Results 211 to 220 of about 51,921 (307)

Polypropylene Nanoplastic Exposure to Respiratory Epithelial Barrier‐On‐Chip and Interfacial Interactions With Human Serum Albumin

Allergy, EarlyView.
Exposure to 305 nm PP NPs significantly disrupts the airway barrier‐on‐chip, reducing TEER, suppressing ZO‐1/ACE2 expression, and triggering ROS‐mediated apoptosis. In biological media, PP NPs exhibit a biphasic adsorption pattern, leading to the formation of a protein corona that increases their size to 364 nm.
Omur Sert, Eyup Bilgi, Reyhan Coban, Pelin Saglam‐Metiner, Basar Dogan, Zeynep Imir‐Tekneci, Suleyman Selim Cinaroglu, Ozlem Goksel, Ceyda Oksel Karakus, Ozlem Yesil‐Celiktas   +9 more
wiley   +1 more source

Reduced IL-10 production by FoxP3+IL-10+ Treg cells is partially compensated by complosome-associated induction of regulatory FoxP3-IL-10+ T cells in allergic eosinophilic asthma. [PDF]

Clin Exp Immunol
Stichova J, Slanina P, Chovancova Z, Baros J, Litzman M, Litzman J, Vlkova M.   +6 more
europepmc   +1 more source

Divergent Paths: A Comprehensive Review of Mechanisms and Clinical Implications in Atopic Dermatitis and Psoriasis

Allergy, EarlyView.
ABSTRACT Atopic dermatitis and psoriasis are two common cutaneous chronic inflammatory diseases. Although they share similar immunological mechanisms, their clinical implications in the patient are different. This review compares both diseases from different points of view such as genetics, natural history, triggers of disease, and skin barrier defects
Tali Czarnowicki, Kazunari Sugita, Zenas Yiu, Sandra Díez‐Ribas, Irene Garcia‐Jimenez, Emma Guttman‐Yassky, Luis F. Santamaria‐Babí   +6 more
wiley   +1 more source

Population Pharmacokinetics and Exposure-Response Analysis of Benralizumab in Chinese Adults, Adolescents, and Pediatric Participants with Severe Eosinophilic Asthma. [PDF]

Clin Pharmacokinet
Jin Y, Guiastrennec B, Stuke M, Yao Y, Zhang Y, Barker P, Jison M, Penland RC, Ding J, Lukka PB.   +9 more
europepmc   +1 more source

Anxiety, Depression, Schizophrenia, and Bipolar Disorder in Eosinophilic Esophagitis Patients: A Global Federated Cohort Analysis of Bidirectional Risks

Allergy, EarlyView.
Hui‐Chin Chang, Meng‐Che Wu, Torsten Zuberbier, Shuo‐Yan Gau   +3 more
wiley   +1 more source

Benralizumab and the integrated management of co-morbid severe eosinophilic asthma with chronic rhinosinusitis with nasal polyps. [PDF]

Clin Transl Allergy
Mullol J, D'Amato M, de Corso E, Han JK, Tversky J.   +4 more
europepmc   +1 more source

Prevalence of Type 2 Inflammation in Chronic Obstructive Pulmonary Disease Patients With Frequent Exacerbations

Allergy, EarlyView.
Mireille C. Melles, Johannes C. C. M. in 't Veen, Dirk‐Jan Slebos, Frits M. E. Franssen, Marlies van Dijk, Pieter‐Paul W. Hekking   +5 more
wiley   +1 more source

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

Allergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake, Alexandra C. Brown, Nikhil T. Awatade, Philip M. Hansbro, Katherine J. Baines, Richard Y. Kim, Nathan W. Bartlett, Jay C. Horvat, Peter A. B. Wark   +8 more
wiley   +1 more source

Effect of the Arg16Gly β₂-Adrenergic Receptor Polymorphism on Long-Term Mepolizumab Response and Clinical Remission in Severe Eosinophilic Asthma: A Genotype-Stratified, Multicenter Study. [PDF]

Allergy
Nolasco S, Fagone E, Campisi R, Portacci A, Scioscia G, Pelaia C, Maglio A, Candia C, Quaranta VN, Carrieri I, Saglia A, Vatrella A, Pelaia G, Vancheri C, Foschino Barbaro MP, D'Amato M, Carpagnano GE, Crimi N, Crimi C, Southern Italy Network on Severe Asthma Therapy.   +19 more
europepmc   +1 more source

Effects of azithromycin in severe eosinophilic asthma with concomitant monoclonal antibody treatment. [PDF]

Thorax
Lavoie G, Howell I, Melhorn J, Borg C, Bermejo-Sanchez L, Seymour J, Jabeen MF, Fries A, Hynes G, Pavord ID, Petousi N, Hinks TS.   +11 more
europepmc   +1 more source