Results 11 to 20 of about 603,469 (215)

Enterohepatic Circulation and Pharmacokinetics of Genistin and Genistein in Rats [PDF]

open access: yesACS Omega, 2019
Genistin and its aglycone genistein of isoflavone are naturally occurring in plants. The aim of this study is to develop an experimental animal model of enterohepatic circulation to investigate the metabolic biotransformation of genistin and genistein in
Ya-Yu Yang, Tung-Hu Tsai
doaj   +3 more sources

Biliary excretion and enterohepatic circulation of thienorphine and its glucuronide conjugate in rats [PDF]

open access: yesActa Pharmaceutica Sinica B, 2012
Thienorphine (TNP) is a new partial opioid agonist currently developed as a promising drug candidate with the intended clinical indication for the treatment of opioid dependence.
Jingting Deng   +4 more
doaj   +2 more sources

Nuclear receptor control of enterohepatic circulation. [PDF]

open access: yesCompr Physiol, 2012
Abstract Enterohepatic circulation is responsible for the capture of bile acids and other steroids produced or metabolized in the liver and secreted to the intestine, for reabsorption back into the circulation and transport back to the liver.
Gonzalez FJ.
europepmc   +3 more sources

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

open access: yesHepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu   +20 more
wiley   +1 more source

Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis via SREBP Competitive InhibitionSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2021
Background & Aims: cAMP responsive element-binding protein 3 like 3 (CREB3L3) is a membrane-bound transcription factor involved in the maintenance of lipid metabolism in the liver and small intestine. CREB3L3 controls hepatic triglyceride and glucose
Yoshimi Nakagawa   +18 more
doaj   +1 more source

Enterohepatic Circulation of Bilirubin [PDF]

open access: yesNature, 1961
THE enterohepatic circulation of bile pigment has been the subject of protracted debate. Recirculation of bilirubin, and its bacterial reduction products, the urobilinoids, has been postulated and denied1. The availability of bilirubin labelled with carbon-14 in this Laboratory2 has obviated many of the problems previously inherent in the study of ...
R, LESTER, J D, OSTROW, R, SCHMID
openaire   +2 more sources

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Oleandrin: A Systematic Review of its Natural Sources, Structural Properties, Detection Methods, Pharmacokinetics and Toxicology

open access: yesFrontiers in Pharmacology, 2022
Oleandrin is a highly lipid-soluble cardiac glycoside isolated from the plant Nerium oleander (Apocynaceae) and is used as a traditional herbal medicine due to its excellent pharmacological properties. It is widely applied for various disease treatments,
Jinxiao Zhai   +4 more
doaj   +1 more source

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