Clinical breakpoint meropenem concentration modulate outer membrane vesicle production in enterotoxigenic Bacteroides fragilis. [PDF]
Arch MicrobiolAntibiotic concentrations at clinical breakpoint levels can influence bacterial physiology and virulence responses, yet their effects on outer membrane vesicle (OMV) production in anaerobic pathogens remain understudied.
Kozhakhmetova S +9 more
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Complete genome sequence of an enterotoxigenic <i>Bacteroides fragilis</i> strain 86-5443-2-2 from a piglet. [PDF]
Microbiol Resour AnnouncThis study presents the genome sequence of Bacteroides fragilis strain 86-5443-2-2, isolated from a piglet. The genome of this strain forms a single contig spanning 5.4 million base pairs with a 43.5% GC content and 4,480 genes.
Lee E, Yeom J.
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Long noncoding RNA BFAL1 mediates enterotoxigenic Bacteroides fragilis-related carcinogenesis in colorectal cancer via the RHEB/mTOR pathway. [PDF]
Cell Death Dis, 2019 Long noncoding RNAs (lncRNAs) contribute to many steps in carcinogenesis and often serve as biomarkers or therapeutic targets for tumor diagnosis and therapy.
Bao Y +11 more
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Designing a multi-epitopic vaccine against the enterotoxigenic Bacteroides fragilis based on immunoinformatics approach. [PDF]
Sci Rep, 2019 Enterotoxigenic Bacteroides fragilis is an enteric pathogen which is described as a causative agent of various intestinal infections and inflammatory diseases.
Majid M, Andleeb S.
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Dietary Salt Administration Decreases Enterotoxigenic Bacteroides fragilis (ETBF)-Promoted Tumorigenesis via Inhibition of Colonic Inflammation. [PDF]
Int J Mol Sci, 2020 Consumption of a Western-type diet has been linked to gut-microbiota-mediated colon inflammation that constitutes a risk factor for colorectal cancer. A high salt diet (HSD) exacerbates IL-17A-induced inflammation in inflammatory bowel disease and other ...
Hwang S, Yi HC, Hwang S, Jo M, Rhee KJ.
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Pharmacological Research, 2022 Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the second leading cause of cancer-related deaths in the world. The downregulation of farnesoid X receptor (FXR) is frequently founded in CRC patients.
Suhang Guo +9 more
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Analysis of Characteristics of Bovine-Derived Non-Enterotoxigenic Bacteroides fragilis and Validation of Potential Probiotic Effects. [PDF]
MicroorganismsBacteroides fragilis is a new generation of probiotics, and its probiotic effects on humans and some animals have been verified. However, research on B. fragilis in cattle is still lacking.
Wang D +9 more
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Detection of tissue colonizing bacteria and their association with clinicopathological and molecular features of inflammatory bowel disease [PDF]
Journal of Translational MedicineBackground Accumulating evidence indicates that the occurrence, development, and treatment of inflammatory bowel disease (IBD) are closely related to the intestinal microecology.
Xuanke Cao +10 more
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A review of the role of enterotoxigenic Bacteroides fragilis in the development of colorectal cancer
Basic & Clinical Cancer ResearchEnterotoxigenic Bacteroides fragilis (ETBF) plays a significant role in the development and progression of colorectal cancer (CRC) through the production of Bacteroides fragilis toxin (BFT). This toxin activates Wnt, NF-κB, and STAT3 signaling pathways,
Abolfazl Jafari-Sales +5 more
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Fecal detection of enterotoxigenic Bacteroides fragilis. [PDF]
Eur J Clin Microbiol Infect Dis, 2015 Bacteroides fragilis is a common colonic symbiote of which one subtype, enterotoxigenic Bacteroides fragilis (ETBF), causes inflammatory diarrhea. However, asymptomatic ETBF colonization is common. Through its primary virulence factor, B. fragilis toxin (BFT), ETBF causes asymptomatic, chronic colitis in C57BL/6 mice and increased colon tumorigenesis ...
Chen LA +7 more
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