Results 31 to 40 of about 2,029 (168)
Bovine Enteroids as an In Vitro Model for Infection with Bovine Coronavirus
Viruses, 2023 Bovine coronavirus (BCoV) is one of the major viral pathogens of cattle, responsible for economic losses and causing a substantial impact on animal welfare. Several in vitro 2D models have been used to investigate BCoV infection and its pathogenesis.
Ruchika Shakya +3 more
openaire +3 more sources
, 2023 The movie shows a real-time example of G. intestinalis-mNeonGreen trophozoites swimming and attaching to a PET-transwell enteroid monolayer with DMEM/F-12 as apical infection media and ENR as the basal compartment media. G. intestinalis trophozoites were
Jana Grüttner (12467874) +17 more
core +1 more source
Dasabuvir inhibits human norovirus infection in human intestinal enteroids [PDF]
mSphere, 2021 Abstract Human noroviruses (HuNoVs) are acute viral gastroenteritis pathogens that affect all age groups, yet no approved vaccines and drugs to treat HuNoV infection are available. In this study, with a human intestinal enteroid (HIE) culture system where HuNoVs are able to replicate reproducibly, we screened an antiviral compound ...
Tsuyoshi Hayashi +8 more
openaire +3 more sources
, 2022 Differentiated ileal enteroid monolayers (35I) were infected with wildtype strain CVD30 or CFA/I- and CS21-deficient strains for 8hrs (A) or infected for 4 hrs with wildtype strain CVD30 with or without pre-incubation with CFA/I- or CS21- antibodies (B).
Emily M. Smith (1326564) +4 more
core +1 more source
Evaluation of mouse enteroids as a model for Lawsonia intracellularis infection [PDF]
Veterinary Research, 2019 Lawsonia intracellularis, an obligate intracellular bacterium, is an important enteric pathogen in pig herds and horse farms worldwide. The hallmark feature of L. intracellularis infection is the proliferation of epithelial cells in intestinal crypts. A major limitation to the study of L.
Talita Pilar Resende +5 more
openaire +3 more sources
, 2022 Enterotoxigenic Escherichia coli (ETEC) is a primary causative agent of diarrhea in travelers and young children in low-to-middle-income countries (LMICs).
Emily M Smith +4 more
core +1 more source
Production of tissue-engineered intestine from expanded enteroids [PDF]
Journal of Surgical Research, 2016 Short bowel syndrome is a life-threatening condition with few solutions. Tissue-engineered intestine (TEI) is a potential treatment, but donor intestine is a limiting factor. Expanded epithelial surrogates termed enteroids may serve as a potential donor source.To produce TEI from enteroids, crypts were harvested from mice and enteroid cultures ...
Barrett P. Cromeens +5 more
openaire +2 more sources
Enteroid forming efficiency from crypts after in vitro growth with and without ISEMFs.
, 2014 Enteroid forming efficiency was measured in mono- and co-cultures with ISEMFs, with and without exogenous Rspo1 in the media (n = 3).
Garrett J. Brinkley (506133) +13 more
core +1 more source
Human enteroids: preclinical models of non-inflammatory diarrhea [PDF]
Stem Cell Research & Therapy, 2013 Researchers need an available and easy-to-use model of the human intestine to better understand human intestinal physiology and pathophysiology of diseases, and to offer an enhanced platform for developing drug therapy. Our work employs human enteroids derived from each of the major intestinal sections to advance understanding of several diarrheal ...
Kovbasnjuk, Olga +11 more
openaire +2 more sources
Infant and adult human intestinal enteroids are morphologically and functionally distinct
mBio, 2023 ABSTRACT Human intestinal enteroids (HIEs) are gaining recognition as physiologically relevant models of the intestinal epithelium. While HIEs from adults are used extensively in biomedical research, few studies have used HIEs from infants.
Grace O. Adeniyi-Ipadeola +15 more
openaire +5 more sources