Results 31 to 40 of about 13,632 (184)

Enterohepatic Recycling

open access: yes, 2021
Broadly speaking, enterohepatic recycling (or enterohepaticcirculation) involves the circulation of metabolized and non-metabolizedcompounds (including physiologic compounds and xenobiotics) between theintestine and the liver.
Bellera, Carolina Leticia   +3 more
core   +1 more source

Recent advances in understanding and managing cholestasis [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
Cholestatic liver diseases are hereditary or acquired disorders with impaired hepatic excretion and enterohepatic circulation of bile acids and other cholephiles.
Martin Wagner, Michael Trauner
doaj   +1 more source

Bile Acids: Major Regulator of the Gut Microbiome

open access: yesMicroorganisms, 2022
Bile acids are synthesized from cholesterol and play an important role in regulating intestinal microflora. The different degrees of hydrophobicity and acidity of individual bile acids may affect their antimicrobial properties.
Chihyeok An   +14 more
doaj   +1 more source

Effects of interrupting the enterohepatic circulation in amatoxin intoxications [PDF]

open access: yes
Interruption of the enterohepatic circulation is regarded as an effective way to treat patients with amatoxin poisoning. Nonetheless, its effectiveness has not yet been systematically evaluated.
Patrick F. van Rheenen (4666621)   +6 more
core   +2 more sources

Cholesterol 7 alpha-hydroxylase: evidence for transcriptional regulation by cholesterol or metabolic products of cholesterol in the rat

open access: yesJournal of Lipid Research, 1993
Cholesterol 7 alpha-hydroxylase, the rate-determining enzyme in the bile acid biosynthesis pathway, is regulated in a negative feedback manner by hydrophobic bile salts returning to the liver via the portal circulation.
MP Jones   +5 more
doaj   +1 more source

The regulatory role of bile acid microbiota in the progression of liver cirrhosis

open access: yesFrontiers in Pharmacology, 2023
Bile acids (BAs) are synthesized in liver tissue from cholesterol and are an important endocrine regulator and signaling molecule in the liver and intestine.
Feng Zhu   +5 more
doaj   +1 more source

The hepatobiliary axis and lipoprotein metabolism: effects of bile acid sequestrants and ileal bypass surgery

open access: yesJournal of Lipid Research, 1982
Cholesterol excretion from the body is achieved almost exclusively via the hepatobiliary axis. Disruption of the integrity of this pathway by interruption of the enterohepatic circulation produces profound changes in cholesterol metabolism that affect ...
C J Packard, J Shepherd
doaj   +1 more source

The economy of the enterohepatic circulation of bile acids in the baboon. 1. Studies of controlled enterohepatic circulation of bile acids.

open access: yesJournal of Lipid Research, 1984
A primate model with controlled enterohepatic circulation has been developed which allowed short-term evaluation of bile salt pool size, cycling frequency, and fecal losses.
R N Redinger, J W Hawkins, D M Grace
doaj   +1 more source

Enterohepatic circulation in hamsters with an extracorporeal bile duct.

open access: yesJournal of Lipid Research, 1992
The present study describes a novel technique for investigations of the enterohepatic circulation in the hamster with an extracorporeal bile duct that allows long-term bile collection in the free-moving animal.
M Fuchs   +4 more
doaj   +1 more source

Identification and Spatial Visualization of Dysregulated Bile Acid Metabolism in High-Fat Diet-Fed Mice by Mass Spectral Imaging

open access: yesFrontiers in Nutrition, 2022
Changes in overall bile acid (BA) levels and specific BA metabolites are involved in metabolic diseases, gastrointestinal, and liver cancer. BAs have become established as important signaling molecules that enable fine-tuned inter-tissue communication ...
Qi Zhang   +20 more
doaj   +1 more source

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