Results 11 to 20 of about 232,004 (343)
Epigenetic and transcriptional programming of murine eosinophils in the esophagus [PDF]
Nature CommunicationsEosinophils accumulate in different tissues in allergies, cancer, and infectious diseases, adopting distinct properties. Herein, we profiled murine esophageal eosinophils during allergic inflammation using single-cell sequencing, epigenomic mapping, and ...
Jennifer M. Felton +19 more
doaj +2 more sources
Frontiers in Medicine, 2018 Bullous pemphigoid (BP) is an autoimmune blistering disease which carries a significant mortality and morbidity. While historically BP has been characterized as an IgG driven disease mediated by anti-BP180 and BP230 IgG autoantibodies, developments in ...
Kyle T. Amber +4 more
doaj +2 more sources
Allergy. European Journal of Allergy and Clinical Immunology, 2023 Eosinophils are bone marrow‐derived granulocytes and are found in low numbers in the peripheral blood of healthy subjects. In type 2 inflammatory diseases, eosinopoiesis in the bone marrow is increased, resulting in a rise in the number of mature ...
Lea Gigon +4 more
semanticscholar +1 more source
Allergology International, 2021 Eosinophils not only play a critical role in the pathogenesis of eosinophil-associated diseases, but they also have multiple important biological functions, including the maintenance of homeostasis, host defense against infections, immune regulation ...
Akira Kanda +10 more
doaj +1 more source
Active eosinophils regulate host defence and immune responses in colitis
Nature, 2022 Single-cell transcriptomic profiling and functional assays are used to identify subpopulations of eosinophils that are present in the mouse gastrointestinal tract and provide insight into the role of these cells in inflammatory bowel diseases in humans ...
Alessandra Gurtner +20 more
semanticscholar +1 more source
Frontiers in Immunology, 2021 Eosinophils are multifunctional, evolutionary conserved leukocytes that are involved in a plethora of responses ranging from regulation of tissue homeostasis to host defense and cancer.
Avishay Dolitzky +8 more
doaj +1 more source
Annual Review of Immunology, 2021 The enigmatic eosinophil has emerged as an exciting component of the immune system, involved in a plethora of homeostatic and inflammatory responses. Substantial progress has been achieved through experimental systems manipulating eosinophils in vivo ...
E. Jacobsen +8 more
semanticscholar +1 more source
Eosinophils in eosinophilic pneumonia [PDF]
European Respiratory Journal, 1996 Idiopathic eosinophilic pneumonia (IEP) is an uncom-mon disease of unknown aetiology characterized by theaccumulation of eosinophils in the lung, variable bloodeosinophilia and peripheral opacities on the chest radio-gram. The response to steroid treatment is dramatic butrelapses are frequent, requiring the use of long-termsteroid treatment [1 ...
ALBERA, Carlo, P. GHIO
openaire +2 more sources
Eosinophilic esophagitis [PDF]
Canadian Medical Association Journal, 2018 Eosinophilic esophagitis (EoE) is an atopic condition of the esophagus that has become increasingly recognized over the last 15 years. Diagnosis of the disorder is dependent on the patient’s clinical manifestations, and must be confirmed by histologic findings on esophageal mucosal biopsies.
Thurarshen, Jeyalingam, Samir C, Grover
+10 more sources
Metastasis-Entrained Eosinophils Enhance Lymphocyte-Mediated Antitumor Immunity
Cancer Research, 2021 These findings demonstrate antitumor activities of eosinophils in the metastatic tumor microenvironment, suggesting that harnessing eosinophil activity may be a viable clinical strategy in patients with cancer.
A. Munitz +23 more
semanticscholar +1 more source