Results 41 to 50 of about 21,092 (255)
Journal of Lipid Research, 1984 A primate model with controlled enterohepatic circulation has been developed which allowed short-term evaluation of bile salt pool size, cycling frequency, and fecal losses.
R N Redinger, J W Hawkins, D M Grace
doaj +1 more source
Enterohepatic circulation in hamsters with an extracorporeal bile duct.
Journal of Lipid Research, 1992 The present study describes a novel technique for investigations of the enterohepatic circulation in the hamster with an extracorporeal bile duct that allows long-term bile collection in the free-moving animal.
M Fuchs +4 more
doaj +1 more source
A computer study of the risk of cholesterol gallstone associated with obesity and normal weight
Scientific Reports, 2021 Obese people differ from the people of normal weight in gall bladder motility and have a higher risk of cholesterol stone formation. In this study, using a mathematical model of cholesterol homeostasis, which also considers the enterohepatic circulation ...
Krystian Kubica, Joanna Balbus
doaj +1 more source
Frontiers in Nutrition, 2022 Changes in overall bile acid (BA) levels and specific BA metabolites are involved in metabolic diseases, gastrointestinal, and liver cancer. BAs have become established as important signaling molecules that enable fine-tuned inter-tissue communication ...
Qi Zhang +20 more
doaj +1 more source
Bile analysis in heroin overdose. [PDF]
, 2007 Following its metabolism in the liver, morphine and its metabolites can be directly eliminated in bile. Then, they undergo the enterohepatic cycle (EHC) and mostly reappear in the circulation. We report a case showing the presence of morphine in bile (21.
C. CACACI +3 more
core +1 more source
Acta Pharmaceutica Sinica B, 2012 Thienorphine (TNP) is a new partial opioid agonist currently developed as a promising drug candidate with the intended clinical indication for the treatment of opioid dependence.
Jingting Deng +4 more
doaj +1 more source
Viruses, 2021 Laboratory cultivation of viruses is critical for determining requirements for viral replication, developing detection methods, identifying drug targets, and developing antivirals.
Victoria R. Tenge +8 more
doaj +1 more source
The Effects of Pregnenolone 16α-Carbonitrile Dosing on Digoxin Pharmacokinetics and Intestinal Absorption in the Rat [PDF]
, 2010 The effect of Pgp induction in rats by pregnenolone 16α-carbonitrile (PCN) (3 days, 35 mg/kg/d, p.o.) on digoxin pharmacokinetics and intestinal transport has been assessed.
Anna-Lena Ungell +12 more
core +2 more sources
Metabolic effects of intestinal absorption and enterohepatic cycling of bile acids
Acta Pharmaceutica Sinica B, 2015 The classical functions of bile acids include acting as detergents to facilitate the digestion and absorption of nutrients in the gut. In addition, bile acids also act as signaling molecules to regulate glucose homeostasis, lipid metabolism and energy ...
Courtney B. Ferrebee, Paul A. Dawson
doaj +1 more source
Involvement of UDP-Glucuronosyltransferases and Sulfotransferases in the Excretion and Tissue Distribution of Resveratrol in Mice. [PDF]
, 2017 Resveratrol is a naturally occurring polyphenolic compound with various pharmacological activities. It is unknown whether the expression of metabolizing enzymes correlates with resveratrol levels in organs and tissues.
Brenner, Stefan +8 more
core +2 more sources