Results 261 to 270 of about 51,600 (308)
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Eosinophilic Inflammation in Asthma
New England Journal of Medicine, 1990The importance of eosinophils in the pathogenesis of bronchial asthma is not established. In an attempt to evaluate the role of eosinophilic inflammation in asthma, we compared 10 normal subjects with 43 patients with chronic asthma, 19 of whom had severe disease as assessed by a clinical scoring method described by Aas and by pulmonary-function tests.
Jean Bousquet +10 more
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Eosinophil Inflammation in Asthma
American Journal of Respiratory and Critical Care Medicine, 1994Eosinophils were considered for many years to be cells protect ing against allergic inflammation because they release histamin ase or arylsulfatase that can counteract the effects of some dele terious mediators released by other cells of allergic inflammation.
J, Bousquet +4 more
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Eosinophilic Endotype of Asthma
Immunology and Allergy Clinics of North America, 2016Asthma is a heterogeneous disease that can be classified into different clinical endotypes, depending on the type of airway inflammation, clinical severity, and response to treatment. This article focuses on the eosinophilic endotype of asthma, which is defined by the central role that eosinophils play in the pathophysiology of the condition.
Fernando, Aleman +2 more
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Journal of Asthma, 1990
Regulation of eosinophils in man mast cells and eosinophils (abstract only) control of eosinophil production immunoglobulin-mediated activation of eosinophils lipid metabolism by eosinophils role of eosinophils chemotactic factors on eosinophil activation and leukotriene C4 production eosinophil heterogeneity changes in the number of hypodense ...
J. Morley, I. Colditz
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Regulation of eosinophils in man mast cells and eosinophils (abstract only) control of eosinophil production immunoglobulin-mediated activation of eosinophils lipid metabolism by eosinophils role of eosinophils chemotactic factors on eosinophil activation and leukotriene C4 production eosinophil heterogeneity changes in the number of hypodense ...
J. Morley, I. Colditz
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New England Journal of Medicine, 1991
To the Editor: Bousquet et al. (Oct. 11 issue)1 and others2 2345 report that there is a general association between numbers of eosinophils and the severity of asthma. Unfortunately, the controls for their bronchial-biopsy data1 may not have been appropriate, since material obtained post mortem ...
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To the Editor: Bousquet et al. (Oct. 11 issue)1 and others2 2345 report that there is a general association between numbers of eosinophils and the severity of asthma. Unfortunately, the controls for their bronchial-biopsy data1 may not have been appropriate, since material obtained post mortem ...
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Eosinophils in exercise-induced asthma
Journal of Allergy and Clinical Immunology, 1991The variations in serum levels of eosinophil cationic protein (ECP) have been measured after exercise challenge of 13 patients with asthma with exercise-induced asthma (EIA) and nine patients with asthma without EIA. The patients were treated before exercise in a randomized and blinded fashion with inhalation of one dose of either disodium ...
P, Venge, J, Henriksen, R, Dahl
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Archives of Internal Medicine, 1948
OF THE many diseases contracted by Americans in distant countries, tropical eosinophilic asthma seems to be the least known, as only 3 cases have been reported. 1 The subject of this study is a brief description of the disease and a report of 2 additional cases in which the condition had been treated as bronchial asthma for years and in which recovery ...
I, FOND, P, RAVENNA
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OF THE many diseases contracted by Americans in distant countries, tropical eosinophilic asthma seems to be the least known, as only 3 cases have been reported. 1 The subject of this study is a brief description of the disease and a report of 2 additional cases in which the condition had been treated as bronchial asthma for years and in which recovery ...
I, FOND, P, RAVENNA
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Eosinophils and Allergy in Asthma
Allergy and Asthma Proceedings, 1995Eosinophils are recruited to the site of IgE-mediated allergic reaction in the airway in asthma. Major eosinophil-chemotactic factors released from mast cells are platelet activating factor and Leukotriene B4. In addition, T cells and bronchial epithelial cells produce eosinophil chemotactic cytokines.
S, Makino, T, Fukuda
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2000
Bronchial hyperresponsiveness (BHR) to both specific and nonspecific stimuli is a characteristic feature of bronchial asthma. While the mechanisms underlying this exaggerated responsiveness are still unclear, there is a considerable body of evidence to suggest that mucosal inflammation of the airways is of central importance.
Anthony J. Coyle +1 more
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Bronchial hyperresponsiveness (BHR) to both specific and nonspecific stimuli is a characteristic feature of bronchial asthma. While the mechanisms underlying this exaggerated responsiveness are still unclear, there is a considerable body of evidence to suggest that mucosal inflammation of the airways is of central importance.
Anthony J. Coyle +1 more
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Annals of allergy, 1992
Eosinophils, a prominent feature of asthma, are found in increased numbers in the circulation and sputum, usually in relation to the severity of asthma. As a consequence of these clinical observations, investigators now speculate that the eosinophil has a central role in the pathogenesis of asthma.
W W, Busse, J B, Sedgwick
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Eosinophils, a prominent feature of asthma, are found in increased numbers in the circulation and sputum, usually in relation to the severity of asthma. As a consequence of these clinical observations, investigators now speculate that the eosinophil has a central role in the pathogenesis of asthma.
W W, Busse, J B, Sedgwick
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