Results 61 to 70 of about 20,149 (219)

Epigenetic analyses suggest different pathways during pregnancy for development of Type 1 diabetes in children with high versus low‐neutral human leukocyte antigen‐risk

Journal of Internal Medicine, EarlyView.
Abstract Background and objective The development of Type 1 diabetes (T1D) is shaped by genetic predisposition and epigenetic regulation. Human leukocyte antigen (HLA) risk alleles are major genetic determinants, but the epigenetic landscape in relation to disease onset remains unclear.
Shamila D. Alipoor, Angelica Ahrens, Julia Åkesson, Thomas Hillerton, Mika Gustafsson, Maria Lerm, Johnny Ludvigsson   +6 more
wiley   +1 more source

Impact of the BioFire FilmArray Meningitis‐Encephalitis Panel on Management of Suspected Paediatric Central Nervous System Infections: A Single‐Centre Retrospective Cohort Study

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background Meningoencephalitis causes significant morbidity and mortality in children worldwide. Prompt diagnosis remains challenging, yet advances in molecular diagnostic technology have improved diagnostic performance. This study examined whether the introduction of the BioFire FilmArray meningitis/encephalitis (ME) multiplex panel impacted ...
Louisa Mary Churcher, Adam William Bartlett, Stella Pendle, Rob Slade, Phoebe C. M. Williams   +4 more
wiley   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Completely conserved VP2 residue K140 of KREMEN1-dependent enteroviruses is critical for virus-receptor interactions and viral infection

mBio
The KREMEN1 (KRM1) protein is a cellular receptor for multiple enteroviruses that cause hand, foot, and mouth disease (HFMD), including coxsackievirus CVA2, CVA3, CVA4, CVA5, CVA6, CVA10, and CVA12.
Zeyu Liu, Xue Li, Xiaohong Li, Xingyu Yan, Yuan Tian, Yue Zhao, Kexin Liu, Pei Hao, Shuye Zhang, Chao Zhang   +9 more
doaj   +1 more source

Successful Treatment of Severe Purpura Fulminans With Anakinra

Pediatric Dermatology, EarlyView.
ABSTRACT Purpura fulminans (PF) is a rare, often fatal pediatric condition characterized by intravascular thrombosis and hemorrhagic infarction of the skin. A timely diagnosis and treatment are paramount to prevent the involvement of internal organs, causing disseminated intravascular coagulation and gangrene of the extremities.
Francesco Zulian, Luca Spiezia, Antonio Amabile, Francesca Tirelli, Alessandra Meneghel   +4 more
wiley   +1 more source

Emergence of Fluoxetine-Resistant Variants during Treatment of Human Pancreatic Cell Cultures Persistently Infected with Coxsackievirus B4

Viruses, 2019
This study reports the antiviral activity of the drug fluoxetine against some enteroviruses (EV). We had previously established a model of persistent coxsackievirus B4 (CVB4) infection in pancreatic cell cultures and demonstrated that fluoxetine could ...
Enagnon Kazali Alidjinou, Antoine Bertin, Famara Sane, Delphine Caloone, Ilka Engelmann, Didier Hober   +5 more
doaj   +1 more source

Just be the parent

Journal of Hospital Medicine, EarlyView.
Andrew S. Kern‐Goldberger
wiley   +1 more source

Antibody Serologies and Diagnostic Considerations in Reactive Infectious Mucocutaneous Eruption

Pediatric Dermatology, EarlyView.
ABSTRACT Reactive infectious mucocutaneous eruption (RIME) is an uncommon, post‐infectious mucocutaneous condition often associated with Mycoplasma pneumoniae, but which can be triggered by other pathogens. We retrospectively reviewed eight young adult patients diagnosed with RIME over a 10‐year period, all of whom had positive Mycoplasma pneumoniae ...
Aaron D. Smith, Olivia Cohen, Peter Jowdy, Catherine E. Lyons, Lauren Yi, Barrett Zlotoff   +5 more
wiley   +1 more source

A Mini Review of the Zoonotic Threat Potential of Influenza Viruses, Coronaviruses, Adenoviruses, and Enteroviruses

Frontiers in Public Health, 2018
During the last two decades, scientists have grown increasingly aware that viruses are emerging from the human–animal interface. In particular, respiratory infections are problematic; in early 2003, World Health Organization issued a worldwide alert for ...
Emily S. Bailey, Emily S. Bailey, Jane K. Fieldhouse, Jane K. Fieldhouse, Jessica Y. Choi, Jessica Y. Choi, Gregory C. Gray, Gregory C. Gray, Gregory C. Gray, Gregory C. Gray   +9 more
doaj   +1 more source

Enteroviruses and Parechoviruses [PDF]

Microbiology Spectrum, 2016
ABSTRACT Infections with enteroviruses and human parechoviruses are highly prevalent, particularly in neonates, where they may cause substantial morbidity and mortality. Individuals with B-cell-related immunodeficiencies are at risk for severe enteroviral infections, usually a chronic and fatal meningoencephalitis.
openaire   +2 more sources