Results 11 to 20 of about 64,082 (215)

Human B cells and dendritic cells are susceptible and permissive to enterovirus D68 infection

mSphere
Enterovirus D68 (EV-D68) is predominantly associated with mild respiratory infections, but can also cause severe respiratory disease and extra-respiratory complications, including acute flaccid myelitis.
Brigitta M. Laksono, Syriam Sooksawasdi Na Ayudhya, Muriel Aguilar-Bretones, Carmen W. E. Embregts, Gijsbert P. van Nierop, Debby van Riel   +5 more
doaj   +3 more sources

Human Enterovirus Group B Viruses Rely on Vimentin Dynamics for Efficient Processing of Viral Nonstructural Proteins [PDF]

Journal of Virology, 2020
A virus needs the host cell in order to replicate and produce new progeny viruses. For this, the virus takes over the host cell and modifies it to become a factory for viral proteins. Irrespective of the specific virus family, these proteins can be divided into structural and nonstructural proteins.
Turkki, Paula, Laajala, Mira, Flodström-Tullberg, Malin, Marjomäki, Varpu   +3 more
openaire   +5 more sources

Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B [PDF]

Cell, 2019
Enterovirus B (EV-B), a major proportion of the genus Enterovirus in the family Picornaviridae, is the causative agent of severe human infectious diseases. Although cellular receptors for coxsackievirus B in EV-B have been identified, receptors mediating virus entry, especially the uncoating process of echovirus and other EV-B remain obscure.
Zhao, Xin, Zhang, Guigen, Liu, Sheng, Chen, Xiangpeng, Peng, Ruchao, Dai, Lianpan, Qu, Xiao, Li, Shihua, Song, Hao, Gao, Zhengrong, Yuan, Pengfei, Liu, Zhiheng, Li, Changyao, Shang, Zifang, Li, Yan, Zhang, Meifan, Qi, Jianxun, Wang, Han, Du, Ning, Wu, Yan, Bi, Yuhai, Gao, Shan, Shi, Yi, Yan, Jinghua, Zhang, Yong, Xie, Zhengde, Wei, Wensheng, Gao, George F.   +27 more
openaire   +2 more sources

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

Liver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala, Bridget Whitehead, Justin Godown, Matt Hall, Anna Banc‐Husu, Estella M. Alonso, Sarah A. Taylor   +6 more
wiley   +1 more source

Biological Significance of a Human Enterovirus B-Specific RNA Element in the 3′ Nontranslated Region [PDF]

Journal of Virology, 2002
ABSTRACT The secondary structures predicted for the enteroviral 3′ nontranslated region (3′NTR) all seem to indicate a conformation consisting of two (X and Y) hairpin structures. The higher-order RNA structure of the 3′NTR appears to exist as an intramolecular kissing interaction between the loops of these two hairpin structures.
Merkle, I., Ooij, M.J.M. van, Kuppeveld, F.J.M. van, Glaudemans, D.H., Galama, J.M.D., Henke, A., Zell, R., Melchers, W.J.G.   +7 more
openaire   +4 more sources

Natural Recombination Event within the Capsid Genomic Region Leading to a Chimeric Strain of Human Enterovirus B [PDF]

Journal of Virology, 2007
ABSTRACT Recombination between two strains is a known phenomenon for enteroviruses replicating within a single cell. We describe a recombinant strain recovered from human stools, typed as coxsackievirus B4 (CV-B4) and CV-B3 after partial sequencing of the VP1 and VP2 coding regions, respectively.
Bouslama, Lamjed, Nasri, Dorsaf, Chollet, Lionel, Belguith, Khaoula, Bourlet, Thomas, Aouni, Mahjoub, Pozzetto, Bruno, Pillet, Sylvie   +7 more
openaire   +4 more sources

Human Enterovirus Species B in Ileocecal Crohn's Disease

Clinical and Translational Gastroenterology, 2013
Advanced ileocecal Crohn's disease (ICD) is characterized by strictures, inflammation in the enteric nervous system (myenteric plexitis), and a high frequency of NOD2 mutations. Recent findings implicate a role of NOD2 and another CD susceptibility gene, ATG16L1, in the host response against single-stranded RNA (ssRNA) viruses.
Nyström, Niklas, Berg, Tove, Lundin, Elin, Skog, Oskar, Hansson, Inga, Frisk, Gun, Juko-Pecirep, Ivana, Nilsson, Mats, Gyllensten, Ulf, Finkel, Yigael, Fuxe, Jonas, Wanders, Alkwin   +11 more
openaire   +3 more sources

Changing epidemiology of influenza and other respiratory viruses in the first year of COVID-19 pandemic

Journal of Infection and Public Health, 2021
Introduction: We aimed to determine the epidemiological change in influenza and other respiratory tract viruses isolated from patients with nasopharyngeal swab samples in our hospital during the COVID-19 period.
Harun Agca, Halis Akalin, Imran Saglik, Mustafa Hacimustafaoglu, Solmaz Celebi, Beyza Ener   +5 more
doaj   +1 more source

Production of Cross‐Reactive Peptide Antibodies against Viral Capsid Proteins of Human Enterovirus B to Apply Diagnostic Reagent [PDF]

Microbiology and Immunology, 2007
AbstractThe coxsackievirus group B (CVB) of the genus Enterovirus and the species human enterovirus B is a nonenveloped virus containing a single‐stranded positive‐sense RNA genome. Coxsackievirus has icosahedral symmetry and four capsid proteins, VP1, VP2, VP3, and VP4.
Soo-Young, Jeong, Jeonghyun, Ahn, Young-Joo, Cho, Yeun-Jung, Kim, Dae-Sun, Kim, Youngmee, Jee, Heuiran, Lee, Jae-Hwan, Nam   +7 more
openaire   +2 more sources

Myocarditis, disseminated infection, and early viral persistence following experimental coxsackievirus B infection of cynomolgus monkeys. [PDF]

, 2013
Coxsackievirus B (CVB) infection is a common cause of acute viral myocarditis. The clinical presentation of myocarditis caused by this enterovirus is highly variable, ranging from mildly symptoms to complete hemodynamic collapse.
Blanchard, James, Bohm, Rudolf, Cammock, Cheryl E, Halnon, Nancy J, Krogstad, Paul A, Lai, Chi, Miller, Christopher J, Skoczylas, Jill   +7 more
core   +2 more sources