Results 1 to 10 of about 1,444 (144)

Prevalence of enterotoxigenic Bacteroides fragilis in patients with colorectal cancer: a systematic review and meta-analysis [PDF]

Frontiers in Cellular and Infection Microbiology
IntroductionThe gut microbiome, specifically enterotoxigenic Bacteroides fragilis (ETBF), has been reported to play a role in colorectal cancer development.
Shijun Xia, Lijuan Ma, Hui Li, Yue Li, Linchong Yu   +4 more
doaj   +5 more sources

Quantitative profiling of colorectal cancer-associated bacteria reveals associations between fusobacterium spp., enterotoxigenic Bacteroides fragilis (ETBF) and clinicopathological features of colorectal cancer. [PDF]

PLoS ONE, 2015
Various studies have presented clinical or in vitro evidence linking bacteria to colorectal cancer, but these bacteria have not previously been concurrently quantified by qPCR in a single cohort.
Katie S Viljoen, Amirtha Dakshinamurthy, Paul Goldberg, Jonathan M Blackburn   +3 more
doaj   +6 more sources

G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis [PDF]

Communications Biology, 2021
Boleij et al. show that G protein-coupled receptor 35 (GPR35) regulates the responses to enterotoxigenic Bacteroides fragilis (ETBF) in colonic epithelial cells.
Annemarie Boleij, Payam Fathi, William Dalton, Ben Park, Xinqun Wu, David Huso, Jawara Allen, Sepideh Besharati, Robert A. Anders, Franck Housseau, Amanda E. Mackenzie, Laura Jenkins, Graeme. Milligan, Shaoguang Wu, Cynthia L. Sears   +14 more
doaj   +2 more sources

The gut microbiota of people with asthma influences lung inflammation in gnotobiotic mice [PDF]

iScience, 2023
Summary: The gut microbiota in early childhood is linked to asthma risk, but may continue to affect older patients with asthma. Here, we profile the gut microbiota of 38 children (19 asthma, median age 8) and 57 adults (17 asthma, median age 28) by 16S ...
Naomi G. Wilson, Ariel Hernandez-Leyva, Anne L. Rosen, Natalia Jaeger, Ryan T. McDonough, Jesus Santiago-Borges, Michael A. Lint, Thomas R. Rosen, Christopher P. Tomera, Leonard B. Bacharier, S. Joshua Swamidass, Andrew L. Kau   +11 more
doaj   +3 more sources

Colon Tumors in Enterotoxigenic Bacteroides fragilis (ETBF)-Colonized Mice Do Not Display a Unique Mutational Signature but Instead Possess Host-Dependent Alterations in the APC Gene [PDF]

Microbiology Spectrum, 2022
Enterotoxigenic Bacteroides fragilis (ETBF) is consistently found at higher frequency in individuals with sporadic and hereditary colorectal cancer (CRC) and induces tumorigenesis in several mouse models of CRC.
Jawara Allen, Axel Rosendahl Huber, Cayetano Pleguezuelos-Manzano, Jens Puschhof, Shaoguang Wu, Xinqun Wu, Charelle Boot, Aurelia Saftien, Heather M. O’Hagan, Hao Wang, Ruben van Boxtel, Hans Clevers, Cynthia L. Sears   +12 more
doaj   +2 more sources

Carbapenem resistance in enterotoxigenic Bacteroides fragilis isolated from colonoscopy candidates [PDF]

AMB Express
The present study aimed to determine the carbapenem resistance among Enterotoxigenic Bacteroides fragilis (ETBF) isolated from patients candidates to colonoscopy in Shiraz, Iran. A total of 201 stool samples were gathered from 201 patients. The detection
Narges Nasoohian, Ebrahim Fallahzadeh, Sahar Sabour, Saeed Soleiman-Meigooni, Taher Azimi   +4 more
doaj   +2 more sources

Biological Mechanisms of Enterotoxigenic Bacteroides fragilis Toxin: Linking Inflammation, Colorectal Cancer, and Clinical Implications [PDF]

Toxins
Enterotoxigenic Bacteroides fragilis (ETBF) has emerged as a gut microbiome pathogen that can promote intestinal inflammation and contribute to colorectal cancer (CRC).
Seyedesomaye Jasemi, Paola Molicotti, Milena Fais, Ilaria Cossu, Elena Rita Simula, Leonardo A. Sechi   +5 more
doaj   +2 more sources

The Ambivalent Nature of Bacteroides fragilis and the Interaction with Clostridioides difficile: Benefits and Disadvantages for the Human Host [PDF]

Toxins
Bacteroides fragilis is a usually beneficial colonizer of the human gut that can also act as an opportunistic pathogen, causing infection and contributing to the development and progression of important diseases.
Patrizia Spigaglia
doaj   +2 more sources

Bacteroides fragilis Toxin Induces Sequential Proteolysis of E-Cadherin and Inflammatory Response in Mouse Intestinal Epithelial Cell Line [PDF]

Microorganisms
Enterotoxigenic Bacteroides fragilis (ETBF) is an intestinal bacterium that secretes the metalloprotease Bacteroides fragilis toxin (BFT), which induces E-cadherin cleavage and interleukin-8 secretion in human intestinal epithelial cell lines.
Woo-Seung Kim, Soonjae Hwang, Sun-Yeong Gwon, Minjeong Jo, Sang-Hyeon Yoo, Jiyun Hong, Ha-Neul Jang, Ju-Eun Hong, Da-Hye Kang, Miyong Yun, Ki-Jong Rhee   +10 more
doaj   +2 more sources

The gut microbiome in colorectal cancer: mechanisms of carcinogenesis and emerging microbiota-targeted therapies [PDF]

Discover Oncology
Colorectal cancer (CRC) remains a leading cause of cancer-related mortality globally. Beyond established genetic and environmental risk factors, the gut microbiome is now recognized as a pivotal contributor to CRC pathogenesis, progression, and ...
Yue Li, Xingyu Shen, Deqiang Wang, Kang Sun   +3 more
doaj   +2 more sources