Results 131 to 140 of about 1,014,373 (292)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Public-Private Wage Gap in Australia: Variation Along the Distribution [PDF]

Previous research on public-private wage differentials in Australia is scarce and has focused on the central parts of the conditional wage distribution.
Amy Y.C. Liu, Lixin Cai
core  

Reaching for the Cap and Gown: Progress Toward Success Boston's College Completion Goals for Graduates of the Boston Public Schools [PDF]

, 2016
A new report, prepared for Mayor Martin J. Walsh and the Success Boston college completion initiative, shows a remarkable increase in both the percentage and the number of Boston Public Schools graduates who complete college within six years.
Anika Eaton, Barbara Hindley, Beth Gamse, Hayley Didriksen, Jane Furey, Joseph McLaughlin, Neil Sullivan, Tamara Linkow   +7 more
core  

Puberty development of entire males and risk of boar taint

, 2020
La castration des porcelets mâles a pour but de diminuer les risques de comportement agressif et d’éviter des défauts de qualité de viande. En effet, chez certains mâles entiers, l’androsténone (molécule produite dans les testicules) et le scatol (produit par les bactéries du tube digestif) s’accumulent dans le gras et donnent une odeur désagréable à ...
Dugue, Claire, Ferchaud, Stéphane, Grivault, Doryan, Mercat, Marie J., Boulot, Sylviane, Prunier, Armelle, Larzul, Catherine   +6 more
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

A HAIR-PIN EXTRACTED ENTIRE FROM THE MALE BLADDER BY MEANS OF THE LITHOTRITE. [PDF]

The Lancet
n ...
openaire   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Memoirs of the Queensland Museum. [PDF]

, 1988
v.35:pt.2 ...
Hamlyn-Harris, Ronald, Hamlyn-Harris, Ronald, 1874-, Queensland Museum., Queensland Museum.   +3 more
core   +5 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Effects of socialising piglets on sow and piglet performance and behaviour of entire male piglets

Animal
Entire male pigs show more aggressive behaviour and mounting than female pigs. By sorting growing pigs into male and female pens, at least half of the pigs are protected from the aggressive behaviour and mounting of the entire males.
L. Rydhmer, K. Andersson
doaj   +1 more source