Results 31 to 40 of about 603,469 (215)
Elobixibat and its potential role in chronic idiopathic constipation
Chronic idiopathic constipation is highly prevalent among adults. Bile acids (BAs) and the enterohepatic BA circulation modulate colonic secretion and motility that affect transit.
Andres Acosta, Michael Camilleri
doaj +1 more source
The regulatory role of bile acid microbiota in the progression of liver cirrhosis
Bile acids (BAs) are synthesized in liver tissue from cholesterol and are an important endocrine regulator and signaling molecule in the liver and intestine.
Feng Zhu +5 more
doaj +1 more source
Cholesterol excretion from the body is achieved almost exclusively via the hepatobiliary axis. Disruption of the integrity of this pathway by interruption of the enterohepatic circulation produces profound changes in cholesterol metabolism that affect ...
C J Packard, J Shepherd
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A primate model with controlled enterohepatic circulation has been developed which allowed short-term evaluation of bile salt pool size, cycling frequency, and fecal losses.
R N Redinger, J W Hawkins, D M Grace
doaj +1 more source
Enterohepatic circulation in hamsters with an extracorporeal bile duct.
The present study describes a novel technique for investigations of the enterohepatic circulation in the hamster with an extracorporeal bile duct that allows long-term bile collection in the free-moving animal.
M Fuchs +4 more
doaj +1 more source
Any substance secreted in bile which is reabsorbed from the intestine and returns to the liver to appear once again in bile may be said to undergo an enterohepatic circulation (EHe). Accepting this defini tion, the list of endogenous and exogenous substances with an EHe is formidable.
openaire +2 more sources
Enterohepatic circulation of triiodothyronine [PDF]
The major factor regulating thyroid function is thyroid stimulating hormone (TSH), a glycoprotein released by the thyrotropic cells of the pituitary gland.
Herder, W.W. (Wouter) de
core +1 more source
Metabolic effects of intestinal absorption and enterohepatic cycling of bile acids
The classical functions of bile acids include acting as detergents to facilitate the digestion and absorption of nutrients in the gut. In addition, bile acids also act as signaling molecules to regulate glucose homeostasis, lipid metabolism and energy ...
Courtney B. Ferrebee, Paul A. Dawson
doaj +1 more source
A computer study of the risk of cholesterol gallstone associated with obesity and normal weight
Obese people differ from the people of normal weight in gall bladder motility and have a higher risk of cholesterol stone formation. In this study, using a mathematical model of cholesterol homeostasis, which also considers the enterohepatic circulation ...
Krystian Kubica, Joanna Balbus
doaj +1 more source
Changes in overall bile acid (BA) levels and specific BA metabolites are involved in metabolic diseases, gastrointestinal, and liver cancer. BAs have become established as important signaling molecules that enable fine-tuned inter-tissue communication ...
Qi Zhang +20 more
doaj +1 more source

