Results 81 to 90 of about 1,391 (151)
CNS Neuroscience &Therapeutics, Volume 31, Issue 5, May 2025.ABSTRACT Background Vascular dementia, the second most common type of dementia globally after Alzheimer's disease, is associated with neuroinflammation. Activation of the NLRP3 inflammasome, an important pattern recognition receptor in human innate immunity, plays a key role in the pathogenesis of vascular dementia.
Yujia Lu +10 more
wiley +1 more source
Brain Science Advances, 2016 Objective Real-time monitoring of cytokine secretion at the single immunocyte level, based on the concept of immune cells, sociology has been recently reported.
Mingxia Zhang +12 more
doaj +1 more source
Can cannibalizing cancer cells challenge classic cell death classification?
Biomedical Journal, 2017 In this issue of the Biomedical Journal, we learn about a novel are still largely mysterious mechanism of cell death that is challenging classification systems of cell death pathways and could have important implications for future cancer therapy.
Emma Louise Walton
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P53 clears aneuploid cells by entosis [PDF]
Cell Death & Differentiation, 2020 Dario, Rizzotto, Andreas, Villunger
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TRAIL signalling promotes entosis in colorectal cancer
, 2020 Datasets and source-code underlying the computational analyses investigating the clinical association among TRAIL signalling, cell-in-cell structures, and colorectal cancer included in the manuscript "TRAIL signalling promotes entosis in colorectal ...
Cavanagh, Brenton L. +7 more
core +1 more source
Dying from within: granzyme B converts entosis to emperitosis [PDF]
Cell Death & Differentiation, 2013 The term granzyme was coined by the late Jorg Tschopp – in one of the most beautiful papers ever published – and Tschopp and Daniele Masson defined the characteristics and members of the family.1 The family members, cytotoxic T cell (CTL)-specific proteases, neatly fitted existing paradigms of protease specificity, although the functions were (and ...
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Orai1-mediated store-operated Ca2+ entry (SOCE) in breast cancer signaling and entosis
, 2023 The intracellular Ca2+ concentrations are highly regulated by a variety of Ca2+ channels that can be disrupted in cancer. Store-operated Ca2+ entry (SOCE) is a primary source of Ca2+ influx in non-excitable cells, which is activated by the decrease in ...
Park, Chan Young
core
Regulated cell death in glioma: promising targets for natural small-molecule compounds
Frontiers in OncologyGliomas are prevalent malignant tumors in adults, which can be categorized as either localized or diffuse gliomas. Glioblastoma is the most aggressive and deadliest form of glioma.
Mingyu Han +6 more
doaj +1 more source
Gene Expression Regulation and the Signal Transduction of Programmed Cell Death
Current Issues in Molecular BiologyCell death is of great significance in maintaining tissue homeostasis and bodily functions. With considerable research coming to the fore, it has been found that programmed cell death presents in multiple modalities in the body, which is not only limited
Saqirile +5 more
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