Results 21 to 30 of about 212,373 (377)
A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo. [PDF]
Using an in vivo test system, the role of the β1 integrin very late activation antigen-4 (VLA-4) in eosinophil accumulation in allergic and nonallergic inflammatory reactions was investigated.
Lobb, RR+3 more
core +1 more source
Autophagy Protects against Eosinophil Cytolysis and Release of DNA
The presence of eosinophils in the airway is associated with asthma severity and risk of exacerbations. Eosinophils deposit their damaging products in airway tissue, likely by degranulation and cytolysis.
Stephane Esnault+8 more
doaj +1 more source
Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1 [PDF]
Galectin-1 (Gal-1), a glycan-binding protein with broad antiinflammatory activities, functions as a proresolving mediator in autoimmune and chronic inflammatory disorders. However, its role in allergic airway inflammation has not yet been elucidated.
Abramoff+15 more
core +1 more source
Eosinophilic Gastroenteritis with Eosinophilic Dermatitis
Eosinophilic gastroenteritis (EG) is characterized by eosinophilic infiltration of the bowel wall and variable gastrointestinal manifestations. Clinicians should have a high index of suspicion for EG when faced with gastrointestinal symptoms and peripheral eosinophilia to avoid incorrect diagnosis and inappropriate treatments.
Jae Myung Cha+3 more
openaire +3 more sources
Production of monoclonal antibodies reactive with ovine eosinophils
Background There is strong evidence implicating eosinophils in host defence against parasites as well as allergic disease pathologies. However, a lack of reagents such as monoclonal antibodies (mAbs) specific for eosinophils has made it difficult to ...
Meeusen Els NT+3 more
doaj +1 more source
Acute respiratory virus infections, such as influenza and RSV, are predominant causes of asthma exacerbations. Eosinophils act as a double‐edged sword in exacerbations in that they are activated by viral infections but also can capture and inactivate ...
Yanaika Shari Sabogal Piñeros+8 more
doaj +1 more source
BackgroundEosinophils contribute to antibacterial defense by releasing mitochondrial DNA, which are decreased in patients with acute ischemic stroke (AIS).
Zhiliang Guo+11 more
doaj +1 more source
High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability. [PDF]
The development of intestinal permeability and the penetration of microbial products are key factors associated with the onset of metabolic disease. However, the mechanisms underlying this remain unclear. Here we show that, unlike liver or adipose tissue,
Armando, Aaron M+6 more
core +2 more sources
Abstract Background Patients with chronic rhinosinusitis (CRS) may have persistence of polyps, discharge, or edema after endoscopic sinus surgery (ESS). Inflammation in CRS can be classified into three endotypes, with the presence of polyps associated with the type 2 endotype.
Eli Stein+12 more
wiley +1 more source
Eosinophils not only play a critical role in the pathogenesis of eosinophil-associated diseases, but they also have multiple important biological functions, including the maintenance of homeostasis, host defense against infections, immune regulation ...
Akira Kanda+10 more
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