Microbiome Shapes Health and Escape Behaviour in Amphibian Larvae

Environmental Microbiology, Volume 28, Issue 6, June 2026.
Diet and temperature jointly shape the gut microbiome and host performance in amphibian larvae. In a multifactorial experiment with Rana temporaria, diet quality, rearing temperature, and heatwave exposure altered microbial communities and predicted metabolic pathways, while host health remained largely stable, suggesting microbiome plasticity and ...
Paula C. Eterovick, Julian Glos, Franziska Burkart, Jörg Overmann, Katharina Ruthsatz   +4 more
wiley   +1 more source

Antimicrobial susceptibilities of clinical bacterial isolates from urinary tract infections to fosfomycin and comparator antibiotics determined by agar dilution method and automated micro broth dilution

Microbiology Spectrum
Uncomplicated bacteremic urinary tract infections (bUTIs) are common, often caused by Escherichia coli, Klebsiella pneumoniae, and Enterococcus faecalis, with most encounters treated empirically.
Jamie L. Dombach, Nancy C. Smith, Teresa Kottiri, Alicia M. Schiller, Edwin Kamau   +4 more
doaj   +1 more source

Carriage of third-generation cephalosporin-resistant and carbapenem-resistant Enterobacterales among children in sub-Saharan Africa: a systematic review and meta-analysis

EClinicalMedicine
Summary Background The increasing resistance of Enterobacterales to third-generation cephalosporins and carbapenems in sub-Saharan Africa (SSA) is a major public health concern.
Micaela Ruef, S. Emonet, Arnaud Merglen, J. E. Dewez, B. Obama, Gaud Catho, Diego O. Andrey, Morgane Kowalski, S. Harbarth, C. Combescure, Noemie Wagner, Annick Galetto-Lacour   +11 more
semanticscholar   +1 more source

Changes in DOM Quality Determine Prokaryotic Activities and Extracellular Release in the NW Mediterranean Sea: An Experimental Approach

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Changes in DOM composition influence prokaryotic species growth in the Mediterranean Sea, shaping their metabolic responses and organic matter processing. In our study, higher DOP consumption and alkaline phosphatase activity led to the accumulation of recalcitrant DOM, highlighting how microbial community shifts drive distinct pathways in carbon ...
Eva Ortega‐Retuerta, Nawal Bouchachi, Rebeca Campos, Olivier Crispi, Barbara Marie, Charles‐Hubert Paulin, Karine Escoubeyrou, Jonathan Colombet, Telesphore Sime‐Ngando, Anabel Von Jackowski   +9 more
wiley   +1 more source