Results 1 to 10 of about 64,016 (171)

Human Enterovirus B: Selective Inhibition by Quinoxaline Derivatives and Bioinformatic RNA-Motif Identification as New Targets [PDF]

Pharmaceuticals, 2022
The Enterovirus genus includes many viruses that are pathogenic in humans, including Coxsackie viruses and rhinoviruses, as well as the emerging enteroviruses D68 and A71.
Silvia Madeddu, Roberta Ibba, Giuseppina Sanna, Sandra Piras, Federico Riu, Alessandra Marongiu, Annalisa Ambrosino, Paola Caria, Valentina Onnis, Gianluigi Franci, Aldo Manzin, Antonio Carta   +11 more
doaj   +4 more sources

Transmission of human enterovirus 85 recombinants containing new unknown serotype HEV-B donor sequences in Xinjiang Uighur autonomous region, China. [PDF]

PLoS ONE, 2013
BACKGROUND: Human enterovirus 85 (HEV85), whose prototype strain (Strain BAN00-10353/BAN/2000) was isolated in Bangladesh in 2000, is a recently identified serotype within the human enterovirus B (HEV-B) species.
Qiang Sun, Yong Zhang, Shuangli Zhu, Huifang Tian, Guohong Huang, Hui Cui, Xiaolei Li, Dongmei Yan, Zhen Zhu, Jing Li, Peng Zheng, Huafang Jiang, Bo Zhang, Xiaojuan Tan, Hui Zhu, Hongqiu An, Wenbo Xu   +16 more
doaj   +4 more sources

Human B cells and dendritic cells are susceptible and permissive to enterovirus D68 infection

mSphere
Enterovirus D68 (EV-D68) is predominantly associated with mild respiratory infections, but can also cause severe respiratory disease and extra-respiratory complications, including acute flaccid myelitis.
Brigitta M. Laksono, Syriam Sooksawasdi Na Ayudhya, Muriel Aguilar-Bretones, Carmen W. E. Embregts, Gijsbert P. van Nierop, Debby van Riel   +5 more
doaj   +3 more sources

Human Enterovirus Group B Viruses Rely on Vimentin Dynamics for Efficient Processing of Viral Nonstructural Proteins [PDF]

Journal of Virology, 2020
A virus needs the host cell in order to replicate and produce new progeny viruses. For this, the virus takes over the host cell and modifies it to become a factory for viral proteins. Irrespective of the specific virus family, these proteins can be divided into structural and nonstructural proteins.
Turkki, Paula, Laajala, Mira, Flodström-Tullberg, Malin, Marjomäki, Varpu   +3 more
openaire   +5 more sources

Enterovirus species B isolates recovered from children with acute flaccid paralysis in Nigeria, 2010 and 2012

Journal of Clinical Virology Plus, 2022
In 2010 and 2012, between June and October (the peak period of enterovirus circulation in Nigeria), 59 archived enterovirus isolates (recovered as part of the Acute Flaccid Paralysis surveillance program) were randomly selected and typed in this study ...
T.O.C. Faleye, M.O. Adewumi, M.O. Japhet, U.E. George, O.M. David, A.O. Oluyege, J.A. Adeniji, O. Famurewa   +7 more
doaj   +1 more source

Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18

mBio, 2022
Virus-receptor interactions determine viral host range and tissue tropism. CD55 and human neonatal Fc receptor (FcRn) were found to be the binding and uncoating receptors for some of the echovirus-related enterovirus species B serotypes in our previous ...
Xiangpeng Chen, Xiao Qu, Congcong Liu, Yong Zhang, Guigen Zhang, Pu Han, Yali Duan, Qi Li, Liang Wang, Wenjing Ruan, Peiyi Wang, Wensheng Wei, George F. Gao, Xin Zhao, Zhengde Xie   +14 more
doaj   +1 more source

Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B [PDF]

Cell, 2019
Enterovirus B (EV-B), a major proportion of the genus Enterovirus in the family Picornaviridae, is the causative agent of severe human infectious diseases. Although cellular receptors for coxsackievirus B in EV-B have been identified, receptors mediating virus entry, especially the uncoating process of echovirus and other EV-B remain obscure.
Zhao, Xin, Zhang, Guigen, Liu, Sheng, Chen, Xiangpeng, Peng, Ruchao, Dai, Lianpan, Qu, Xiao, Li, Shihua, Song, Hao, Gao, Zhengrong, Yuan, Pengfei, Liu, Zhiheng, Li, Changyao, Shang, Zifang, Li, Yan, Zhang, Meifan, Qi, Jianxun, Wang, Han, Du, Ning, Wu, Yan, Bi, Yuhai, Gao, Shan, Shi, Yi, Yan, Jinghua, Zhang, Yong, Xie, Zhengde, Wei, Wensheng, Gao, George F.   +27 more
openaire   +2 more sources

Multicenter Evaluation of the QIAstat-Dx Respiratory Panel for the Detection of Viruses and Bacteria in Nasopharyngeal Swab Specimens [PDF]

, 2020
The QIAstat-Dx Respiratory Panel (QIAstat-Dx RP) is a multiplex in vitro diagnostic test for the qualitative detection of 20 pathogens directly from nasopharyngeal swab (NPS) specimens. The assay is performed using a simple sample-to-answer platform with
Granato, Paul, Hannet, Irene, Hansen, Glen, Leber, Amy L., Lisby, Jan Gorm, Pareja, Josep, Relich, Ryan F., Schneider, Uffe Vest, Young, Stephen   +8 more
core   +1 more source

Biological Significance of a Human Enterovirus B-Specific RNA Element in the 3′ Nontranslated Region [PDF]

Journal of Virology, 2002
ABSTRACT The secondary structures predicted for the enteroviral 3′ nontranslated region (3′NTR) all seem to indicate a conformation consisting of two (X and Y) hairpin structures. The higher-order RNA structure of the 3′NTR appears to exist as an intramolecular kissing interaction between the loops of these two hairpin structures.
Merkle, I., Ooij, M.J.M. van, Kuppeveld, F.J.M. van, Glaudemans, D.H., Galama, J.M.D., Henke, A., Zell, R., Melchers, W.J.G.   +7 more
openaire   +4 more sources

The Structure, Function, and Mechanisms of Action of Enterovirus Non-structural Protein 2C

Frontiers in Microbiology, 2020
Enteroviruses are a group of RNA viruses belonging to the family Picornaviridae. They include human enterovirus groups A, B, C, and D as well as non-human enteroviruses.
Shao-Hua Wang, Kuan Wang, Ke Zhao, Shu-Cheng Hua, Juan Du, Juan Du   +5 more
doaj   +1 more source