Results 31 to 40 of about 603,469 (215)

Elobixibat and its potential role in chronic idiopathic constipation

open access: yesTherapeutic Advances in Gastroenterology, 2014
Chronic idiopathic constipation is highly prevalent among adults. Bile acids (BAs) and the enterohepatic BA circulation modulate colonic secretion and motility that affect transit.
Andres Acosta, Michael Camilleri
doaj   +1 more source

The regulatory role of bile acid microbiota in the progression of liver cirrhosis

open access: yesFrontiers in Pharmacology, 2023
Bile acids (BAs) are synthesized in liver tissue from cholesterol and are an important endocrine regulator and signaling molecule in the liver and intestine.
Feng Zhu   +5 more
doaj   +1 more source

The hepatobiliary axis and lipoprotein metabolism: effects of bile acid sequestrants and ileal bypass surgery

open access: yesJournal of Lipid Research, 1982
Cholesterol excretion from the body is achieved almost exclusively via the hepatobiliary axis. Disruption of the integrity of this pathway by interruption of the enterohepatic circulation produces profound changes in cholesterol metabolism that affect ...
C J Packard, J Shepherd
doaj   +1 more source

The economy of the enterohepatic circulation of bile acids in the baboon. 1. Studies of controlled enterohepatic circulation of bile acids.

open access: yesJournal of Lipid Research, 1984
A primate model with controlled enterohepatic circulation has been developed which allowed short-term evaluation of bile salt pool size, cycling frequency, and fecal losses.
R N Redinger, J W Hawkins, D M Grace
doaj   +1 more source

Enterohepatic circulation in hamsters with an extracorporeal bile duct.

open access: yesJournal of Lipid Research, 1992
The present study describes a novel technique for investigations of the enterohepatic circulation in the hamster with an extracorporeal bile duct that allows long-term bile collection in the free-moving animal.
M Fuchs   +4 more
doaj   +1 more source

The Enterohepatic Circulation

open access: yesGastroenterology, 1972
Any substance secreted in bile which is reabsorbed from the intestine and returns to the liver to appear once again in bile may be said to undergo an enterohepatic circulation (EHe). Accepting this defini­ tion, the list of endogenous and exogenous substances with an EHe is formidable.
openaire   +2 more sources

Enterohepatic circulation of triiodothyronine [PDF]

open access: yes, 1990
The major factor regulating thyroid function is thyroid stimulating hormone (TSH), a glycoprotein released by the thyrotropic cells of the pituitary gland.
Herder, W.W. (Wouter) de
core   +1 more source

Metabolic effects of intestinal absorption and enterohepatic cycling of bile acids

open access: yesActa Pharmaceutica Sinica B, 2015
The classical functions of bile acids include acting as detergents to facilitate the digestion and absorption of nutrients in the gut. In addition, bile acids also act as signaling molecules to regulate glucose homeostasis, lipid metabolism and energy ...
Courtney B. Ferrebee, Paul A. Dawson
doaj   +1 more source

A computer study of the risk of cholesterol gallstone associated with obesity and normal weight

open access: yesScientific Reports, 2021
Obese people differ from the people of normal weight in gall bladder motility and have a higher risk of cholesterol stone formation. In this study, using a mathematical model of cholesterol homeostasis, which also considers the enterohepatic circulation ...
Krystian Kubica, Joanna Balbus
doaj   +1 more source

Identification and Spatial Visualization of Dysregulated Bile Acid Metabolism in High-Fat Diet-Fed Mice by Mass Spectral Imaging

open access: yesFrontiers in Nutrition, 2022
Changes in overall bile acid (BA) levels and specific BA metabolites are involved in metabolic diseases, gastrointestinal, and liver cancer. BAs have become established as important signaling molecules that enable fine-tuned inter-tissue communication ...
Qi Zhang   +20 more
doaj   +1 more source

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