Results 141 to 150 of about 1,014,373 (292)

How mortality patterns have changed in Portugal [PDF]

open access: yes, 2017
Changes in social structures, advances in medicine and technology highly contributed to life expectancy increase across the entire world. Thus, longevity’s increase occurs as a result of significant improvements in health and consequent reductions in ...
Ribeiro, Filipe
core  

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Epitoky in Scutisotoma stepposa (Collembola; Isotomidae)

open access: yesSoil Organisms, 2011
Reproductive males of Scutisotoma stepposa Martynova from two basins of Vitim Plateau (Russia: East Siberia) display epitoky in three forms. ‘Supermales’ are armed with strong macrosetae, brushes on ventrum of abdomen, callosities on tube and legs, bent
Ayuna Chimitova, Mikhail Potapov
doaj  

Size composition, monthly condition factor and morphometrics for fishery-dependent samples of Rioraja agassizi (Chondrichthyes: Rajidae), off Santos, Southeast Brazil

open access: yesNeotropical Ichthyology
Specimens of Rioraja agassizi were collected monthly off Santos, Southeast Brazil, between latitudes 23º37'S and 27º40'S, from March, 2005 to March, 2006. A total number of 278 males and 1023 females were captured.
M. Cristina Oddone   +3 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Women, Children, and Industrialization in the Early Republic: Evidence from the Manufacturing Censuses [PDF]

open access: yes
The first half of the nineteenth century was a critical juncture regarding the emergence of female participation in the market economy, the increase in the wage of females relative to that of adult males, and the evolution of large scale firms in both ...
Claudia Goldin, Kenneth L. Sokoloff
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

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