Results 111 to 120 of about 51,600 (308)
Journal of Ultrasound in Medicine, EarlyView.Objectives Intra‐amniotic sludge is an independent risk factor for preterm birth. It consists of a biophysical sonographic finding in the amniotic fluid, formed by dense echogenic particles near the cervical internal orifice, due to sterile or infectious inflammatory processes.
Clarissa Chavez Ortiz Roberto +8 more
wiley +1 more source
Eosinophilic fasciitis (Shulman's disease): review and comparative evaluation of seven patients. [PDF]
, 2019 OBJECTIVES: Eosinophilic fasciitis (EF) was described in 1974 by Shulman as a rare fibrosing connective tissue disease of unknown etiology. An undetermined trigger is thought to lead to the degranulation of eosinophils that interact with fibroblasts and
Cimbron, M +3 more
core +1 more source
Dupilumab and Systemic Hematologic Malignancies: Case Series and Literature Review
JEADV Clinical Practice, EarlyView.ABSTRACT Background Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting 15%–20% of children and 3%–10% of adults. An increased risk of systemic lymphomas – but not leukemias – has been reported in patients with AD. Dupilumab, a monoclonal IgG4 antibody targeting IL‐4 and IL‐13 signaling, is approved for moderate‐to‐severe AD and is ...
Nello Tommasino +3 more
wiley +1 more source
Level of Eosinophil Cationic Protein in Sputum of Chemical Warfare Victims [PDF]
Objective(s) Considering fair response to inhaled corticosteroids and reports of severe air way hyper responsiveness in chemical warfare victims (CWV), a role for eosinophilic inflammation (i.e. asthma) was postulated.
توحیدی, محمد +7 more
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Successful Treatment of Severe Adult Linear IgA Dermatosis Using Dupilumab
JEADV Clinical Practice, EarlyView.ABSTRACT Linear IgA dermatosis (LAD) is a rare autoimmune subepidermal bullous dermatosis, characterised by the presence of erythematous vesiculobullous lesions arranged in rosettes or herpetiform clusters. The standard treatment involves the administration of dapsone, followed by sulfasalazine, and general corticosteroid therapy, often in combination ...
Célia Delesalle +7 more
wiley +1 more source
TGFβ1 single-nucleotide polymorphism C-509T alters mucosal cell function in pediatric eosinophilic esophagitis. [PDF]
, 2020 Eosinophilic esophagitis (EoE) is a chronic Th2 antigen-driven disorder associated with tissue remodeling. Inflammation and remodeling lead to esophageal rigidity, strictures, and dysphagia. TGFβ1 drives esophageal remodeling including epithelial barrier
Aceves, SS +9 more
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The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Pediatric asthma is a common chronic airway inflammatory disease, where accurate assessment of disease severity and prognosis prediction is crucial for treatment decisions. Currently, there is a lack of precise and effective biomarkers.
Xu Yang +5 more
wiley +1 more source
Impact of Obesity on the Structured Histopathology of Chronic Rhinosinusitis Patients
The Laryngoscope, EarlyView.ABSTRACT Objectives Obesity is an established risk factor for asthma, which shares common inflammatory pathways with chronic rhinosinusitis (CRS). However, the link between obesity and CRS remains poorly understood. By identifying trends in the structured histopathology (SHP) of obese patients with CRS, we aim to better understand how changes in the ...
Daniel X. Ma +7 more
wiley +1 more source
Polyphenolic Activation of Basophils Explains Alcohol Hypersensitivity in AERD
The Laryngoscope, EarlyView.The mechanism behind alcohol sensitivity in AERD has not been previously characterized. This study demonstrates the activation of basophils in patients with CRSwNP and AERD by polyphenolic compounds, but not ethanol. Since these compounds can be found in alcoholic beverages in similar frequencies by which they trigger symptoms, this research provides a
Spencer C. Payne +3 more
wiley +1 more source
In utero ultrafine particulate matter exposure causes offspring pulmonary immunosuppression. [PDF]
, 2019 Early life exposure to fine particulate matter (PM) in air is associated with infant respiratory disease and childhood asthma, but limited epidemiological data exist concerning the impacts of ultrafine particles (UFPs) on the etiology of childhood ...
Chang, Richard C-A +15 more
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