Results 11 to 20 of about 136,090 (244)

Eosinophils in eosinophilic pneumonia [PDF]

open access: yesEuropean Respiratory Journal, 1996
Idiopathic eosinophilic pneumonia (IEP) is an uncom-mon disease of unknown aetiology characterized by theaccumulation of eosinophils in the lung, variable bloodeosinophilia and peripheral opacities on the chest radio-gram. The response to steroid treatment is dramatic butrelapses are frequent, requiring the use of long-termsteroid treatment [1 ...
ALBERA, Carlo, P. GHIO
openaire   +2 more sources

Eosinophilic esophagitis [PDF]

open access: yesCanadian Medical Association Journal, 2018
Eosinophilic esophagitis (EoE) is an atopic condition of the esophagus that has become increasingly recognized over the last 15 years. Diagnosis of the disorder is dependent on the patient’s clinical manifestations, and must be confirmed by histologic findings on esophageal mucosal biopsies.
Thurarshen, Jeyalingam, Samir C, Grover
  +10 more sources

Production of monoclonal antibodies reactive with ovine eosinophils

open access: yesBMC Immunology, 2007
Background There is strong evidence implicating eosinophils in host defence against parasites as well as allergic disease pathologies. However, a lack of reagents such as monoclonal antibodies (mAbs) specific for eosinophils has made it difficult to ...
Meeusen Els NT   +3 more
doaj   +1 more source

Eosinophils, beyond IL-5

open access: yesCells, 2021
New therapeutic monoclonal antibodies targeting the IL-5/IL-5 receptor pathway are extremely efficient in depleting blood eosinophils from subjects with asthma [...]
Stephane Esnault   +2 more
doaj   +1 more source

Dual function of eosinophils in pathogenesis and protective immunity against parasites

open access: yesMemorias do Instituto Oswaldo Cruz, 1992
The functional duality of eosinophils, involved in a protective response or in pathogenesis is illustrated in various parasitic infections. In schistosomiasis, eosinophils have been shown to mediate schistosomula killing, in the presence of antibodies ...
Monique Capron
doaj   +1 more source

Eosinophilic pneumonias

open access: yesAllergy, 2005
Eosinophilic pneumonias (EP) encompass a wide spectrum of lung diseases characterized by peripheral blood eosinophilia (>1 × 109 eosinophils/l) and/or alveolar eosinophilia (>25%). Blood eosinophilia may be lacking, as in the early phase of idiopathic acute EP, or in patients already taking oral corticosteroids.
Cottin, Vincent, Cordier, Jean-François
openaire   +4 more sources

Eosinophilic leukaemia [PDF]

open access: yesBritish Medical Bulletin, 2007
The last few years have seen much progress in our understanding of, and treatments for, eosinophilic leukaemia. In preparing this review, we used Pubmed and the archives of well-known Haematology journals to search for relevant research papers and reviews published in the last 5-10 years.
Sarah, Fletcher, Barbara, Bain
openaire   +2 more sources

Anti-IL5 Drugs in COVID-19 Patients: Role of Eosinophils in SARS-CoV-2-Induced Immunopathology

open access: yesFrontiers in Pharmacology, 2021
SARS-CoV-2 infection stimulates a complex activation of the immune system. Eosinophils belong to the host’s defense equipment against respiratory viruses.
Daniele Pala   +3 more
doaj   +1 more source

Prostaglandin D2 and Interleukin-5 Reduce Crth2 Surface Expression on Human Eosinophils

open access: yesAllergology International, 2004
Background: Recently, a second prostaglandin D2 (PGD2) receptor, chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2), was identified.
Kazuyuki Hamada   +11 more
doaj   +1 more source

Autophagy Protects against Eosinophil Cytolysis and Release of DNA

open access: yesCells, 2022
The presence of eosinophils in the airway is associated with asthma severity and risk of exacerbations. Eosinophils deposit their damaging products in airway tissue, likely by degranulation and cytolysis.
Stephane Esnault   +8 more
doaj   +1 more source

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