Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice [PDF]
, 2016 Introduction: Liver X receptors (LXRs) are nuclear receptors that function as cholesterol sensors and regulate cholesterol homeostasis. High cholesterol has been recognized as a risk factor in asthma; however, the mechanism of this linkage is not known.
De Beuckelaer, Ans +10 more
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Eosinophilic Inflammation in Allergic Asthma [PDF]
Frontiers in Pharmacology, 2013 Eosinophils are circulating granulocytes involved in pathogenesis of asthma. A cascade of processes directed by Th2 cytokine producing T-cells influence the recruitment of eosinophils into the lungs. Furthermore, multiple elements including interleukin (IL)-5, IL-13, chemoattractants such as eotaxin, Clara cells, and CC chemokine receptor (CCR)3 are ...
Possa, Samantha S. +4 more
openaire +4 more sources
Severe eosinophilic bronchial asthma: new therapeutic options
Медицинский совет, 2018 Eosinophilic asthma is a common phenotype of severe asthma, occurring in at least half of patients. In recent years, there have been significant changes in the approaches to the treatment of severe bronchial asthma and, above all, eosinophilic asthma ...
N. M. Nenasheva
doaj +1 more source
Steroids in pediatric eosinophilic esophagitis [PDF]
, 2014 Swallowed fluticasone and oral viscous budesonide are effective first-line therapies for eosinophilic esophagitis in children. Side effects are minimal without evidence of Cushing syndrome, as seen in treatment with systemic corticosteroids.
Contreras, Emily M., Gupta, Sandeep K.
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Clinical characteristics of eosinophilic COPD versus COPD patients with a history of asthma
Respiratory Research, 2017 Eosinophilic COPD appears to be a distinct patient subgroup with an increased corticosteroid response. Eosinophilic COPD has been labelled as part of the asthma COPD overlap syndrome (ACOS).
Umme Kolsum +5 more
doaj +1 more source
Fasting impairs type 2 helper T cell infiltration in the lung of an eosinophilic asthma mouse model
FEBS Open Bio, 2021 Eosinophilic asthma is a form of bronchial asthma that is caused by the pulmonary infiltration of eosinophils and accounts for approximately half of the patients with severe asthma.
Yusuke Suzuki +7 more
doaj +1 more source
Utility of serum periostin in combination with exhaled nitric oxide in the management of asthma
Allergology International, 2017 Type-2/eosinophilic inflammation plays a pivotal role in asthma. The identification of severe type-2/eosinophilic asthma is important for improving the management of patients with asthma.
Tadao Nagasaki +19 more
doaj +1 more source
Asthma control and sputum eosinophils in adult patients: a cross-sectional study in southern Brazil
Scientific Reports, 2023 Asthma control and health related quality of life are an important goal of asthma management, but their association with sputum eosinophilic inflammation has been less firmly established.
Vanessa Albano Barcellos +3 more
doaj +1 more source
Development of eosinophilic pneumonia from eosinophilic bronchiolitis without asthma: A case report
Respiratory Medicine Case Reports, 2023 Eosinophilic bronchiolitis is a disease concept reported in Japan in 2001, that presents with bronchiolitis accompanied by eosinophilia in the blood and lungs.
Erika Mikami +8 more
doaj +1 more source
Reslizumab in patients with inadequately controlled late-onset asthma and elevated blood eosinophils [PDF]
, 2017 INTRODUCTION: Asthma with adult onset and elevated blood eosinophils is a difficult-to-treat subgroup. This post hoc analysis evaluated reslizumab, an anti-interleukin-5 monoclonal antibody, in patients with late-onset eosinophilic asthma.
Brusselle, Guy +3 more
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