Results 131 to 140 of about 24,553 (253)

PDGFRα+ Cells in Embryonic Stem Cell Cultures Represent the In Vitro Equivalent of the Pre-implantation Primitive Endoderm Precursors

Stem Cell Reports, 2017
In early mouse pre-implantation development, primitive endoderm (PrE) precursors are platelet-derived growth factor receptor alpha (PDGFRα) positive. Here, we demonstrated that cultured mouse embryonic stem cells (mESCs) express PDGFRα heterogeneously ...
Antonio Lo Nigro, Anchel de Jaime-Soguero, Rita Khoueiry, Dong Seong Cho, Giorgia Maria Ferlazzo, Ilaria Perini, Vanesa Abon Escalona, Xabier Lopez Aranguren, Susana M. Chuva de Sousa Lopes, Kian Peng Koh, Pier Giulio Conaldi, Wei-Shou Hu, An Zwijsen, Frederic Lluis, Catherine M. Verfaillie   +14 more
doaj   +1 more source

Tracing blastomere fate choices of early embryos in single cell culture [PDF]

, 2010
Blastomeres of early vertebrate embryos undergo numerous fate choices for division, motility, pluripotency maintenance and restriction culminating in various cell lineages.
Chang Ming Li, Haobin Zhao, Jianxin Song, Meisheng Yi, Mingyou Li, Ni Hong, Rong Liu, Ruowen Ge, Yan Yan, Yongming Yuan, Yunhan Hong, Zhendong Li   +11 more
core   +1 more source

Pluripotency Potential of Embryonic Stem Cell-Like Cells Derived from Mouse Testis

Cell Journal, 2019
Objective: During the cultivation of spermatogonial stem cells (SSCs) and their conversion into embryonic stem-like (ES-like) cells, transitional ES-like colonies and epiblast-like cells were observable.
Hossein Azizi, Behruz Asgari, Thomas Skutella   +2 more
doaj   +1 more source

X-chromosome inactivation mosaicism in the three germ layers and the germ line of the mouse embryo [PDF]

, 1982
Electrophoretic variant forms of the X-linked enzyme phosphoglycerate kinase (PGK-1, E.C.2, 7, 2, 3) have been used to examine X-chromosome mosaicism in tissues from 121/2-day post coitum heterozygous female mouse embryos.
Fosten, M., McMahon, A., Monk, M.
core  

Requirements for efficient cell-type proportioning: regulatory timescales, stochasticity and lateral inhibition

, 2015
The proper functioning of multicellular organisms requires the robust establishment of precise proportions between distinct cell-types. This developmental differentiation process typically involves intracellular regulatory and stochastic mechanisms to ...
Kaneko, Kunihiko, Pfeuty, Benjamin
core   +1 more source

epiblast

Citation: 'epiblast' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10664 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial usage
openaire   +1 more source

Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency

Nature Communications, 2016
Known molecular determinants of developmental plasticity are mainly transcription factors, while the extrinsic regulation of this process has been largely unexplored. Here we identify Cripto as one of the earliest epiblast markers and a key extracellular
Alessandro Fiorenzano, Emilia Pascale, Cristina d’Aniello, D. Acampora, Cécilia Bassalert, Francesco Russo, Gennaro Andolfi, M. Biffoni, Federica Francescangeli, A. Zeuner, C. Angelini, C. Chazaud, E. Patriarca, A. Fico, G. Minchiotti   +14 more
semanticscholar   +1 more source

Single-Cell RNA-Seq Reveals Cellular Heterogeneity of Pluripotency Transition and X Chromosome Dynamics during Early Mouse Development

Cell Reports, 2019
Summary: Following implantation, the epiblast (EPI) cells transit from the naive to primed pluripotency, accompanied by dynamic changes in X chromosome activity in females. To investigate the molecular attributes of this process, we performed single-cell
Shangli Cheng, Yu Pei, Liqun He, Guangdun Peng, Björn Reinius, Patrick P.L. Tam, Naihe Jing, Qiaolin Deng   +7 more
doaj   +1 more source

Integrin and dystroglycan compensate each other to mediate laminin-dependent basement membrane assembly and epiblast polarization

Matrix Biology, 2016
During early embryogenesis, endodermal γ1-laminin expression is required for basement membrane (BM) assembly, promoting conversion of non-polar pluripotent cells into polarized epiblast.
Shaohua Li, Yanmei Qi, K. McKee, Jie Liu, J. Hsu, P. Yurchenco   +5 more
semanticscholar   +1 more source

Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem Cells

Stem Cells, 2016
In human embryonic stem cells (ESCs) the transcription factor Zeb2 regulates neuroectoderm versus mesendoderm formation, but it is unclear how Zeb2 affects the global transcriptional regulatory network in these cell‐fate decisions.
Agata Stryjewska, Ruben Dries, T. Pieters, Griet Verstappen, A. Conidi, Kathleen Coddens, Annick Francis, L. Umans, W. V. van Ijcken, G. Berx, L. V. van Grunsven, F. Grosveld, S. Goossens, J. Haigh, D. Huylebroeck   +14 more
semanticscholar   +1 more source