Results 31 to 40 of about 308,992 (299)

Fluorimetric microplate assay for the determination of extracellular alkaline phosphatase kinetics and inhibition kinetics in activated sludge

open access: yesMethodsX, 2023
The microbial enzyme alkaline phosphatase contributes to the removal of organic phosphorus compounds from wastewaters. To cope with regulatory threshold values for permitted maximum phosphor concentrations in treated wastewaters, a high activity of this ...
Klaus Fischer, Marion Wacht
doaj   +1 more source

Kinetic Model of Biphasic Character of Catalyse Inhibition

open access: yesNonlinear Analysis, 2003
A mathematical model of kinetics of fungal catalase inhibition with hydroxylamine in presence of substrate (hydrogen peroxide) has been developed. The scheme includes an intermediate formation and slow reversible native enzyme production.
J. Kulys   +2 more
doaj   +1 more source

Effect of Water Content on the Thermal Inactivation Kinetics of Horseradish Peroxidase Freeze-Dried from Alkaline pH

open access: yes, 2001
The thermal inactivation of horseradish peroxidase freeze-dried from solutions of different pH (8, 10 and 11.5, measured at 25 C) and equilibrated to different water contents was studied in the temperature range from 110 to 150 C.
Oliveira, J. C.   +2 more
core   +1 more source

Fungal Biotransformation of Chlordiazepoxide and Evaluation of Type and Kinetics of Fungal Enzyme

open access: yes, 2022
To produce an active metabolite of Chlordiazepoxide by fungal biotransformation in an easy and economic way and also to develop microbial models for drug metabolism studies.
M. Vidyavathi, M. Keerthana
core   +1 more source

Clinical and enzymatic phenotypes in congenital hyperinsulinemic hypoglycemia due to glucokinase‐activating mutations: A report of two cases and a brief overview of the literature

open access: yesJournal of Diabetes Investigation, 2019
Aims/Introduction The principal aim of this study was to investigate the clinical, genetic and functional characteristics of two cases of congenital hyperinsulinism (CHI) caused by glucokinase (GCK) mutations in young patients.
Fan Ping, Zhixin Wang, Xinhua Xiao
doaj   +1 more source

The origins of enzyme kinetics

open access: yesFEBS Letters, 2013
The equation commonly called the Michaelis–Menten equation is sometimes attributed to other authors. However, although Victor Henri had derived the equation from the correct mechanism, and Adrian Brown before him had proposed the idea of enzyme saturation, it was Leonor Michaelis and Maud Menten who showed that this mechanism could also be deduced on ...
openaire   +2 more sources

Modelling of Amperometric Biosensors in the Case of Substrate Inhibition

open access: yesSensors, 2006
The response of an amperometric biosensor at mixed enzyme kinetics anddiffusion limitations was modelled digitally in the case of substrate inhibition. Digitalsimulations were carried out using a finite difference technique.
Romas Baronas, Juozas Kulys
doaj   +1 more source

DENATURATION OF NATIVE AND DEGLYCOSYLATED α-GALACTOSIDASES FROM Penicillium canescens BY GUANIDINE HYDROCHLORIDE [PDF]

open access: yesBiotechnologia Acta, 2015
The aim of this work was the study of native and galactosidases from Penicillium canescens under denaturing conditions caused by guanidine hydrochloride.
Borzova N. V.
doaj   +1 more source

Kinetics and computational study of butyrylcholinesterase inhibition by methylrosmarinate: relevance to Alzheimer’s disease treatment

open access: yesHeliyon, 2022
Butyrylcholinesterase (BChE) performs a significant function in Alzheimer’s disease progression. Experimental studies have shown that the function of BChE in the attenuation of cholinergic neurotransmission is essentially altered in brains of advanced AD
Sani Muhammad Uzairu   +10 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

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