Results 21 to 30 of about 229,703 (354)

Nasal histamine responses in nonallergic rhinitis with eosinophilic syndrome [PDF]

, 2015
Background: Nonallergic rhinitis with eosinophilic syndrome (NARES) is persistent, without atopy, but with ≥25% nasal eosinophilia. Hypereosinophilia seems to contribute to nasal mucosa dysfunction.
Ciofalo, Andrea, de Vincentiis, Marco, Fusconi, Massimo, Greco, Antonio, Magliulo, Giuseppe, Romeo, Raffaello, Soldo, Pietro, Zambetti, Giampietro   +7 more
core   +1 more source

Production of monoclonal antibodies reactive with ovine eosinophils

BMC Immunology, 2007
Background There is strong evidence implicating eosinophils in host defence against parasites as well as allergic disease pathologies. However, a lack of reagents such as monoclonal antibodies (mAbs) specific for eosinophils has made it difficult to ...
Meeusen Els NT, Young Anna R, Sansome Georgina M, Bischof Robert J   +3 more
doaj   +1 more source

Phosphodiesterase 4 inhibitors attenuate virus‐induced activation of eosinophils from asthmatics without affecting virus binding

Pharmacology Research & Perspectives, 2020
Acute respiratory virus infections, such as influenza and RSV, are predominant causes of asthma exacerbations. Eosinophils act as a double‐edged sword in exacerbations in that they are activated by viral infections but also can capture and inactivate ...
Yanaika Shari Sabogal Piñeros, Tamara Dekker, Barbara Smids, Christof J. Majoor, Lara Ravanetti, Gino Villetti, Maurizio Civelli, Fabrizio Facchinetti, René Lutter   +8 more
doaj   +1 more source

Autophagy Protects against Eosinophil Cytolysis and Release of DNA

Cells, 2022
The presence of eosinophils in the airway is associated with asthma severity and risk of exacerbations. Eosinophils deposit their damaging products in airway tissue, likely by degranulation and cytolysis.
Stephane Esnault, Paul S. Fichtinger, Karina T. Barretto, Frances J. Fogerty, Ksenija Bernau, Deane F. Mosher, Sameer K. Mathur, Nathan Sandbo, Nizar N. Jarjour   +8 more
doaj   +1 more source

The multiple functions and subpopulations of eosinophils in tissues under steady-state and pathological conditions

Allergology International, 2021
Eosinophils not only play a critical role in the pathogenesis of eosinophil-associated diseases, but they also have multiple important biological functions, including the maintenance of homeostasis, host defense against infections, immune regulation ...
Akira Kanda, Yasutaka Yun, Dan Van Bui, Linh Manh Nguyen, Yoshiki Kobayashi, Kensuke Suzuki, Akitoshi Mitani, Shunsuke Sawada, Satoko Hamada, Mikiya Asako, Hiroshi Iwai   +10 more
doaj  

Eosinophils, Stroke-Associated Pneumonia, and Outcome After Mechanical Thrombectomy for Acute Ischemic Stroke

Frontiers in Aging Neuroscience, 2022
BackgroundEosinophils contribute to antibacterial defense by releasing mitochondrial DNA, which are decreased in patients with acute ischemic stroke (AIS).
Zhiliang Guo, Jie Hou, Shuai Yu, Hang Zhang, Shuhong Yu, Huaishun Wang, Jiaping Xu, Shoujiang You, Zhichao Huang, Guodong Xiao, Yongjun Cao, Chun-Feng Liu   +11 more
doaj   +1 more source

A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo. [PDF]

, 1993
Using an in vivo test system, the role of the β1 integrin very late activation antigen-4 (VLA-4) in eosinophil accumulation in allergic and nonallergic inflammatory reactions was investigated.
Lobb, RR, Nourshargh, S, Weg, VB, Williams, TJ   +3 more
core   +1 more source

Dual function of eosinophils in pathogenesis and protective immunity against parasites

Memorias do Instituto Oswaldo Cruz, 1992
The functional duality of eosinophils, involved in a protective response or in pathogenesis is illustrated in various parasitic infections. In schistosomiasis, eosinophils have been shown to mediate schistosomula killing, in the presence of antibodies ...
Monique Capron
doaj   +1 more source

Anti-IL5 Drugs in COVID-19 Patients: Role of Eosinophils in SARS-CoV-2-Induced Immunopathology

Frontiers in Pharmacology, 2021
SARS-CoV-2 infection stimulates a complex activation of the immune system. Eosinophils belong to the host’s defense equipment against respiratory viruses.
Daniele Pala, Daniele Pala, Marco Pistis, Marco Pistis   +3 more
doaj   +1 more source

Tissue eosinophilia and eosinophil degranulation in Riedel's invasive fibrous thyroiditis. [PDF]

, 1996
The etiology of Riedel's invasive fibrous thyroiditis (IFT) has remained obscure. This rare disorder has been confused in the past with the more common fibrous variant of Hashimoto's disease.
Bahn, R. S., Gleich, G. J., Goellner, J. R., Hay, I. D., Heufelder, Armin E.   +4 more
core   +1 more source