Results 131 to 140 of about 603,469 (215)

Characterizing Apixaban Pharmacokinetics Through Physiologically-Based Pharmacokinetic Modeling: Critical Role of Biliary Secretion and Enterohepatic Circulation in Humans. [PDF]

CPT Pharmacometrics Syst Pharmacol
Tsuchitani T, Kou W, Tomi M, Sugiyama Y.
europepmc   +1 more source

Use of human tissue stem cell-derived organoid cultures to model enterohepatic circulation.

Am J Physiol Gastrointest Liver Physiol, 2021
Blutt SE, Crawford SE, Bomidi C, Zeng XL, Broughman JR, Robertson M, Coarfa C, Tessier MEM, Savidge T, Hollinger FB, Curley SA, Donowitz M, Estes MK.   +12 more
europepmc   +1 more source

Population pharmacokinetics of regorafenib in solid tumours: Exposure in clinical practice considering enterohepatic circulation and food intake. [PDF]

Br J Clin Pharmacol, 2020
Keunecke A, Hoefman S, Drenth HJ, Zisowsky J, Cleton A, Ploeger BA.   +5 more
europepmc   +1 more source

Regulatory effects of Sini-San on bile acid homeostasis in the enterohepatic circulation of mice with liver fibrosis. [PDF]

Chin Med
Zhu F, Ding Y, Chen L, Fang R, Huang C, Liu E, Wang Y, Su Y, Ge C.   +8 more
europepmc   +1 more source

Lactobacillus delbrueckii Interfere With Bile Acid Enterohepatic Circulation to Regulate Cholesterol Metabolism of Growing-Finishing Pigs via Its Bile Salt Hydrolase Activity. [PDF]

Front Nutr, 2020
Hou G, Peng W, Wei L, Li R, Yuan Y, Huang X, Yin Y.   +6 more
europepmc   +1 more source

Microbiome-Informed Dosing: Exploring Gut Microbial Communities Impact on Mycophenolate Enterohepatic Circulation and Therapeutic Target Achievement. [PDF]

Clin Pharmacol Ther
Saqr A, Cheng S, Al-Kofahi M, Staley C, Jacobson PA.   +4 more
europepmc   +1 more source

Exploring Antibiotic-Mediated Disruption of Enterohepatic Circulation and Combined Oral Contraceptive Efficacy: A Systematic Review. [PDF]

Womens Health Rep (New Rochelle)
Elkhoury D, Reddy N, Venkatraman D, Patel P, Montalbano M.   +4 more
europepmc   +1 more source

Duodenal fluid analysis is an excellent differential diagnosis method of diseases with enterohepatic circulation disturbance. [PDF]

Medicine (Baltimore)
Dong C, Liu SX, Zou B, Shu SN, Huang ZH, Zhang BP.   +5 more
europepmc   +1 more source

Enterohepatic circulation and cholestasis

, 1987
Sulfated glycolithocholic acid, a major metabolite of the secondary bile acid lithocholic acid in newborns, is highly cholestatic when administered to experimental animals. Its taurine conjugated analogue, on the other hand, is less hepatotoxic. This thesis deals with the pathophysiology of the potentially toxic lithocholic acid sulfates and the ...
openaire   +1 more source

Nicotinamide riboside and nicotinamide mononucleotide facilitate NAD⁺ synthesis via enterohepatic circulation. [PDF]

Sci Adv
Yaku K, Palikhe S, Iqbal T, Hayat F, Watanabe Y, Fujisaka S, Izumi H, Yoshida T, Karim M, Uchida H, Nawaz A, Tobe K, Mori H, Migaud ME, Nakagawa T.   +14 more
europepmc   +1 more source