Results 41 to 50 of about 234,859 (336)

CD69 Signaling in Eosinophils Induces IL-10 Production and Apoptosis via the Erk1/2 and JNK Pathways, Respectively

Biomolecules
Introduction: Eosinophils contribute to the pathogenesis of allergic diseases, including asthma, allergic rhinitis, and atopic dermatitis. We previously reported that human tissue eosinophils have high CD69 expression compared to blood eosinophils, and ...
Dan Van Bui, Linh Manh Nguyen, Akira Kanda, Hanh Hong Chu, Nhi Kieu Thi Le, Yasutaka Yun, Yoshiki Kobayashi, Kensuke Suzuki, Akitoshi Mitani, Akihiro Shimamura, Kenta Fukui, Shunsuke Sawada, David Dombrowicz, Hiroshi Iwai   +13 more
doaj   +1 more source

CCR8 leads to eosinophil migration and regulates neutrophil migration in murine allergic enteritis [PDF]

, 2019
Allergic enteritis (AE) is a gastrointestinal form of food allergy. This study aimed to elucidate cellular and molecular mechanisms of AE using a murine model. To induce AE, BALB/c wild type (WT) mice received intraperitoneal sensitization with ovalbumin
Blanco Pérez, Frank, Burggraf, Manja, Gonzalez Menendez, Irene, Iwakura, Yoichiro, Kato, Yoichiro, Kirberg, Jörg, Krause, Maren, Laiño, Jonathan Emiliano, Martella, Manuela, Ohbayashi, Masaharu, Quintanilla Martinez, Leticia, Scheurer, Stephan, Shibata, Noriyuki, Toda, Masako, Vieths, Stefan   +14 more
core   +1 more source

Eosinophilic pneumonias

Allergy, 2005
Eosinophilic pneumonias (EP) encompass a wide spectrum of lung diseases characterized by peripheral blood eosinophilia (>1 × 109 eosinophils/l) and/or alveolar eosinophilia (>25%). Blood eosinophilia may be lacking, as in the early phase of idiopathic acute EP, or in patients already taking oral corticosteroids.
Romain Lazor, Jean-François Cordier, Cottin   +2 more
openaire   +5 more sources

Association between fractional exhaled nitric oxide, sputum induction and peripheral blood eosinophil in uncontrolled asthma

Allergy, Asthma & Clinical Immunology, 2018
Background The fractional exhaled nitric oxide (FeNO) and blood eosinophils are biomarkers of eosinophilic airway inflammation used in the diagnosis and management of asthma, although induced sputum is the gold standard test for phenotypic asthma ...
Jie Gao, Feng Wu
doaj   +1 more source

Recent advances of eosinophils and its correlated diseases

Frontiers in Public Health, 2022
Eosinophils are differentiated by bone marrow multipotent progenitor cells and are further released into peripheral blood after maturation. Human eosinophils can exhibit unique multi-leaf nuclear morphology, which are filled with cytoplasmic granules ...
Zhang Tao, Hua Zhu, Hua Zhu, Jiateng Zhang, Jiateng Zhang, Zhiming Huang, Zhiming Huang, Ze Xiang, Ze Xiang, Tu Hong, Tu Hong   +10 more
doaj   +1 more source

Eosinophils Exert Antitumorigenic Effects in the Development of Esophageal Squamous Cell CarcinomaSummary

Cellular and Molecular Gastroenterology and Hepatology, 2023
Background and Aims: Eosinophils are present in several solid tumors and have context-dependent function. Our aim is to define the contribution of eosinophils in esophageal squamous cell carcinoma (ESCC), as their role in ESCC is unknown.
Justin Jacobse, Zaryab Aziz, Lili Sun, Jasmine Chaparro, Jennifer M. Pilat, Aaron Kwag, Matthew Buendia, Mae Wimbiscus, Motomi Nasu, Tsuyoshi Saito, Shinji Mine, Hajime Orita, Frank Revetta, Sarah P. Short, M. Kay Washington, Girish Hiremath, Michael K. Gibson, Lori A. Coburn, Tatsuki Koyama, Jeremy A. Goettel, Christopher S. Williams, Yash A. Choksi   +21 more
doaj   +1 more source

Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants. [PDF]

, 2013
A locus on human chromosome 11q23 tagged by marker rs3802842 was associated with colorectal cancer (CRC) in a genome-wide association study; this finding has been replicated in case-control studies worldwide. In order to identify biologic factors at this
Ash, Colleen, Beck, Timothy, Bielecki, Ryszard, Boutros, Paul C, Chan-Seng-Yue, Michelle, Chong, Taryne, D'Souza, David JA, De Borja, Richard, Dick, John E, Gallinger, Steven, Gryfe, Robert, Hodgson, Lyndsey, Hudson, Thomas J, Kozak, Krystian, Kwan, Jennifer YY, Lee, Shawna, Lemire, Mathieu, McPherson, John D, Peltekova, Vanya D, Pollett, Aaron, Qazi, Aamer M, Rangrej, Jagadish, Rogers, Marianne, Stein, Lincoln D, Timms, Lee, Trinh, Quang M, Volar, Milica, Wang, Jianxin, Wang, Mike, Zaidi, Syed HE, Zandi, Sasan, Zanke, Brent W   +31 more
core   +2 more sources

Do blood eosinophils strictly reflect airway inflammation in COPD? Comparison with asthmatic patients

Respiratory Research, 2019
Introduction Airway eosinophilic inflammation is a characteristic of asthmatic patients and of a sub group of COPD subjects. Blood eosinophils are deemed as a good surrogate marker of sputum eosinophilic inflammation; however, controversial data have ...
Patrizia Pignatti, Dina Visca, Francesca Cherubino, Elisabetta Zampogna, Etienne Lucini, Laura Saderi, Giovanni Sotgiu, Antonio Spanevello   +7 more
doaj   +1 more source

気管支喘息における気管支肺胞洗浄液中の細胞成分に対する加齢および副腎皮質ホルモンの影響 [PDF]

, 2002
Effects of aging and glucocorticoid therapy on bronchoalveolar lavage (BAL) cells, particularly lymphocytes, neutrophils and eosinophils, were examined in 81 patients with asthma. 1.
Ashida, Kozo, Hosaki, Yasuhiro, Mitsunobu, Fumihiro, Nishida, Norikazu, Okamoto, Makoto, Takata, Shingo, Tanizaki, Yoshiro, Tsugeno, Hirofumi, Yokoi, Tadashi   +8 more
core   +1 more source

Functional and phenotypic evaluation of eosinophils from patients with the acute form of paracoccidioidomycosis. [PDF]

PLoS Neglected Tropical Diseases, 2017
Eosinophilia is a typical finding of the acute/juvenile form of paracoccidioidomycosis (PCM), a systemic mycosis endemic in Latin America. This clinical form is characterized by depressed cellular immune response and production of Th2 cytokines. Moreover,
Fernanda Gambogi Braga, Luciana Pereira Ruas, Ricardo Mendes Pereira, Xinaida Taligare Lima, Edson Antunes, Ronei Luciano Mamoni, Maria Heloisa Souza Lima Blotta   +6 more
doaj   +1 more source