Results 1 to 10 of about 1,203,932 (249)

Human Enterovirus B: Selective Inhibition by Quinoxaline Derivatives and Bioinformatic RNA-Motif Identification as New Targets [PDF]

Pharmaceuticals, 2022
The Enterovirus genus includes many viruses that are pathogenic in humans, including Coxsackie viruses and rhinoviruses, as well as the emerging enteroviruses D68 and A71.
Silvia Madeddu, Roberta Ibba, Giuseppina Sanna, Sandra Piras, Federico Riu, Alessandra Marongiu, Annalisa Ambrosino, Paola Caria, Valentina Onnis, Gianluigi Franci, Aldo Manzin, Antonio Carta   +11 more
doaj   +8 more sources

Transmission of human enterovirus 85 recombinants containing new unknown serotype HEV-B donor sequences in Xinjiang Uighur autonomous region, China. [PDF]

PLoS ONE, 2013
BACKGROUND: Human enterovirus 85 (HEV85), whose prototype strain (Strain BAN00-10353/BAN/2000) was isolated in Bangladesh in 2000, is a recently identified serotype within the human enterovirus B (HEV-B) species.
Qiang Sun, Yong Zhang, Shuangli Zhu, Huifang Tian, Guohong Huang, Hui Cui, Xiaolei Li, Dongmei Yan, Zhen Zhu, Jing Li, Peng Zheng, Huafang Jiang, Bo Zhang, Xiaojuan Tan, Hui Zhu, Hongqiu An, Wenbo Xu   +16 more
doaj   +5 more sources

Human B cells and dendritic cells are susceptible and permissive to enterovirus D68 infection

mSphere
Enterovirus D68 (EV-D68) is predominantly associated with mild respiratory infections, but can also cause severe respiratory disease and extra-respiratory complications, including acute flaccid myelitis.
Brigitta M. Laksono, Syriam Sooksawasdi Na Ayudhya, Muriel Aguilar-Bretones, Carmen W. E. Embregts, Gijsbert P. van Nierop, Debby van Riel   +5 more
doaj   +4 more sources

Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B [PDF]

Cell, 2019
Enterovirus B (EV-B), a major proportion of the genus Enterovirus in the family Picornaviridae, is the causative agent of severe human infectious diseases. Although cellular receptors for coxsackievirus B in EV-B have been identified, receptors mediating virus entry, especially the uncoating process of echovirus and other EV-B remain obscure.
Xiao Qu, Shan Gao, Jianxun Qi, Xiangpeng Chen, Han Wang, Yan Wu, George F. Gao, Meifan Zhang, Hao Song, Sheng Liu, Jinghua Yan, Yi Shi, Yan Li, Xin Zhao, Ning Du, Yong Zhang, Zhengde Xie, Guigen Zhang, Pengfei Yuan, Yuhai Bi, Zifang Shang, Wensheng Wei, Ruchao Peng, Shihua Li, Zhengrong Gao, Lianpan Dai, Changyao Li, Zhiheng Liu   +27 more
openaire   +4 more sources

Sentinel surveillance for human enterovirus 71 in Sarawak, Malaysia: lessons from the first 7 years [PDF]

BMC Public Health, 2006
Background A major outbreak of human enterovirus 71-associated hand, foot and mouth disease in Sarawak in 1997 marked the beginning of a series of outbreaks in the Asia Pacific region.
Yao Sik-King, Yao Sik-Chi, Wee Thian-Yew, Teo Bibiana, Perera David, Yusof Mohd, Yee Siew-Fung, Leong Yee-Wei, Ong Flora, Gias Edna LM, Podin Yuwana, Kiyu Andrew, Arif Mohd, Cardosa Mary   +13 more
doaj   +6 more sources

Development of a reverse transcription-loop-mediated isothermal amplification (RT-LAMP) system for a highly sensitive detection of enterovirus in the stool samples of acute flaccid paralysis cases [PDF]

BMC Infectious Diseases, 2009
Background In the global eradication program for poliomyelitis, the laboratory diagnosis plays a critical role by isolating poliovirus (PV) from the stool samples of acute flaccid paralysis (AFP) cases. In this study, we developed a reverse transcription-
Wakita Takaji, Yoshida Hiromu, Nishimura Yorihiro, Yan Dongmei, Ling Hua, Arita Minetaro, Shimizu Hiroyuki   +6 more
doaj   +4 more sources

Comprehensive Enteroviral Serology Links Infection and Anti‐Melanoma Differentiation‐Associated Protein 5 Dermatomyositis [PDF]

ACR Open Rheumatology
Objective Idiopathic inflammatory myopathies (IIMs) are a group of heterogeneous, systemic autoimmune diseases characterized by specific clinical features and, frequently, skeletal muscle inflammation.
Sahana Jayaraman, Eleni Tiniakou, William R. Morgenlander, Miso Na, Lisa Christopher‐Stine, H. Benjamin Larman   +5 more
doaj   +2 more sources

Human Enterovirus Group B Viruses Rely on Vimentin Dynamics for Efficient Processing of Viral Nonstructural Proteins [PDF]

Journal of Virology, 2020
A virus needs the host cell in order to replicate and produce new progeny viruses. For this, the virus takes over the host cell and modifies it to become a factory for viral proteins. Irrespective of the specific virus family, these proteins can be divided into structural and nonstructural proteins.
Turkki, Paula, Laajala, Mira, Flodström-Tullberg, Malin, Marjomäki, Varpu   +3 more
openaire   +6 more sources

Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18

mBio, 2022
Virus-receptor interactions determine viral host range and tissue tropism. CD55 and human neonatal Fc receptor (FcRn) were found to be the binding and uncoating receptors for some of the echovirus-related enterovirus species B serotypes in our previous ...
Xiangpeng Chen, Xiao Qu, Congcong Liu, Yong Zhang, Guigen Zhang, Pu Han, Yali Duan, Qi Li, Liang Wang, Wenjing Ruan, Peiyi Wang, Wensheng Wei, George F. Gao, Xin Zhao, Zhengde Xie   +14 more
doaj   +1 more source

Multicenter Evaluation of the QIAstat-Dx Respiratory Panel for the Detection of Viruses and Bacteria in Nasopharyngeal Swab Specimens [PDF]

, 2020
The QIAstat-Dx Respiratory Panel (QIAstat-Dx RP) is a multiplex in vitro diagnostic test for the qualitative detection of 20 pathogens directly from nasopharyngeal swab (NPS) specimens. The assay is performed using a simple sample-to-answer platform with
Granato, Paul, Hannet, Irene, Hansen, Glen, Leber, Amy L., Lisby, Jan Gorm, Pareja, Josep, Relich, Ryan F., Schneider, Uffe Vest, Young, Stephen   +8 more
core   +1 more source