Results 61 to 70 of about 24,385 (192)

Ascending central canal dilation and progressive ependymal disruption in a contusion model of rodent chronic spinal cord injury

BMC Neurology, 2007
Background Chronic spinal cord injury (SCI) can lead to an insidious decline in motor and sensory function in individuals even years after the initial injury and is accompanied by a slow and progressive cytoarchitectural destruction.
Keirstead Hans S, Nistor Gabriel, Radojicic Milan   +2 more
doaj   +1 more source

Wasteosomes accumulate in periventricular white matter hyperintensities and exhibit complex relationships with mixed pathology, sclerotic index, and perivascular space

Brain Pathology, EarlyView.
In a mixed diagnostic cohort of pathologically diagnosed Alzheimer's disease, cerebrovascular disease, mixed pathology, and control tissue, we connected the histopathological wasteosome profile in periventricular (PV) brain sections to 7T FLAIR‐MRI confirmed PV white matter hyperintensities (WMHs), vascular stenosis and perivascular space size ...
Nikita Ollen‐Bittle, Isabella Boesgaard, Austyn Roseborough, Meaghan Frank, Qi Zhang, Stephen H. Pasternak, Robert Hammond, Shawn N. Whitehead   +7 more
wiley   +1 more source

Pathogenesis of cerebral malformations in human fetuses with meningomyelocele

Cerebrospinal Fluid Research, 2008
Background Fetal spina bifida aperta (SBA) is characterized by a spinal meningomyelocele (MMC) and associated with cerebral pathology, such as hydrocephalus and Chiari II malformation.
Brouwer Oebele F, Meiners Linda C, Muñoz Rosa, Sollie Krystyne M, den Dunnen Wilfred FA, de Wit Olga A, Rodríguez Esteban M, Sival Deborah A   +7 more
doaj   +1 more source

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for ependymomas

Brain Pathology, EarlyView.
Adapting Diagnostic Approaches for Practical Taxonomy in Resource‐Restrained Regions (ADAPTR) recommendations for ependymomas in resource‐restrained settings (RL = resource level; created in BioRender). Abstract Ependymomas are uncommon primary tumors of the central nervous system (CNS) that affect both children and adults.
Laveniya Satgunaseelan, Michael E. Buckland, Geeta Chacko, Kenta Masui, Junji Shibahara, Vani Santosh, Maysa Al‐Hussaini, Sung‐Hye Park, Tarik Tihan, Ho‐Keung Ng, Pieter Wesseling, David N. Louis, Chitra Sarkar, Takashi Komori   +13 more
wiley   +1 more source

The ependymal cell layer in the SEZ is functionally hypoxic.

, 2013
(A–B) High magnification views of the ependymal cell layer (A) and underlying SEZ (B) confirmed that Hypoxyprobe-1 (hpi) staining was specific to the ependymal layer and not to the underlying tissue.
James C. Culver (109018), Tegy J. Vadakkan (91345), Mary E. Dickinson (91346)   +2 more
core   +1 more source

Ependymal cells: roles in central nervous system infections and therapeutic application

Journal of Neuroinflammation
Ependymal cells are arranged along the inner surfaces of the ventricles and the central canal of the spinal cord, providing anatomical, physiological and immunological barriers that maintain cerebrospinal fluid (CSF) homeostasis.
Shiqi Xie, Feng Li
doaj   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) CM de Lange   +26 more
wiley   +1 more source

Glucocorticoids Target Ependymal Glia and Inhibit Repair of the Injured Spinal Cord

Frontiers in Cell and Developmental Biology, 2019
Following injury, the mammalian spinal cord forms a glial scar and fails to regenerate. In contrast, vertebrate fish spinal cord tissue regenerates significantly to restore function.
Craig M. Nelson, Craig M. Nelson, Vanda A. Lennon, Vanda A. Lennon, Vanda A. Lennon, Han Lee, Randall G. Krug, Aichurok Kamalova, Nicolas N. Madigan, Karl J. Clark, Anthony J. Windebank, John R. Henley, John R. Henley   +12 more
doaj   +1 more source

Acute viral encephalitis impacts dense‐core amyloid plaque pathology and dysregulates myeloid responses to amyloid plaques

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION Recent epidemiological datasets have associated viral encephalitis exposure (i.e., viral‐induced neuroinflammation) with increased risk of Alzheimer's disease (AD) and dementia, highlighting the need to uncover how it may impact AD neuropathology.
Dominic Ibarra Javonillo, Susana Furman, Lucas Le, Kellie Fernandez, Jazmyn Mulford, Vidushi Singla, Roshni Jha, Kate Inman Tsourmas, Nellie E. Kwang, Kim N. Green, Thomas E. Lane   +10 more
wiley   +1 more source

Correlative scanning and transmission electron microscopic study on the ependymal surface of Bradypus Tridactylus

Arquivos de Neuro-Psiquiatria, 1983
Topographical variations of the ependymal surface of the whole brain ventricular system of Bradypus tridactylus were studied at the scanning electron microscope after CO2 critical point drying and carbon-gold coating.
Claudio A. Ferraz de Carvalho, Cláudio Fava Chagas, Ciro Ferreira da Silva, Francisco Prado Reis   +3 more
doaj   +1 more source