Results 111 to 120 of about 1,014,373 (292)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Early Life Health and Adult Earnings: Evidence from a Large Sample of Siblings and Twins [PDF]

open access: yes
We study the relationship between early life health and adult earnings using a unique dataset that covers almost the entire population of Swedish males born between 1950 and 1970.
Lundborg, Petter   +2 more
core  

New genera and species of Lygaeoidea (Heteroptera: Lygaeoidea: Rhyparochromidae) [PDF]

open access: yes, 1998
Afralampes capensis is described as a new genus and species in the Megalonotini. The systematic position of Serranegra Lindberg is discussed, a new species is described from South Africa and a key to species included.
Slater, James A.
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A revision of the striatella species group of the genus Rhagoletis (Diptera: Tephritidae) [PDF]

open access: yes, 1999
A taxonomic revision of species of the striatella group, including descriptions ofthree new species from Mexico, Nicaragua and Costa Rica is presented. To date we recognize 6 species in this group: Rhagoletis striatella, R. jamaicensis, R. macquartii, R.
Frias L., Daniel   +1 more
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Estimating body weight from foot measurements in the Eastern Turkish Population using linear methods and artificial neural networks

open access: yesMedicine Science
In forensic and archaeological contexts, accurately determining an individual's age, sex, height, and weight is essential for the identification of unidentified bodies and dismembered remains.
Omer Turan   +4 more
doaj   +1 more source

Model of mobile agents for sexual interactions networks

open access: yes, 2005
We present a novel model to simulate real social networks of complex interactions, based in a granular system of colliding particles (agents). The network is build by keeping track of the collisions and evolves in time with correlations which emerge due ...
Gonzalez, M. C.   +2 more
core   +2 more sources

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