Results 21 to 30 of about 232,004 (343)
Differential regulation of Type 1 and Type 2 mouse eosinophil activation by apoptotic cells
Frontiers in Immunology, 2022 Eosinophils are multifunctional, evolutionary conserved leukocytes that are involved in a plethora of responses ranging from regulation of tissue homeostasis, host defense and cancer. Although eosinophils have been studied mostly in the context of Type 2
Avishay Dolitzky +8 more
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Eosinophils: A Friend or Foe in human health and diseases
Kidney Diseases, 2022 Since their discovery, around 150 years, eosinophils research has been a field of changing perspective, and new directions are emerging since then. Initially, eosinophils were perceived as terminally-differentiated cytotoxic effector cells.
Madiha Zahra Syeda +4 more
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Contributions of Eosinophils to Human Health and Disease.
Annual Review of Pathology, 2020 The human eosinophil has long been thought to favorably influence innate mucosal immunity but at times has also been incriminated in disease pathophysiology.
A. Klion, S. Ackerman, B. Bochner
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Dermatomyositis with Eosinophils
Dermatopathology, 2023 Dermatomyositis is an idiopathic inflammatory myopathy that often presents with symmetric proximal skeletal muscle weakness and characteristic skin findings. Typical skin biopsy findings include vacuolar changes of the basal layer, increased dermal mucin,
Isabella I. Sanchez +4 more
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Eosinophils Decrease Pulmonary Metastatic Mammary Tumor Growth
Frontiers in Oncology, 2022 Metastatic breast cancer is challenging to effectively treat, highlighting the need for an improved understanding of host factors that influence metastatic tumor cell colonization and growth in distant tissues.
Rachel A. Cederberg +17 more
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Role of IL-25 on Eosinophils in the Initiation of Th2 Responses in Allergic Asthma
Frontiers in Immunology, 2022 BackgroundEosinophils act as a secondary antigen-presenting cell (APC) to stimulate Th cell responses against antigens. IL-25 plays a significant role in eosinophil activation in allergic asthma.
Bo Peng +19 more
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CD44 on blood eosinophils as a novel marker of bronchial asthma management
Allergology International, 1998 Bronchial asthma (BA) is characterized by infiltration of the respiratory tracts by eosinophils. A wide variety of adhesion molecules is involved in the binding of eosinophils to the vascular endothelium and their subsequent transmigration from the ...
Kunio Sano +5 more
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Pharmacology Research & Perspectives, 2020 Acute respiratory virus infections, such as influenza and RSV, are predominant causes of asthma exacerbations. Eosinophils act as a double‐edged sword in exacerbations in that they are activated by viral infections but also can capture and inactivate ...
Yanaika Shari Sabogal Piñeros +8 more
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Cells, 2021 New therapeutic monoclonal antibodies targeting the IL-5/IL-5 receptor pathway are extremely efficient in depleting blood eosinophils from subjects with asthma [...]
Stephane Esnault +2 more
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Production of monoclonal antibodies reactive with ovine eosinophils
BMC Immunology, 2007 Background There is strong evidence implicating eosinophils in host defence against parasites as well as allergic disease pathologies. However, a lack of reagents such as monoclonal antibodies (mAbs) specific for eosinophils has made it difficult to ...
Meeusen Els NT +3 more
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