Results 121 to 130 of about 31,457 (263)

Adipokines in Obese Asthma: A Complex Relationship Influenced More by Sex, Weight, and Oral Steroid Treatment Than Disease Severity

Allergy, EarlyView.
Adipokine secretion from adipose tissue may be involved in obesity‐related asthma, but it is unknown how adipokine levels relate to asthma characteristics. Plasma adipokines were measured in well‐characterized lean, overweight or obese patients with mild‐to‐moderate or severe asthma.
Lars I. Andersson, Maciej Kupczyk, Barbro Dahlén, Kenji Izuhara, Mina Gaga, Nikos M. Siafakas, Alberto Papi, Bianca Beghe, Guy Joos, Klaus F. Rabe, Elisabeth H. Bel, Sebastian L. Johnston, Pascal Chanez, Mark Gjomarkaj, Peter H. Howarth, Ewa Niżankowska‐Mogilnicka, Roelinde Middelveld, Sven‐Erik Dahlén, Apostolos Bossios, Anna James, on behalf of the BIOAIR (Longitudinal Assessment of Clinical Course and BIOmarkers in Severe Chronic AIRway Disease) and ChAMP consortia   +20 more
wiley   +1 more source

Predictive Factors And Treatments Associated with Clinical Remission in Severe Eosinophilic Asthma. [PDF]

J Inflamm Res
Lupia C, Marchi G, Chiarella E, Piazzetta GL, Lobello N, Crimi C, Poto R, Maglio A, Vatrella A, Pelaia G, Pelaia C.   +10 more
europepmc   +1 more source

Identification of Sub-Phenotypes of Eosinophilic Asthma: Eosinophilic Asthma Is Not Always Allergic Asthma [PDF]

Journal of Allergy and Clinical Immunology, 2017
Jamie Zacharias, Faoud Terrence Ishmael, Maria Henao, Efren L. Rael   +3 more
openaire   +1 more source

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, EarlyView.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source

Safety and effectiveness of benralizumab in Indian patients with severe eosinophilic asthma: results from the FAST study. [PDF]

Front Med (Lausanne)
Talwar D, Maturu VN, Meshram PL, Mittal S, Praveen JV, Guleria R, Kumar A, Agarwal A, Verma AK, Mohan M, Narasimhan R, Jain N, Sharma R, Kumar R, Parakh U, Momi G.   +15 more
europepmc   +1 more source

Polypropylene Nanoplastic Exposure to Respiratory Epithelial Barrier‐On‐Chip and Interfacial Interactions With Human Serum Albumin

Allergy, EarlyView.
Exposure to 305 nm PP NPs significantly disrupts the airway barrier‐on‐chip, reducing TEER, suppressing ZO‐1/ACE2 expression, and triggering ROS‐mediated apoptosis. In biological media, PP NPs exhibit a biphasic adsorption pattern, leading to the formation of a protein corona that increases their size to 364 nm.
Omur Sert, Eyup Bilgi, Reyhan Coban, Pelin Saglam‐Metiner, Basar Dogan, Zeynep Imir‐Tekneci, Suleyman Selim Cinaroglu, Ozlem Goksel, Ceyda Oksel Karakus, Ozlem Yesil‐Celiktas   +9 more
wiley   +1 more source

Desmoglein-2 dysregulation impairs epithelial barrier integrity in eosinophilic asthma. [PDF]

Respir Res
Yao L, Yuan X, Sun P, Fu H, Kermani NZ, Adcock IM, Liu Y, Jia M, Yao X.   +8 more
europepmc   +1 more source

Comparative efficacy of mepolizumab and benralizumab in severe eosinophilic asthma: a retrospective cohort study. [PDF]

BMC Pulm Med
Huang WC, Shen YL, Cheng WC, Huang CW, Chen CH, Tu CY, Hsu WH.   +6 more
europepmc   +1 more source

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

Allergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake, Alexandra C. Brown, Nikhil T. Awatade, Philip M. Hansbro, Katherine J. Baines, Richard Y. Kim, Nathan W. Bartlett, Jay C. Horvat, Peter A. B. Wark   +8 more
wiley   +1 more source

Unmasking Eosinophilic Granulomatosis with Polyangiitis: A Case of Rapid-Onset Myositis Following COVID-19 Booster in an Eosinophilic Asthma Patient. [PDF]

Eur J Rheumatol
Memdani A, Busa V, Avula S, Ford A, Nesheiwat J.   +4 more
europepmc   +1 more source