Results 161 to 170 of about 651,887 (304)

Data-driven enzyme engineering to identify function-enhancing enzymes. [PDF]

Protein Eng Des Sel, 2023
Jiang Y, Ran X, Yang ZJ.
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Synzymes: The Future of Modern Enzyme Engineering. [PDF]

Appl Biochem Biotechnol
Palabiyik AA.
europepmc   +1 more source

Protein modelling for enzyme engineering [PDF]

, 2017
Guallar, Victor, Santiago, Gerard
core  

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Confocal Absorbance-Activated Droplet Sorting (cAADS) for Enzyme Engineering. [PDF]

Adv Sci (Weinh)
Kaba AM, Gounel S, Beneyton T, Buisson L, Baret JC, Mano N.   +5 more
europepmc   +1 more source

Nature-inspired Enzyme engineering and sustainable catalysis: biochemical clues from the world of plants and extremophiles. [PDF]

Front Bioeng Biotechnol, 2023
Chatterjee A, Puri S, Sharma PK, Deepa PR, Chowdhury S.   +4 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Organelle-Targeted Multi-Enzyme Engineering Enables Medium-Chain Fatty Acid Production in <i>Chlamydomonas reinhardtii</i>. [PDF]

J Microbiol Biotechnol
Roh Y, Shin S, Han CH, Eom JI, Park S, Son M, Pan CH, Shin CH, Yamaoka Y.   +8 more
europepmc   +1 more source

Directed Evolution Methods for Enzyme Engineering. [PDF]

Molecules, 2021
Nirantar SR.
europepmc   +1 more source