Results 21 to 30 of about 2,029 (168)

Corrigendum: Organoid and Enteroid Modeling of Salmonella Infection [PDF]

Frontiers in Cellular and Infection Microbiology, 2018
[This corrects the article DOI: 10.3389/fcimb.2018.00102.].
Yuebang Yin, Daoguo Zhou, Daoguo Zhou
openaire   +3 more sources

Changes in transepithelial electrical resistance (TEER) of additional enteroid monolayers following infection with wildtype or CF-deficient strains.

, 2022
TEER values of differentiated ileal enteroid monolayers (46I) were recorded prior to infection and after 4 hr incubation. The change in TEER is expressed as TEER percentage change. Data presented are from four independent experiments. Each dot represents
Emily M. Smith (1326564), Eileen M. Barry (8663025), Christen L. Grassel (13155228), Antonia Papadimas (13155231), Jennifer Foulke-Abel (434893)   +4 more
core   +1 more source

Piperine as potential therapy of post-weaning porcine diarrheas: an in vitro study using a porcine duodenal enteroid model

, 2023
Post-weaning diarrhea in piglets is a major problem, resulting in a significant loss in pig production. This study aimed to investigate the effects of piperine, an alkaloid abundantly found in black peppers, on biological activities related to the ...
Saravut Satitsri, Nitwarat Ruennarong, Orawan Amnucksoradej, Chatchai Muanprasat, Nattaphong Akrimajirachoote, Kanokkan Nunta   +5 more
core   +1 more source

Effect of proinflammatory cytokines on intestinal drug transporters in human enteroid monolayers. [PDF]

Drug Metab Dispos
Thesis (Master's)--University of Washington, 2024Altered drug pharmacokinetics during inflammation or infections have been linked with elevated proinflammatory cytokines in the plasma.
Wang K, Tsang YP, Thummel KE, Kelly EJ, Mao Q, Unadkat JD.   +5 more
europepmc   +2 more sources

Human Small Intestinal Tissue Models to Assess Barrier Permeability: Comparative Analysis of Caco-2 Cells, Jejunal and Duodenal Enteroid-Derived Cells, and EpiIntestinal^TM Tissues in Membrane-Based Cultures with and Without Flow. [PDF]

Bioengineering (Basel)
Accurate in vitro models of intestinal permeability are essential for predicting oral drug absorption. Standard models like Caco-2 cells have well-known limitations, including lack of segment-specific physiology, but are widely used. Emerging models such
Moyer HL, Vergara L, Stephan C, Sakolish C, Lin HC, Chiu WA, Villenave R, Hewitt P, Ferguson SS, Rusyn I.   +9 more
europepmc   +2 more sources

Porcine colonoids and enteroids keep the memory of their origin during regeneration [PDF]

American Journal of Physiology-Cell Physiology, 2021
The development of alternative in vitro culture methods has increased in the last decade as three-dimensional organoids of various tissues, including those of the small and large intestines. Due to their multicellular composition, organoids offer advantages over traditionally used immortalized or primary cell lines. However, organoids must be accurate
Alicia M. Barnett, Jane A. Mullaney, Charlotte Hendriks, Lisa Le Borgne, Warren C. McNabb, Nicole C. Roy   +5 more
openaire   +2 more sources

Thymosin β4 dynamics during chicken enteroid development [PDF]

Molecular and Cellular Biochemistry, 2020
AbstractThe sheared avian intestinal villus-crypts exhibit high tendency to self-repair and develop enteroids in culture. Presuming that this transition process involves differential biomolecular changes, we employed matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF–MS) to find whether there were differences in the
Mohan Acharya, Rohana Liyanage, Anamika Gupta, Komala Arsi, Ann M. Donoghue, Jackson O. Lay, Narayan C. Rath   +6 more
openaire   +3 more sources

Enteroids to Study Pediatric Intestinal Drug Transport. [PDF]

Mol Pharm
Intestinal maturational changes after birth affect the pharmacokinetics (PK) of drugs, having major implications for drug safety and efficacy. However, little is known about ontogeny-related PK patterns in the intestine. To explore the accuracy of human enteroid monolayers for studying drug transport in the pediatric intestine, we compared the drug ...
Streekstra EJ, Keuper-Navis M, van den Heuvel JJMW, van den Broek P, Stommel MWJ, de Boode W, Botden S, Bervoets S, O'Gorman L, Greupink R, Russel FGM, van de Steeg E, de Wildt SN.   +12 more
europepmc   +6 more sources

Porcine intestinal enteroid (PIE) cultures can support SADS-CoV replication.

, 2022
(A) 3D PIEs were derived from small intestinal crypts and cultured in Matrigel. (B) Single cell suspensions from the 3D PIEs were seeded in Matrigel-coated 96-well plates to form 2D enteroid monolayers.
Chan Ding (317445), Yao-Wei Huang (426136), Shu Jeffrey Zhu (12867687), Yi-Xin Tang (12867684), Pan Qin (6517490), Qi-Yue Yang (12867681), Shu-Xian Chen (10719084), Jin-Yan Xie (9920614), Yong-Le Yang (10977618), Gan Wang (786657)   +9 more
core   +1 more source

Evaluating Shigella flexneri Pathogenesis in the Human Enteroid Model [PDF]

Infection and Immunity, 2019
The enteric pathogen Shigella is one of the leading causes of moderate-to-severe diarrhea and death in young children in developing countries. Transformed cell lines and animal models have been widely used to study Shigella pathogenesis.
Ranganathan, Sridevi, Doucet, Michele, Grassel, Christen L., Delaine-Elias, BreOnna, Zachos, Nicholas C., Barry, Eileen M.   +5 more
openaire   +2 more sources